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Reducing hair loss during chemotherapy: an interview with Richard Paxman

The basic principle of chemotherapy is to damage the mitotic and metabolic processes in the cancer cells. The chemotherapy doesn't just target the cancer cells, it also targets the healthy cells, specifically ones that are rapidly dividing - our hair follicles are also rapidly dividing. We see damage to those hair cells, which then causes the hair to fall out.

From Paxman 19 Apr 2016

Exposure to homicide during pregnancy linked to increased risk of prematurity, low birth weight

In a recent paper published in the Journal of Development Economics, researchers Professor Marco Manacorda (Queen Mary University of London) and Dr Martin Foureaux Koppensteiner (University of Leicester) focused on evidence from the exposure of day-to-day violence in Brazil by analysing the birth outcomes of children whose mothers were exposed to local violence, as measured by homicide rates in small Brazilian municipalities and the neighbourhoods of the city of Fortaleza.

18 Apr 2016

More than half of U.S. adults believe today's kids have diminished emotional and mental health

More than half of adults believe children today are more stressed, experience less quality family time and have worse mental and emotional health than children in past generations, according to the C.S. Mott Children's Hospital National Poll on Children's Health.

18 Apr 2016

Professor outlines effects of sports-specific counseling on injury outcomes in youth athletes

Neeru Jayanthi, MD, Associate Professor of Orthopedics and Sports Medicine at Emory University Sports Medicine Center in Atlanta, GA, presented "The Effects of Serial Sports Training Risk Assessment and Counseling in Kids (T.R.A.C.K.)" at the 25th Annual Meeting of the American Medical Society for Sports Medicine in Dallas, TX.

18 Apr 2016

False-positive mammogram results may have varied effects on subsequent screening behavior of women

Depending on when they received their last mammogram, women who receive a false-positive result are more or less likely to get screened at recommended intervals, according to preliminary findings from a University of North Carolina Comprehensive Cancer Center study.

18 Apr 2016

Scientists discover underlying mechanisms of nerve damage

Recent research by Sandra Rieger, Ph.D., of the MDI Biological Laboratory identifying the underlying mechanisms of peripheral neuropathy, or nerve damage, has raised the prospect that drug therapies can be developed for the treatment of this condition, which causes pain, numbness and/or tingling in the hands and feet. The research was published March 28 in the Proceedings of the National Academy of Sciences.

16 Apr 2016

Mouse model offers insight into molecular, neurological basis of stuttering

Mice that vocalize in a repetitive, halting pattern similar to human stuttering may provide insight into a condition that has perplexed scientists for centuries, according to a new study by researchers at Washington University School of Medicine in St. Louis and the National Institutes of Health.

16 Apr 2016

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

The removal of the enzyme Dnmt1 during oligodendrocyte progenitor cell (OPC) differentiation in the central nervous system resulted in inefficient myelin formation and neurological deterioration, including loss of control of bodily movements, in mice, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the medical journal Cell Reports. The results could lead to a new understanding of multiple sclerosis and other myelin disorders in humans.

16 Apr 2016

FOXO proteins affect dozens of genes common to worms, flies, mice and humans

Whether a creature is a worm, a fly, a mouse, or a human, death inevitably awaits. And not only do these organisms share a common fate, but also, according to a new study, they may share some of the specific mechanisms of mortality. The researchers found that in all four species, there are 46 genes regulated by the same family of "FOXO" proteins known to be central in aging and longevity.

16 Apr 2016

Physicians failing to talk to stroke patients about end-of-life treatment preferences

US research suggests that physician-patient discussion about limitations on life-sustaining interventions following ischaemic stroke is low, poorly documented and often left too late.

14 Apr 2016

Minimally important dyspnoea, fatigue changes in PAH patients defined

Researchers say that a change of around 1 unit in Borg dyspnoea or fatigue scores signifies an important change in patients with pulmonary arterial hypertension.

13 Apr 2016

Telemedicine makes diagnosis and treatment more easy, cost-effective for ASD patient families

Telemedicine - connecting health care providers and patients via computer or smart phone for diagnosis and treatment -- has been making it easier, and more cost-effective, to "see" the doctor. Using a camera-enabled computer or smart phone, patients with common health concerns can get some diagnoses without leaving their homes. Emergency room doctors and nurses are able to communicate with their peers in larger trauma centers via computer, as well.

13 Apr 2016

Spread of STIs, peer pressure may have transformed prehistoric humans to monogamists

Prehistoric humans may have developed social norms that favour monogamy and punish polygamy thanks to the presence of sexually transmitted infections (STIs) and peer pressure, according to new research from the University of Waterloo in Canada.

13 Apr 2016

PTSD patients carry long-term burden even with early clinical interventions

The majority of people with post-traumatic stress disorder (PTSD) recover after early treatment -- but a substantial number still suffer for years after a traumatic event even with early clinical interventions, according to a study publishing online April 12, 2016 in The Journal of Clinical Psychiatry.

13 Apr 2016

Study finds no difference in outcomes for children raised by same-sex parents

Children raised by same-sex female parents with a stable family life show no difference in general health, emotional difficulties, coping and learning behavior, compared to children of different-sex parents in similarly stable relationships, concludes a study in the April Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The journal is published by Wolters Kluwer.

13 Apr 2016

RedHill Biopharma initiates phase II study of BEKINDA for irritable bowel syndrome

RedHill Biopharma Ltd. (NASDAQ; RDHL) (TASE: RDHL) (“RedHill” or the “Company”), a biopharmaceutical company primarily focused on development and commercialization of late clinical-stage, proprietary, orally-administered, small molecule drugs for inflammatory and gastrointestinal diseases, including cancer, today announced that it has initiated a randomized, double-blind, 2-arm parallel group Phase II clinical study in the U.S. evaluating the safety and efficacy of BEKINDA™ 12 mg in patients with diarrhea-predominant irritable bowel syndrome (IBS-D).

13 Apr 2016

Overly controlling feeding practices may lead to emotional eating in later childhood

Parents who use very overly controlling feeding practices with their children, such as using food as a reward or a treat, could be unintentionally teaching their children to rely on food to deal with their emotions. These children may be more likely to 'emotionally eat' later in childhood.

12 Apr 2016

Mild traumatic brain injury can affect quality of parent-child relationships

A study published in the Journal of Neuropsychology, reveals the adverse effects of mild traumatic brain injury (mTBI) on the quality parent-child relationships. The young brain is particularly vulnerable to injury and one of the first visible signs of social difficulties in young children is a decline in their relationship with their parents. Parents should watch for emotional and behavioural changes in their children.

12 Apr 2016

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

In a new study, researchers from Columbia University Medical Center described a new mouse model featuring a combination of genetic and environmental risk factors that can trigger the compulsive restriction of food intake seen in patients with anorexia nervosa. The findings may help to identify new prevention and treatment strategies for the eating disorder in humans.

12 Apr 2016

Increased expression of VEGF-A promotes three common aging-related eye conditions

A Massachusetts General Hospital investigator has found that increased expression of the angiogenic factor VEGF-A promotes three common aging-related eye conditions - both versions of age-related macular degeneration (AMD) and also cataracts - in an animal model.

12 Apr 2016

Stress News and Research

Reducing hair loss during chemotherapy: an interview with Richard Paxman

Exposure to homicide during pregnancy linked to increased risk of prematurity, low birth weight

More than half of U.S. adults believe today's kids have diminished emotional and mental health

Professor outlines effects of sports-specific counseling on injury outcomes in youth athletes

False-positive mammogram results may have varied effects on subsequent screening behavior of women

Scientists discover underlying mechanisms of nerve damage

Mouse model offers insight into molecular, neurological basis of stuttering

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

FOXO proteins affect dozens of genes common to worms, flies, mice and humans

Physicians failing to talk to stroke patients about end-of-life treatment preferences

Minimally important dyspnoea, fatigue changes in PAH patients defined

Telemedicine makes diagnosis and treatment more easy, cost-effective for ASD patient families

Spread of STIs, peer pressure may have transformed prehistoric humans to monogamists

PTSD patients carry long-term burden even with early clinical interventions

Study finds no difference in outcomes for children raised by same-sex parents

RedHill Biopharma initiates phase II study of BEKINDA for irritable bowel syndrome

Overly controlling feeding practices may lead to emotional eating in later childhood

Mild traumatic brain injury can affect quality of parent-child relationships

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

Increased expression of VEGF-A promotes three common aging-related eye conditions

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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