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Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells.

26 Aug 2019

Researchers target cancer's protective barrier

Cancer cells are notorious for their camouflage work, which enables them to escape immune targeting. Now scientists are learning how to strip away the disguise and allow the immune system to do its work, by targeting cells called myeloid-derived suppressor cells (MDSCs) that shield the tumor. This would also enhance the effectiveness of newer cancer immunotherapies like Chimeric-Antigen Receptor T cell (CAR-T).

26 Aug 2019

Researchers discover pivotal role for bacterial sex in evolution of mammalian microbiome

In a pioneer study now published in Proceedings of the National Academy of Science - USA, the research team led by Isabel Gordo, from the Instituto Gulbenkian de Ciência, in collaboration with researcher Michael Lässig of Cologne University, used healthy mice to study real-time gut colonization and discovered a pivotal role for bacterial sex in the evolution of the mammalian microbiome.

25 Aug 2019

Scientists identify how nature builds with chitin

Writers know the power of the pen, but scientists are just discovering its secrets.

25 Aug 2019

Sophisticated chip mimics the effects of osteoarthritis to develop effective drugs

A sophisticated chip the size of a coin in which cartilage can be cultivated and which can later be subjected to mechanical stress such that it generates the effects of Osteoarthrosis.

25 Aug 2019

Caltech researchers determine how memories form and fade

Why is it that you can remember the name of your childhood best friend that you haven't seen in years yet easily forget the name of a person you just met a moment ago? In other words, why are some memories stable over decades, while others fade within minutes?

25 Aug 2019

Astrocytes help the brain to establish long-lasting memories

Star-shaped cells called astrocytes help the brain establish long-lasting memories, Salk researchers have discovered.

25 Aug 2019

New type of vaccine targets deadly tuberculosis

Australian medical researchers from the Centenary Institute and the University of Sydney have successfully developed and tested a new type of vaccine targeting tuberculosis (TB), the world's top infectious disease killer.

25 Aug 2019

Caregivers of people with dementia experience accumulation of sleep loss

Caregivers of people with dementia lose between 2.5 to 3.5 hours of sleep weekly due to difficulty falling asleep and staying asleep — a negative for themselves and potentially for those who receive their care, Baylor University researchers say.

23 Aug 2019

FDA finds inconsistent amounts of belladonna in certain homeopathic teething tablets

The U.S. Food and Drug Administration announced today that its laboratory analysis found inconsistent amounts of belladonna, a toxic substance, in certain homeopathic teething tablets, sometimes far exceeding the amount claimed on the label.

23 Aug 2019

Living Cells Can Record and Track Genomic Events with New “Designer Cell” Computer Technology

Published in Molecular Cell, researchers at Massachusetts Institute of Technology (MIT) have developed a new technology that uses DNA to process and store information in living cells.

23 Aug 2019

Head-to-head comparison of three breast cancer drugs reveals important differences

Every year, more than 250,000 women in the U.S. are diagnosed with breast cancer. When detected early, patients with the most common form--which tests positive for hormone receptors (HR+) and negative for the HER2 receptor--usually respond well to treatment.

23 Aug 2019

Study uncovers link between dietary zinc and protection against Streptococcus pneumoniae

Researchers have uncovered a crucial link between dietary zinc intake and protection against Streptococcus pneumoniae, the primary bacterial cause of pneumonia.

23 Aug 2019

Researchers create synthetic biologic system to deliver medicine, treat wounds for soldiers

For the first time, scientists built a synthetic biologic system with compartments like real cells. This Army project at the University of Massachusetts Amherst could lead to materials that provide new avenues to deliver medicine, treat wounds and purify water for Soldiers.

23 Aug 2019

Harnessing power of CRISPR to control behavior of DNA-responsive materials

The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide position of the vast reaches of the genome.

23 Aug 2019

Research team develops microbiome-based index for assessing skin health

Microbiomes aren't just for understanding and modulating gut health - skin, our largest organ, hosts a vibrant and complex microbiome that can provide health insights. An international research team has developed an index to better understand skin health across human populations.

22 Aug 2019

Vaping promotes the same cellular responses found in smokers with emphysema

E-cigarette "vaping" is widely assumed to be safer than cigarette smoking, but scientists at the University of North Carolina School of Medicine have uncovered evidence suggesting that vaping promotes the same cellular responses found in smokers who suffer with emphysema.

22 Aug 2019

Ludwig study uncovers novel vulnerability in MYC-driven cancers

A Ludwig Cancer Research study has uncovered a novel vulnerability in tumors that are driven by a common cancer gene known as MYC. Such cancers, it found, are highly dependent on the cell's machinery for making fats and other lipids.

22 Aug 2019

Lessons from animal brains can help artificial intelligence to overcome difficult barriers

Artificial intelligence (AI) still has a lot to learn from animal brains, says Cold Spring Harbor Laboratory neuroscientist Anthony Zador. Now, he's hoping that lessons from neuroscience can help the next generation of artificial intelligence overcome some particularly difficult barriers.

22 Aug 2019

Pittcon accepting applications for 2020 Pittsburgh Conference Memorial National College Grants

The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon) and its co-sponsoring technical societies, the Spectroscopy Society of Pittsburgh (SSP) and the Society for Analytical Chemists of Pittsburgh (SACP) are pleased to accept applications for the 2020 Pittsburgh Conference Memorial National College Grants (PCMNCG) awards program.

From Pittcon 22 Aug 2019

Laboratory News and Research

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

Researchers target cancer's protective barrier

Researchers discover pivotal role for bacterial sex in evolution of mammalian microbiome

Scientists identify how nature builds with chitin

Sophisticated chip mimics the effects of osteoarthritis to develop effective drugs

Caltech researchers determine how memories form and fade

Astrocytes help the brain to establish long-lasting memories

New type of vaccine targets deadly tuberculosis

Caregivers of people with dementia experience accumulation of sleep loss

FDA finds inconsistent amounts of belladonna in certain homeopathic teething tablets

Living Cells Can Record and Track Genomic Events with New “Designer Cell” Computer Technology

Head-to-head comparison of three breast cancer drugs reveals important differences

Study uncovers link between dietary zinc and protection against Streptococcus pneumoniae

Researchers create synthetic biologic system to deliver medicine, treat wounds for soldiers

Harnessing power of CRISPR to control behavior of DNA-responsive materials

Research team develops microbiome-based index for assessing skin health

Vaping promotes the same cellular responses found in smokers with emphysema

Ludwig study uncovers novel vulnerability in MYC-driven cancers

Lessons from animal brains can help artificial intelligence to overcome difficult barriers

Pittcon accepting applications for 2020 Pittsburgh Conference Memorial National College Grants

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