Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Compound derived from creosote bush slows aging in mice

Aspirin didn't pan out. Neither did two other potential anti-aging agents.

3 Jun 2007

Common cancer gene p53 sends death order to tiny killer

Scientists at Johns Hopkins have discovered one way the p53 gene does what it's known for stopping the colon cancer cells.

1 Jun 2007

Study challenges conventional wisdom about cancer cells

A team of St. Jude investigators challenged conventional wisdom about the eye cancer retinoblastoma by using a mouse model that allowed them to study the tumors as they develop and grow.

27 May 2007

Regular aspirin intake only reduces incidence of colorectal tumors that overexpress COX-2

Aspirin therapy's ability to reduce the risk of colorectal cancer, an association seen in a large number of studies, appears to depend on the drug's inhibition of the COX-2 enzyme, the action that also underlies aspirin's usefulness for treating pain and inflammation.

24 May 2007

Neuronal pathology of Fragile X syndrome studied

Fragile X syndrome is the most common form of inherited mental retardation, occurring in 1 in 3600 males and 1 in 4000 to 6000 females.

24 May 2007

Natural immune-control system may aid treatment of autoimmune disease and tissue rejection

The immune system's ability to police itself may offer a new method of arresting the cells responsible for autoimmune diseases such as multiple sclerosis and for the rejection of transplanted organs and tissues, scientists at Dana-Farber Cancer Institute report in a study in the May issue of the journal Immunity.

18 May 2007

Link between extreme sleep disorder and onset of parkinsonism or dementia

Mayo Clinic researchers and a group of international collaborators have discovered a correlation between an extreme form of sleep disorder and eventual onset of parkinsonism or dementia.

17 May 2007

Lack of association between Rh status, Rh immune globulin in pregnancy and autism

The increase in the number of diagnosed cases of autism in recent years has sparked concern that environmental toxins may cause this complex disorder.

17 May 2007

Herpes infection may be symbiotic

Mice with chronic herpes virus infections can better resist the bacterium that causes plague and a bacterium that causes one kind of food poisoning, researchers report in Nature.

17 May 2007

Health effects of polyphenols

Polyphenols, dietary substances from vegetables, fruits and green tea, bring about a change in the energy metabolism.

15 May 2007

Cardiotrophin 1 molecule shows potential for diagnosing hypertensive cardiopathy

Scientists from the Center for Applied Medical Research (CIMA) from the University of Navarra investigate whether cardiotrophin 1, a molecule that can be measured in blood, can be used as a diagnostic marker for hypertensive cardiopathy.

11 May 2007

Stent thrombosis

Over the last year, it's been rare to utter the word "stent" without at least thinking "thrombosis," an uncommon but serious complication that's been on the minds of interventional cardiologists and patients alike.

11 May 2007

CT and MRI are highly accurate at determining which patients would be optimal candidates for liver transplantation

CT and MRI are highly accurate at determining which patients would be optimal candidates for liver transplantation, says a recent study.

11 May 2007

Theophylline offers relief for unexplained chest pain

The discomfort caused by esophageal (non-cardiac) chest pain is often severe, driving many patients to emergency rooms and physicians' offices despite the fact that the ailment has no definable pathology.

10 May 2007

First comprehensive profile of cell movement

Researchers at the University of California, San Diego (UCSD) School of Medicine have developed new technology which, combined with proteomics, the large-scale study of the structure and function of proteins and their functions, has allowed them to map an extensive network of the signaling proteins that control cell movement.

8 May 2007

Molecule that destroys bone also protects it

An immune system component that is a primary cause of bone destruction and inflammation in autoimmune diseases such as rheumatoid arthritis actually protects bone in the oral cavity from infectious pathogens that play a major role in periodontal disease in humans, research at the University at Buffalo has shown.

7 May 2007

Nanoparticles found near plaque-filled arteries

Scientific evidence increasingly links arterial calcification to the presence of nanosized particles so small that some scientists question whether a nanoparticle can live and, if so, play a viable role in causing disease.

1 May 2007

Environment rich in sensory stimuli restores memory in mice with neurodegeneration

Mice whose brains had lost a large number of neurons due to neurodegeneration regained long-term memories and the ability to learn after their surroundings were enriched with toys and other sensory stimuli, according to new studies by Howard Hughes Medical Institute researchers.

30 Apr 2007

Link found between bile duct obstruction and bile duct cancer

When bile duct cancer cells were placed in the liver of animals with bile duct obstruction, they grew more rapidly than identical cells placed in animals without bile duct obstruction.

30 Apr 2007

A need to assess risks involved with spinal manipulation in children

Researchers are calling for the creation of a collaborative registry to assess the risk of serious injuries when treating children using spinal manipulation.

27 Apr 2007