Myocardial Infarction News and Research

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CYP2C19 gene variants undermine clopidogrel stroke prevention

The first look at CYP2C19 mutations in the context of a randomised controlled trial has confirmed suspicions that they affect the efficacy of clopidogrel in patients with acute stroke.

24 Jun 2016

Protein-based CHD risk score developed

Researchers have screened over 1000 plasma proteins to develop a predictive score in patients with stable coronary heart disease.

22 Jun 2016

Diabetes increases risk of dying from heart attack by 50%

Having diabetes increases the risk of dying from the effects of a heart attack by around 50 per cent, according to a widespread study.

22 Jun 2016

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

A new meta-analysis published in Clinical Nutrition found that cardiac surgery patients who received omega-3 polyunsaturated fatty acids (compared to placebo) in advance of surgery experienced reduced postoperative cardiac arrhythmias and significantly reduced the length of hospital stay by up to 2.4 days. The results are based on 11 RCT's with 1038 patients.

21 Jun 2016

Post-MI angina linked to increased late readmission risk

US researchers are calling for greater surveillance and treatment of post-myocardial infarction angina after their findings show an increased risk of late readmission among patients with angina symptoms at 30 days.

18 Jun 2016

New study may provide more insights into effects of physician-hospital integration

The Affordable Care Act and changing economic conditions have encouraged the integration of physicians and hospitals, particularly through accountable care organizations and medical homes.

17 Jun 2016

Sleep-disordered breathing increases cardiovascular risk in ACS patients

Sleep-disordered breathing is an important risk factor for major adverse cardiocerebrovascular events among patients with acute coronary syndromes, Japanese research shows.

17 Jun 2016

CHD rates decrease significantly in the U.S.

Significant improvements seen across multiple sociodemographic groups, according to a new study in the American Journal of Preventive Medicine

15 Jun 2016

Liraglutide cardioprotective in high-risk Type 2 diabetes patients

Findings of the LEADER trial show that liraglutide treatment may confer a reduced risk of cardiovascular events in patients with Type 2 diabetes and a high vascular risk.

15 Jun 2016

Mortality risk high among diabetes patients with prior CV events

Patients with Type 2 diabetes and acute coronary syndromes have a substantially increased risk of death in the 18 months after hospital admission for subsequent major nonfatal cardiovascular events, US researchers report.

15 Jun 2016

Age no barrier to vorapaxar use in ACS

The protease-activated receptor 1 inhibitor vorapaxar offers the same benefits to older and younger patients with non-ST segment elevation acute coronary syndromes, shows further analysis of the TRACER trial.

14 Jun 2016

Post PCI symmetry important for good clinical outcome

Postprocedural asymmetry following percutaneous coronary intervention is associated with an increased risk of adverse clinical outcome, particularly in patients with suboptimal expansion, researchers report.

9 Jun 2016

TAVI matches SAVR for early and midterm mortality

Transcatheter aortic valve implantation has similar early and midterm mortality to surgical aortic valve replacement in patients with aortic stenosis, including those at low to intermediate risk, show results of a systematic review and meta-analysis.

8 Jun 2016

Unsafe antiplatelet use persists in PCI patients

Contraindicated antiplatelet use is rare but persists in patients undergoing percutaneous coronary intervention, show US study data.

8 Jun 2016

New ‘hospital-level measure of value’ can inform consumers about quality, costs of health care choices

In the United States, the transition from volume to value dominates discussions of health care reform. While shared decision making might help patients determine whether to get care, transparency in procedure- and hospital-specific value measures would help them determine where to get care.

7 Jun 2016

Rapid NSTEMI exclusion becoming reality

Two studies show that modern high-sensitivity troponin I assays can help physicians to rapidly identify patients with a very low likelihood of having non-ST-segment elevation myocardial infarction.

4 Jun 2016

Multiple cell and gene therapies can enhance cardiac function in mice modeled with MI

Researchers at the University of Utah compared the therapeutic potential of umbilical cord-derived sub-epithelial cells (UC-SECs), bone marrow-derived mesenchymal stem cells (BM-MSCs) and induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) -- all derived from human tissue -- along with genes (S100a1 and SDF-1a) and growth factor (VEGF165) to evaluate how injected biologics might enhance cardiac function in mice modeled with myocardial infarction (MI; commonly referred to as heart attack).

2 Jun 2016

Myocardial Infarction News and Research

CYP2C19 gene variants undermine clopidogrel stroke prevention

Protein-based CHD risk score developed

Diabetes increases risk of dying from heart attack by 50%

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

Post-MI angina linked to increased late readmission risk

New study may provide more insights into effects of physician-hospital integration

Sleep-disordered breathing increases cardiovascular risk in ACS patients

CHD rates decrease significantly in the U.S.

Liraglutide cardioprotective in high-risk Type 2 diabetes patients

Mortality risk high among diabetes patients with prior CV events

Age no barrier to vorapaxar use in ACS

Post PCI symmetry important for good clinical outcome

TAVI matches SAVR for early and midterm mortality

Unsafe antiplatelet use persists in PCI patients

New ‘hospital-level measure of value’ can inform consumers about quality, costs of health care choices

Rapid NSTEMI exclusion becoming reality

Multiple cell and gene therapies can enhance cardiac function in mice modeled with MI

Just one stroke risk factor signals anticoagulation need in AF

Readmission rates after major cancer procedures depend on patient cohort, hospital characteristics

Migraine increases vascular disease risk in women

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