Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Genetic differences may explain why many Asian women who never smoked develop lung cancer

Analysis of three genetic mechanisms that cause non-small cell lung cancer might explain why East Asians respond better than other ethnic groups to a certain type of chemotherapy, a team led by UT Southwestern Medical Center researchers has found.

27 Apr 2007

Influence of the cellular microenvironment on breast cancer

This month The American Journal of Pathology highlights the influence of the cellular microenvironment on breast cancer by promoting three articles from the current issue.

27 Apr 2007

Researchers develop cantilever biosensor with potential for medical diagnostic testing

A Drexel University engineering professor has developed a millimeter-size cantilever biosensor that can detect cells and proteins in trace samples and in only minutes.

26 Apr 2007

Naproxen and celecoxib do not prevent Alzheimer's disease

Over-the-counter pain medication naproxen and prescription pain reliever celecoxib do not prevent Alzheimer's disease, according to a study published April 25, 2007, in the online edition of Neurology, the scientific journal of the American Academy of Neurology.

26 Apr 2007

Surprising new theory on antibiotic resistance

A surprising new theory developed at the University of Nebraska Medical Center (UNMC) in Omaha, Nebraska, suggests that some bacterial cells act as "suicide bombers" in cell communities, with the altruistic intention of dying for the common good - and in the process, strengthening other cells that then become resistant to antibiotic drugs.

25 Apr 2007

Humanizing approaches to dementia care may extend patients' lives

Through an intensive comparative study of two nursing home units using contrasting approaches to dementia care for elders with severely disturbed behaviors, Central Michigan University professor of anthropology Athena McLean has found that "humanizing" approaches to dementia care may not only extend quality of life for patients, but also their length of life.

25 Apr 2007

Gene analysis explains ethnic differences in sensitivity to chemotherapy in lung cancer

25 Apr 2007

Female alcoholics may sustain greater cognitive damage than male alcoholics

Researchers and clinicians already know that alcohol abuse and/or dependence can lead to severe and potentially irreversible brain damage.

24 Apr 2007

Naturally occurring compound found in many fruits and vegetables as well as red wine, selectively kills leukemia cells

These findings, which were published online March 20 in the Journal of Biological Chemistry and will be in press on May 4, offer hope for a more selective, less toxic therapy for leukemia.

24 Apr 2007

Klotho proteins important players in future therapies for diabetes, obesity and kidney disease

A relative of the anti-aging gene Klotho helps activate a hormone that can lower blood glucose levels in fat cells of mice, making it a novel target for developing drugs to treat human obesity and diabetes, UT Southwestern Medical Center researchers have found.

24 Apr 2007

Why bladder cancer hits more men than women

Scientists have discovered one of the reasons why bladder cancer is so much more prevalent in men than women: A molecular receptor or protein that is much more active in men than women plays a role in the development of the disease.

21 Apr 2007

Long-term survival probability in men with clinically localized prostate cancer

Randomized studies comparing conservative therapy to definitive therapy in men with prostate cancer (CaP) are underway, but not yet available.

20 Apr 2007

Jefferson participates in global study to extend effectiveness of drug for Parkinson's

After Parkinson's disease patients use the drug levodopa or L-dopa for several years as a treatment for restoring the cellular communication that controls muscle movement by replacing lost dopamine, they begin to experience motor complications that include a shortened response to each dose of L-dopa.

19 Apr 2007

New understanding of genetics behind Noonan Syndrome

Researchers have discovered that the genetic malfunction that causes a form of mental retardation called Noonan Syndrome (NS) produces an imbalance in the genesis of two types of cells in the developing embryonic brain.

19 Apr 2007

Researchers observer proteins important in Alzheimer's, Parkinson's moving along axons

Using a novel video-imaging system, researchers at the University of Pennsylvania School of Medicine have been able to observe proteins important in Alzheimer's and Parkinson's disease moving along axons, extensions of nerve cells that carry proteins away from the cell body.

18 Apr 2007