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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

WPI receives patent for novel method of reprogramming human skin cells

Cell therapies for a range of serious conditions, including heart attacks, diabetes, and traumatic injuries, will be accelerated by research at Worcester Polytechnic Institute that yielded a newly patented method of converting human skin cells into engines of wound healing and tissue regeneration.

25 May 2016

Study provides better understanding of sequence of genetic events in colorectal cancer premalignancy

Whole-exome sequencing of both colorectal adenomas (precancers often called polyps) and intestinal mucosa at risk for developing into adenomas from patients with familial adenomatous polyposis (FAP) has generated a comprehensive picture of the genomic alterations that characterize the evolution of normal mucosa to precancer.

25 May 2016

Early epigenetic changes could open way for new preventative strategies for ovarian cancer

Research revealing early changes at epigenetic level points to possible new prevention strategies for ovarian cancer. The discovery of early changes in the cells of the Fallopian tubes of women carrying the BRCA genetic mutation could open the way for new preventative strategies for ovarian cancer, reducing the need for invasive surgery, according to research published today in science journal Nature Communications.

24 May 2016

Researchers find genetic mutations linked to increased risk factor for PTSD

In the largest study of DNA samples from service members with Post-Traumatic Stress Disorder (PTSD), researchers have identified genetic mutations that may be associated with an increased risk factor for PTSD.

24 May 2016

Rare mutation may reduce risk of developing arteriosclerosis by 34%

According to new international research, just less than one per cent of the population is naturally protected against developing chronic coronary artery diseases.

24 May 2016

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

An endoscopist's knowledge of a positive Cologuard test improves colonoscopy performance, according to a poster presentation at last week's Digestive Disease Week conference.

24 May 2016

Researchers identify mutations that may stimulate early cancer growth in precancerous colorectal tissue

Researchers at The University of Texas MD Anderson Cancer Center have discovered mutations that may fuel early cancer growth in precancerous colorectal tissue from high-risk patients.

24 May 2016

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Scientists of the German Center for Diabetes Research led by the German Institute of Human Nutrition have shown in a mouse model that the epigenetic modification of the Igfbp2 gene observed in the young animal precedes a fatty liver in the adult animal later in life.

24 May 2016

Changes in intestinal microbiota linked to primary sclerosing cholangitis

Primary sclerosing cholangitis, also known as PSC, is a liver disease with no effective medical treatment. Liver transplantation is the only proven long-term treatment of PSC, although only a fraction of individuals with PSC will ultimately require it.

23 May 2016

Chromatrap announces new 96-well high throughput purification plate for production of ultra-pure DNA

Chromatrap has announced a new 96-well high throughput purification plate for production of ultra-pure DNA.

From Chromatrap® - Porvair Sciences Ltd 23 May 2016

Could a new test improve bowel cancer screening uptake? An interview with Professor Halloran

The most recent complete data for England (2014/15) shows an average uptake of the guaiac Faecal Occult Blood Tests (gFOBT) from those invited by the NHS Bowel Cancer Screening Programme (BCSP) of 58.22%.

23 May 2016

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Colorectal cancer is the second most common cause of cancer-related deaths in the Western world, mainly because it is usually diagnosed too late. Finding ways to identify those people who are at increased risk of developing colon cancer is therefore crucial, a researcher will tell the annual conference of the European Society of Human Genetics today.

23 May 2016

CSU researchers develop colorful potatoes that are high in antioxidants, rich in nutrients

Purple potatoes might not be the first thing that comes to mind when trying to increase vitamin, mineral and antioxidant intake. However, a group of researchers from Colorado State University have recently developed potato varieties that satisfy these nutritional needs and could act as a preventive measure to several diseases.

23 May 2016

LIGR-Seq tool opens door to developing new understanding of ncRNA function

What used to be dismissed by many as "junk DNA" is back with a vengeance as growing data points to the importance of non-coding RNAs (ncRNAs) -- genome's messages that do not code for proteins -- in development and disease.

21 May 2016

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

AstraZeneca and its global biologics research and development arm, MedImmune, will provide an update on their extensive oncology pipeline at the annual meeting of the American Society of Clinical Oncology in Chicago, USA, on 3-7 June 2016.

20 May 2016

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Chronix Biomedical, Inc., a developer of blood-based molecular diagnostics, today announces positive data from a blinded proof of concept clinical study, assessing the utility of tumor cell-free DNA as a predictor of therapeutic response to immunotherapy after the first cycle of treatment in eight different types of cancer.

20 May 2016

DNA News and Research

Further Reading

WPI receives patent for novel method of reprogramming human skin cells

Study provides better understanding of sequence of genetic events in colorectal cancer premalignancy

Early epigenetic changes could open way for new preventative strategies for ovarian cancer

Researchers find genetic mutations linked to increased risk factor for PTSD

Rare mutation may reduce risk of developing arteriosclerosis by 34%

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

Researchers identify mutations that may stimulate early cancer growth in precancerous colorectal tissue

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Changes in intestinal microbiota linked to primary sclerosing cholangitis

Chromatrap announces new 96-well high throughput purification plate for production of ultra-pure DNA

Could a new test improve bowel cancer screening uptake? An interview with Professor Halloran

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

CSU researchers develop colorful potatoes that are high in antioxidants, rich in nutrients

LIGR-Seq tool opens door to developing new understanding of ncRNA function

AstraZeneca, MedImmune to provide update on extensive oncology pipeline at ASCO 2016

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Brandeis scientists find new way for genetically identifying cell types in mouse brain

Radiation-immunotherapy combination can help treat melanoma

Microglia plays vital role in reducing effects of cocaine in the brain

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

eBook: A guide to RNA sequencing eBook

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