Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Effects of prion disease could be reversed if caught early enough

The researchers said that their findings support developing early treatments that aim to reduce levels of prion protein in the brains of people with prion disease.

31 Jan 2007

Scientists test technique for identifying newly recognized DNA variations that may influence disease risk

Rather than focus on errors and alterations in DNA sequence, the new technique highlights variations in the number of copies of a particular gene.

30 Jan 2007

An active mind delays the onset of Alzheimer's

Learning appears to slow the development of two brain lesions that are the hallmarks of Alzheimer's disease, scientists at UC Irvine have discovered. The finding suggests that the elderly, by keeping their minds active, can help delay the onset of this degenerative disease.

23 Jan 2007

Link between eating disorders and certain personality traits

Among the young women diagnosed as having anorexia or bulimia, 48.5% also suffer from a personality disorder.

23 Jan 2007

Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes

Researchers open the way for improved study of hepatitis C virus by devising a novel virus culture system that allows replication of patient-isolated virus in nontransformed hepatocytes, instead of culture-adapted virus strains in transformed cell lines.

23 Jan 2007

New screening process helps better diagnose oral cancers

Patients with early stage oral cancer may benefit from a more advanced screening process allowing for a more accurate diagnosis, according to a study presented at the plenary session at the Multidisciplinary Head and Neck Cancer Symposium in Rancho Mirage, Calif., co-sponsored by the American Society for Therapeutic Radiology and Oncology, the American Society of Clinical Oncology and the American Head and Neck Society.

18 Jan 2007

Simple diagnostic test detects genetic signs of lung cancer in sputum

DNA coughed up along with phlegm could point to lung cancer, say researchers at the University of Maryland School of Medicine who are developing an inexpensive and non-invasive gene probe to help diagnose early stage lung cancer in current and former smokers.

18 Jan 2007

Study shows why the body's immune system doesn't attack tissues in the small intestine

Answering one of the oldest questions in human physiology, researchers at Dana-Farber Cancer Institute have discovered why the body's immune system - perpetually on guard against foreign microbes like bacteria - doesn't attack tissues in the small intestine that harbor millions of bacteria cells.

9 Jan 2007

Cancer Research Technology and University of Manchester announce collaboration in oncology with AstraZeneca

Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, and The University of Manchester have entered into an agreement with AstraZeneca to establish a clinical pharmacology biomarker research and discovery collaboration.

20 Nov 2006

Doctors say antibiotics pointless for acute bronchitis

Researchers say they have found no evidence in current literature that antibiotics are effective in treating the vast majority of patients with acute bronchitis and say doctors should stop routinely prescribing them.

16 Nov 2006

Muscle protein myosin VI involved in the development of prostate cancer

Researchers at the Johns Hopkins Kimmel Cancer Center have for the first time implicated the muscle protein myosin VI in the development of prostate cancer and its spread.

8 Nov 2006

Targeted tumor therapy has paramount consequences for future expansion of nuclear medicine

Targeted tumor therapy lobs toxic payloads directly into tumors to destroy cancer cells while leaving normal cells unharmed.

20 Oct 2006

An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling

Using a combination of enzyme activity and metabolite profiling, we determined that this protein-whose function was previously unknown-serves as a key regulator of a lipid signaling network that contributes to cancer," said Benjamin F. Cravatt, a Scripps Research professor and a member of its Skaggs Institute for Chemical Biology who led the study.

20 Oct 2006

Vitamin D may slow down breast cancer

The authors of a new study are suggesting that vitamin D may slow down the progression of breast cancer.

17 Oct 2006

Discovery of mechanism by which Ebola and Marburg viruses cause disease

Researchers in the Greene Infectious Disease Laboratory at Columbia University's Mailman School of Public Health, the Centers for Disease Control and Prevention, and the Caribbean Primate Research Center have discovered a key mechanism by which the Filoviruses, Ebola and Marburg, cause disease.

16 Oct 2006

Researchers identifiy how immune system contributes to nerve fiber damage caused by multiple sclerosis

Researchers have identified how the body's own immune system contributes to the nerve fiber damage caused by multiple sclerosis, a finding that can potentially aid earlier diagnosis and improved treatment for this chronic disease.

16 Oct 2006

New clues about virulence of 1918 influenza virus

The first comprehensive analysis of an animal's immune response to the 1918 influenza virus provides new insights into the killer flu, report federally supported scientists in an article appearing online in the journal Nature.

28 Sep 2006

Multispectral imaging of clinically relevant cellular targets in tonsil and lymphoid tissue using semiconductor quantum dots

When pathologists examine tissue samples in order to diagnose cancer of the lymphatic system, they examine the relative amounts of a group of proteins known as Cluster of Differentiation markers.

25 Sep 2006

Insulin receptor stops progression of Alzheimer's disease

Stimulation of a receptor in the brain that controls insulin responses has been shown to halt or diminish the neurodegeneration of Alzheimer's disease, providing evidence that the disease can be treated in its early stages, according to a study by researchers at Rhode Island Hospital and Brown Medical School.

21 Sep 2006

Drugs that enhance the activity of calcineurin or NFAT could become a new treatment for type-2

Certain immune-suppressing drugs, such as those taken by patients who have had organ transplants, greatly increase the risk of developing diabetes. These drugs are known to put a stranglehold on a protein called calcineurin.

21 Sep 2006

Pathology News and Research

Further Reading

Effects of prion disease could be reversed if caught early enough

Scientists test technique for identifying newly recognized DNA variations that may influence disease risk

An active mind delays the onset of Alzheimer's

Link between eating disorders and certain personality traits

Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes

New screening process helps better diagnose oral cancers

Simple diagnostic test detects genetic signs of lung cancer in sputum

Study shows why the body's immune system doesn't attack tissues in the small intestine

Cancer Research Technology and University of Manchester announce collaboration in oncology with AstraZeneca

Doctors say antibiotics pointless for acute bronchitis

Muscle protein myosin VI involved in the development of prostate cancer

Targeted tumor therapy has paramount consequences for future expansion of nuclear medicine

An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling

Vitamin D may slow down breast cancer

Discovery of mechanism by which Ebola and Marburg viruses cause disease

Researchers identifiy how immune system contributes to nerve fiber damage caused by multiple sclerosis

New clues about virulence of 1918 influenza virus

Multispectral imaging of clinically relevant cellular targets in tonsil and lymphoid tissue using semiconductor quantum dots

Insulin receptor stops progression of Alzheimer's disease

Drugs that enhance the activity of calcineurin or NFAT could become a new treatment for type-2

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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