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NIH scientists discover an autoinflammatory disease caused by mutations in the LYN gene

Scientists have identified an autoinflammatory disease caused by mutations in the LYN gene, an important regulator of immune responses in health and disease.

28 Mar 2023

IU Cancer Center secures new, renewed ACS funding to support research and education programs

As part of a longstanding partnership, the Indiana University Melvin and Bren Simon Comprehensive Cancer Center has received new and renewed funding from the American Cancer Society to support research and education programs.

27 Mar 2023

Myeloid cells can harbor HIV in people taking antiretroviral therapy

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

27 Mar 2023

Computational approach used to understand the mechanisms of protein folding in tauopathies

A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases.

27 Mar 2023

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

The breast tumors of Asian, Black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center.

27 Mar 2023

Targeting the STING pathway with a combination strategy promotes antitumor activity

Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy.

27 Mar 2023

Discontinuing use of THC may reverse its effects on male fertility

A 2022 study from Oregon Health & Science University researchers confirmed that chronic use of cannabis may greatly impact male fertility and reproductive outcomes in nonhuman primates - but it was unclear whether the effects are permanent.

27 Mar 2023

Smart bandage may make treatment of chronic wounds easier, more effective

Most of the time, when someone gets a cut, scrape, burn, or other wound, the body takes care of itself and heals on its own.

24 Mar 2023

Hidden "super spreader" spaces associated with a predominance of asymptomatic cases of dengue

For mosquito-borne diseases such as dengue fever, the abundance of the insects in places where people gather has long served as the main barometer for infection risk.

23 Mar 2023

£1.3 million awarded to develop a new "point of care testing" kit for detecting Alzheimer's biomarkers

Scientists from Swansea University 's Institute for Innovative Materials, Processing and Numerical Technologies (IMPACT) and Japan have been awarded £1.3 million to develop a new "point of care testing" kit that can detect biomarkers for Alzheimer's Disease.

23 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

Higher plasma caffeine concentrations might reduce body fat and type 2 diabetes risk

In a recent study published in the journal BMJ Medicine, researchers in the United Kingdom and Sweden investigated the probable causality of long-term serum caffeine concentrations on type 2 diabetes (T2D), adiposity, and major cardiovascular diseases (CVDs).

22 Mar 2023

Study finds shared genetic risk variants across different substance use disorders

By combing through genomic data of over 1 million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used.

22 Mar 2023

Researchers identify the cellular glitches underlying a rare genetic disorder

The cellular glitches underlying a rare genetic disorder called activated PI3K Delta syndrome 2 (APDS2) have been identified by researchers at the Garvan Institute of Medical Research. The disorder is caused by genetic variations that disrupt immune cell signaling through a protein called PI3K.

21 Mar 2023

Diet and exercise programs alone won't curb the tide of childhood obesity

Focusing on immediate fixes such as diet and exercise programs alone won't curb the tide of childhood obesity, according to a new study that for the first time maps the complex pathways that lead to obesity in childhood.

21 Mar 2023

Girls born to obese mothers have a high risk of developing obesity

Women with obesity may share risk for the disease with their daughters, but not their sons, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

21 Mar 2023

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

The magnitude and quality of a key immune cell's response to vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine were considerably lower in people with prior SARS-CoV-2 infection compared to people without prior infection, a study has found.

20 Mar 2023

Indiana CTSI secures $38 million NIH funding to advance health research

The Indiana Clinical and Translational Sciences Institute (CTSI) has secured nearly $38 million in renewed funding from the National Institutes of Health for the next seven years -; the fourth consecutive successful grant submission for the statewide research enterprise.

20 Mar 2023

Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

20 Mar 2023

New technique lights up cancerous tumors during surgery

A new technique that combines highly detailed, real-time images of inside the body with a type of infrared light has, for the first time, been used during surgery to differentiate between cancerous tumors and healthy tissue.

20 Mar 2023

Medical Research News and Research

NIH scientists discover an autoinflammatory disease caused by mutations in the LYN gene

IU Cancer Center secures new, renewed ACS funding to support research and education programs

Myeloid cells can harbor HIV in people taking antiretroviral therapy

Computational approach used to understand the mechanisms of protein folding in tauopathies

Breast tumors of women from different racial groups have diverse cellular, microbial and genomic features

Targeting the STING pathway with a combination strategy promotes antitumor activity

Discontinuing use of THC may reverse its effects on male fertility

Smart bandage may make treatment of chronic wounds easier, more effective

Hidden "super spreader" spaces associated with a predominance of asymptomatic cases of dengue

£1.3 million awarded to develop a new "point of care testing" kit for detecting Alzheimer's biomarkers

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Higher plasma caffeine concentrations might reduce body fat and type 2 diabetes risk

Study finds shared genetic risk variants across different substance use disorders

Researchers identify the cellular glitches underlying a rare genetic disorder

Diet and exercise programs alone won't curb the tide of childhood obesity

Girls born to obese mothers have a high risk of developing obesity

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

Indiana CTSI secures $38 million NIH funding to advance health research

Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

New technique lights up cancerous tumors during surgery

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