Immune Response News and Research

RSS

Latest developments in prostate cancer research

New research on genes linked to hereditary prostate cancer helps scientists better understand how prostate cancer grows. Tests to find abnormal prostate cancer genes could also help tell which men are at high risk. They could then be tested more often. Further research could provide answers about the chemical changes that lead to prostate cancer. Then, perhaps, we could design drugs to reverse those changes.

12 Apr 2004

Protein kinase complex influences the outer layer of skin to control the eventual shape of the full-grown skeleton and skull

Continuing studies about an important regulatory protein kinase complex called I-kappa-B kinase (or IKK) have now shown that a subunit of IKK – IKK alpha – influences the outer layer of skin in developing mice to control the eventual shape of the full-grown skeleton and skull.

7 Apr 2004

New method to induce embryonic stem cells to develop into bone marrow and blood cells

Researchers at Northwestern University have devised a method to induce embryonic stem cells to develop into bone marrow and blood cells. Injecting the stem cells into the bone marrow cavity of mice whose bone marrow cells had been depleted restored production of blood cells, including cells of the immune system, which normally are created in the bone marrow.

6 Apr 2004

Scientists studying vaccinia virus, a relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation

Scientists at the University of Illinois at Urbana-Champaign studying vaccinia virus, a close relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation, a crucial anti-viral immune response of host cells.

6 Apr 2004

Gene of immune system linked to severe adverse drug reaction called Stevens-Johnson syndrome (SJS)

In a study of Han Chinese patients, researchers have for the first time directly linked a gene of the immune system to a severe adverse drug reaction called Stevens-Johnson syndrome (SJS), according to a Duke University Medical Center medical geneticist and collaborators in Taiwan.

1 Apr 2004

SARS virus vaccine stimulates protective immune response

An experimental vaccine prevents the SARS virus from replicating in laboratory mice, according to a new report in the April 1 issue of Nature. Scientists at the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health, developed the vaccine. The vaccine was tested in a mouse model of SARS infection recently validated by other NIAID investigators.

31 Mar 2004

Novel vaccine technology to suppress the growth of certain tumors

MedImmune, Inc. and Cerus Corporation have announced preclinical results demonstrating the effectiveness of a novel therapeutic vaccine technology in suppressing the growth of certain tumors.

From Baxter International Inc. 29 Mar 2004

Immunomodulator induces long-term anti-tumor activity

EntreMed, Inc., a clinical-stage biopharmaceutical company developing therapeutic candidates primarily for the treatment of cancer, today reported that three months following administration with ENMD 0996, preclinical animal models showed inhibition of metastases. Data presented demonstrated that ENMD 0996 specifically blocks the activity of basic fibroblast growth factor (FGF-2), a naturally-occurring protein that stimulates angiogenesis, but had no effect on other angiogenesis stimulators.

29 Mar 2004

Renowned researchers, scientists share advances in prevention, diagnosis, therapy

Leading researchers are gathering today for the 95th Annual Meeting of the American Association for Cancer Research (AACR), the premier multidisciplinary assembly, which features the latest developments in basic, prevention, translational and clinical cancer research. The meeting occurs from March 27 – 31, 2004 at the Orlando Convention Center, Fla.

27 Mar 2004

£5m for HIV/AIDS trial involving HIV patients in London, Moscow, South Africa and Australia

A joint Oxford University/Imperial College research programme into HIV/AIDS has received £5 million support from the Wellcome Trust to carry out a drug trial involving HIV patients in London, Moscow, South Africa and Australia.

24 Mar 2004

First US Tests of Bird-Flu Vaccine in Humans

Doctors are beginning the first test in the United States of a vaccine designed to protect people against one form of bird flu should an outbreak of the virus occur in humans. While the vaccine under study is not designed to protect against the precise bird-flu virus causing the current outbreak in poultry and in people, scientists will learn whether it protects against another strain of the virus that infects birds and people.

24 Mar 2004

New research may help prevent anthrax, bubonic plague and typhoid fever

The mechanism used by the bacteria that cause anthrax, bubonic plague and typhoid fever to avoid detection and destruction by the body’s normal immune response, leading to life-threatening bacterial infections, has been identified by researchers at the University of California, San Diego (UCSD) School of Medicine.

22 Mar 2004

Cigarette Smoking May Lower Rates of Neurodegenerative Diseases like Parkinson's and Alzheimer's

While the health risks of tobacco are well known, several studies have shown that people with a history of cigarette smoking have lower rates of neurodegenerative diseases like Parkinson's and Alzheimer's disease. However, the explanations for nicotine's neuroprotective effects continue to be debated.