Immune Response News and Research

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First FDA-approved cellular therapy for metastatic melanoma available in South Florida

Patients in South Florida with metastatic melanoma will soon have access to the first cellular therapy for this advanced form of skin cancer, following its recent approval by the Food and Drug Administration (FDA).

2 May 2024

New biomarker predicts immunotherapy response in gastrointestinal cancers

Despite significant progress in treating gastrointestinal (GI) cancers through surgical resection, chemotherapy, radiotherapy, and targeted therapy, the objective response rate (ORR) for immune checkpoint inhibitor (ICI) therapy remains low.

30 Apr 2024

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

Updated vaccine provides strong immune response against previous and emerging SARS-CoV-2 variants

New research using live SARS-CoV-2 virus reveals an updated vaccine provides a strong immune response against previous strains and emerging variants.

29 Apr 2024

Measles and rubella vaccine delivered via microarray patch shows promising results

The phase 1/2 randomized trial compared results from the measles and rubella vaccine delivered by a microarray patch, a small sticking plaster-like device with an array of microscopic projections that painlessly penetrate the skin and deliver the vaccine, or by conventional injection with a needle and syringe.

29 Apr 2024

Study rethinks immune system strategies to boost vaccine effectiveness

A recent Cell journal review explores key immunological assumptions to enhance our understanding of vaccine design, autoimmune responses, and immune system pathology, aiming to refine intervention strategies and theoretical frameworks in immunology.

28 Apr 2024

Aspirin's immune-boosting effects in colorectal cancer revealed

Study reveals that aspirin helps the body’s immune system detect and target cancer cells.

27 Apr 2024

Harnessing immune enhancement to combat drug-resistant tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.

26 Apr 2024

New study offers promising targets for universal influenza B vaccine

In a milestone study led by the Peter Doherty Institute of Infection and Immunity (Doherty Institute), researchers have identified fragments from influenza B viruses that the immune system consistently recognize, offering promising targets for a universal influenza B vaccine

26 Apr 2024

Study reveals surprising role of maternal cytokines in offspring psychiatric risk

Researchers at Weill Cornell Medicine have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for psychiatric conditions.

25 Apr 2024

Genetically modified mice reveal key players in immune defense against viruses

Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors.

25 Apr 2024

Bivalent COVID-19 vaccine boosts immunity but needs to be updated

A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to a Brazilian study reported in the Journal of Medical Virology.

25 Apr 2024

Prostaglandin E2: The culprit behind tumor immune evasion

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens.

24 Apr 2024

Giant virus takes down deadly brain parasite

The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an international collaboration, have discovered viruses that infect this harmful microbe.

24 Apr 2024

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Driven by the overuse of antimicrobials, pathogens are quickly building up resistances to once-successful treatments.

24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

The U.S. Food and Drug Administration (FDA) has approved the immunotherapy-boosting drug N-803, which is marketed under the brand name Anktiva, to be used in combination with the immunotherapy Bacillus Calmette-Guerin (BCG) for the treatment of patients with BCG-unresponsive non–muscle-invasive bladder cancer.

23 Apr 2024

Study discovers hidden mechanism behind rapid COVID variants

The SARS-CoV-2 virus that causes COVID has the unsettling ability of often generating variants of itself. Other viruses also mutate, but as SARS-CoV-2 quickly spread throughout the entire human population during the pandemic, killing millions, the virus' dynamic evolution posed a serious problem: it repeatedly challenged our bodies' immune response fighting the virus and hindered the process of getting updated vaccines ready.

23 Apr 2024

Study uncovers aspirin's role in colorectal cancer development and progression

Long-term daily use of aspirin can help to prevent the development and progression of colorectal cancer, but the mechanisms involved have been unclear.

22 Apr 2024

Engineered peptides show promise in cancer immunotherapy

In a new study published today in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cancer Center have designed a new method for developing immunotherapy drugs using engineered peptides to elicit a natural immune response inside the body.

22 Apr 2024

Immune Response News and Research

First FDA-approved cellular therapy for metastatic melanoma available in South Florida

New biomarker predicts immunotherapy response in gastrointestinal cancers

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Updated vaccine provides strong immune response against previous and emerging SARS-CoV-2 variants

Measles and rubella vaccine delivered via microarray patch shows promising results

Study rethinks immune system strategies to boost vaccine effectiveness

Aspirin's immune-boosting effects in colorectal cancer revealed

Harnessing immune enhancement to combat drug-resistant tuberculosis

New study offers promising targets for universal influenza B vaccine

Study reveals surprising role of maternal cytokines in offspring psychiatric risk

Genetically modified mice reveal key players in immune defense against viruses

Bivalent COVID-19 vaccine boosts immunity but needs to be updated

Prostaglandin E2: The culprit behind tumor immune evasion

Giant virus takes down deadly brain parasite

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

Study discovers hidden mechanism behind rapid COVID variants

Study uncovers aspirin's role in colorectal cancer development and progression

Engineered peptides show promise in cancer immunotherapy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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