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Study demonstrates potential of new approach for sorting out BRCA1 gene variants

Patients seeking certainty in genetic tests often receive a perplexing result. Many learn they carry a 'variant of unknown significance' of a disease-linked gene. Such variants might -- or equally might not -- increase disease risk.

19 Jun 2015

Florida Institute finalizes funding agreement with TransGenex Nanobiotech

The Florida Institute for the Commercialization of Public Research announced today that it has finalized a funding agreement with TransGenex Nanobiotech, Inc., a company that is developing nano-scale technologies for novel, cost-effective diagnostic and therapeutic agents against cancers and other inflammatory diseases.

19 Jun 2015

Scientists reveal new combination method that efficiently destroys cancer cells

Scientists at the Institut Pasteur and Inserm have successfully increased the infiltration of immune cells into tumors, thus inducing the immune system to block tumor growth. In an article published in Nature Immunology, the scientists show that, in combination with existing immunotherapies, this process efficiently destroys cancer cells.

18 Jun 2015

Value of Colorectal Cancer therapeutics market expected to increase $9.4 billion by 2020

Analysis from business intelligence provider GBI Research - Colorectal Cancer Therapeutics in Major Developed Markets to 2020 - states that the Colorectal Cancer (CRC) treatment market value will increase at a moderate Compound Annual Growth Rate (CAGR) of 1.8%, from $8.3 billion in 2013 to $9.4 billion by 2020.

18 Jun 2015

NIBIB-funded researcher develops new technique for tissue analysis

An NIBIB-funded researcher has developed a new technique that creates digital pictures of a tissue's chemical composition using light and a computer. The technique replaces the need for dyes or stains, which can be costly and require significant time and effort to apply.

18 Jun 2015

Researchers highlight important factors that impact early-stage breast cancer patients' access to BCT

The first comprehensive national review of breast-conserving therapy (BCT) shows that over the last 13 years rates of this treatment modality for early-stage breast cancer have increased at a steady pace. However, the review also highlights important demographic factors that impact which patients have access to BCT.

18 Jun 2015

Johns Hopkins researchers develop new imaging technology to help remove brain tumors safely

Brain surgery is famously difficult for good reason: When removing a tumor, for example, neurosurgeons walk a tightrope as they try to take out as much of the cancer as possible while keeping crucial brain tissue intact — and visually distinguishing the two is often impossible.

18 Jun 2015

Melanoma patients with high levels of H2A.Z.2 protein less likely to survive

Melanoma patients with high levels of a protein that controls the expression of pro-growth genes are less likely to survive, according to a study led by researchers at Icahn School of Medicine at Mount Sinai and published online in the journal Molecular Cell.

18 Jun 2015

Canadian and Israeli researchers meet to discuss underlying mechanisms that drive pancreatic cancer

Leading Canadian and Israeli scientists gathered at the Hebrew University of Jerusalem's Faculty of Medicine to attend a forum on pancreatic cancer research and help dedicate the Alex U. Soyka Pancreatic Cancer Research Project.

18 Jun 2015

Loyola tests new combination treatment for people living with cancer that has spread to spine

Loyola University Medical Center is the first center in the country to enroll patients in a clinical trial of a minimally invasive treatment for patients living with cancer that has spread to the spine.

17 Jun 2015

RPCI receives NCI grant to continue research program on photodynamic therapy for head and neck cancers

Roswell Park Cancer Institute has received continuation of a prestigious program project grant from the National Cancer Institute for research through the Roswell Park Photodynamic Therapy Center.

17 Jun 2015

La Jolla Institute researchers identify molecular pathway that maintains Treg cells' function

Regulatory T cells (Treg cells) are part of the system of checks and balances that prevents the immune response from going overboard and causing autoimmune disease. Although critically important for shaping the immune response and maintaining self-tolerance, how they hold on to their immune-suppressive powers had remained unclear.

17 Jun 2015

Regulatory T cells critical for the immune system's ability to fight off future pathogen attacks

Just as militaries need to have trained, experienced soldiers ready for future wars, making sure that the immune system has enough battle-ready T cells on hand is important for fast-acting, more effective vaccines, according to Penn State researchers.

17 Jun 2015

Breakthrough discovery on element transformation could lead to new way for treating cancer with radiation

Chemists at Tufts University's School of Arts and Sciences, collaborating with PerkinElmer and UCL (University College London), have witnessed atoms of one chemical element morph into another for the first time ever -- a feat that produced an unexpected outcome that could lead to a new way to safely treat cancer with radiation.

17 Jun 2015

Nanoplatform technology that detects early stages of cancer receives U.S. patent

A U.S. patent has been awarded to a Kansas State University technology that quickly detects the early stages of cancer before physical symptoms ever appear.

17 Jun 2015

Experts review strategies that may help improve adoptive cell immunotherapy for treating cancer

In a special issue of Immunotherapy, leading experts provide in-depth review of innovative strategies that may further the success of adoptive cell immunotherapy as a cancer treatment. Adoptive cell immunotherapy (ACT) has proven successful in clinical trials against certain types of melanoma and leukemia. The journal reviews new strategies to address the challenges of extending these effects to a wider range of tumor types.

17 Jun 2015

Scientists identify two new key players involved in development of prostate cancer

Understanding how a normal healthy cell turns into a cancerous one is our best bet yet for beating the disease. It will help better diagnose the cancer type, and enable the development of more effective, and less toxic therapies. But cells have evolved all sorts of sophisticated ways to become cancerous, and identifying the molecules involved and how they function in each type of cancer is a major undertaking.

16 Jun 2015

PNP Therapeutics granted FDA orphan drug designation for Gedeptin

PNP Therapeutics Inc. announced today the Food and Drug Administration has granted orphan drug status to Gedeptin, the Company's lead product candidate (adenoviral vector expressing E. coli purine nucleoside phosphorylase gene) for the intratumoral treatment of anatomically accessible oral and pharyngeal cancers, including cancers of the lip, tongue, gum, floor of mouth, salivary gland and other oral cavities.

16 Jun 2015

Apexigen initiates APX005M Phase 1 clinical trial in adults with solid tumors

Apexigen, Inc., a biopharmaceutical company discovering and developing innovative antibody drugs for the treatment of cancer and other life-threatening diseases, announced today the initiation of a Phase 1 clinical trial of APX005M, the company's lead proprietary anticancer program.

16 Jun 2015

OncoSec enrolls first patient in Phase II trial of ImmunoPulse IL-12 for treatment of HNSCC

OncoSec Medical Inc., a company developing DNA-based intratumoral cancer immunotherapies, announced today that the company has enrolled the first patient into OMS-I130, a Phase II clinical trial of ImmunoPulse IL-12 in patients with treatment-refractory, metastatic and unresectable squamous cell carcinoma of the head and neck (HNSCC).

16 Jun 2015

Tumor News and Research

Study demonstrates potential of new approach for sorting out BRCA1 gene variants

Florida Institute finalizes funding agreement with TransGenex Nanobiotech

Scientists reveal new combination method that efficiently destroys cancer cells

Value of Colorectal Cancer therapeutics market expected to increase $9.4 billion by 2020

NIBIB-funded researcher develops new technique for tissue analysis

Researchers highlight important factors that impact early-stage breast cancer patients' access to BCT

Johns Hopkins researchers develop new imaging technology to help remove brain tumors safely

Melanoma patients with high levels of H2A.Z.2 protein less likely to survive

Canadian and Israeli researchers meet to discuss underlying mechanisms that drive pancreatic cancer

Loyola tests new combination treatment for people living with cancer that has spread to spine

RPCI receives NCI grant to continue research program on photodynamic therapy for head and neck cancers

La Jolla Institute researchers identify molecular pathway that maintains Treg cells' function

Regulatory T cells critical for the immune system's ability to fight off future pathogen attacks

Breakthrough discovery on element transformation could lead to new way for treating cancer with radiation

Nanoplatform technology that detects early stages of cancer receives U.S. patent

Experts review strategies that may help improve adoptive cell immunotherapy for treating cancer

Scientists identify two new key players involved in development of prostate cancer

PNP Therapeutics granted FDA orphan drug designation for Gedeptin

Apexigen initiates APX005M Phase 1 clinical trial in adults with solid tumors

OncoSec enrolls first patient in Phase II trial of ImmunoPulse IL-12 for treatment of HNSCC

Exploring the G:Box and for high-quality imaging

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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