Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Genetic mechanisms could serve as a road map for screening new drugs to prolong healthy lifespan

The discovery in the 1990s that a mutation in a single gene of an experimental worm could double its lifespan set off a stampede of research on the molecular biology of aging and triggered hopes that drug therapies or other interventions could be developed to extend healthy human lifespan. But as is often the case in science, the genetic regulation of aging is more complicated than it first appeared.

10 Oct 2019

Scientists discover new patterns in the evolution of the influenza virus

Researchers from Skoltech have found that the devious influenza virus is capable of new patterns of evolution and mutation in order to escape treatment with the currently available drugs and prevention with the currently available vaccines. This discovery however could help researchers predict the potential mutations in the genome of the virus and ultimately help them develop and design more effective vaccines against influenza.

9 Oct 2019

Cholera pathogen can acquire large stretches of genetic material from neighboring bacteria

In 2015, EPFL researchers led by Melanie Blokesch published a seminal paper in Science showing that the bacterium responsible for cholera, Vibrio cholerae, uses a spring-loaded spear to literally stab neighboring bacteria and steal their DNA.

8 Oct 2019

Biology and computers meld to help understand how breast cancer develops

Among the most deadly killers in the area of cancer, breast cancer is also extremely difficult to treat, once it has spread to the bones. Not only does it metastasize rapidly, but it comprises a variety of cell types and also depends on the input from many other non-breast cells during the initiation, growth and spread of the cancer. This complexity makes it more difficult to develop targeted therapies in this condition.

8 Oct 2019

New patterns discovered in the evolution of influenza virus

Skoltech scientists discovered new patterns in the evolution of the influenza virus. This may help predict mutations in the viral genome and ultimately help design better vaccines.

8 Oct 2019

GW researchers show connection between bacteria in the microbiome and colon cancer

A mutant protein found in humans with colon cancer blocks a pathway that regulates proliferation and expansion of cells, increasing amounts of bacterial species associated with the development of colon cancer.

4 Oct 2019

NUS researcher invents novel transfection technique to deliver DNA into immune cells

Immunotherapy is a promising cancer treatment that uses genetically modified immune cells to fight cancer. It can be used as a primary treatment or in combination with other treatments such as radiation and chemotherapy to slow down or stop the growth of cancer cells and prevent them from spreading to other parts of the body.

4 Oct 2019

Brazilian researchers identify new species of parasite in fatal case of visceral leishmaniasis

Brazilian researchers believe they have identified in patients treated at the University Hospital (HU) in Aracaju, state of Sergipe, a new species of parasite that can cause a disease similar to visceral leishmaniasis but is resistant to the treatments currently available.

1 Oct 2019

Driving Adoption of Digital Pathology with Image Search

Driving adoption of digital pathology through the Scan Image Search from Huron Digital Pathology. Patrick Myles talks to the Dell Healthcare PowerChat Podcast.

From Huron Digital Pathology 1 Oct 2019

Mount Sinai researchers receive NIH award to develop universal flu vaccine

Researchers at the Icahn School of Medicine at Mount Sinai have received a contract award of up to $132 million from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH), as part of a new Collaborative Influenza Vaccine Innovation Centers (CIVICs) program to further develop the universal flu vaccine.

1 Oct 2019

NAU researchers aim to find microbial link between two common respiratory diseases

Asthma and chronic rhinosinusitis- sinus inflammation that lasts for at least three months- are serious and costly diseases, and both are on the rise. According to the American Academy of Allergy, Asthma and Immunology, CRS affects up to 16 percent of the U.S. adult population and eats up a staggering 5 percent of the country's health care budget each year.

27 Sep 2019

Russian researchers come up with faster method to discover antibiotics

Russian biochemists have identified a promising new class of antibiotics. Having studied over 125,000 molecules, they found that 2-pyrazol-1-yl-thiazole derivatives exhibit antibacterial properties.

26 Sep 2019

Scientists use new single-cell genetic technique to tackle potential drug resistance

Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor's potential resistance to a drug, and then identified a drug combination that reversed that resistance.

25 Sep 2019

Openspecimen chosen to manage ARTB's biospecimen library

The Auckland Region Tissue Bank is a critical component in New Zealand’s medical research infrastructure. As a central facility for storing blood and tissue samples, they have a library that could hold the secrets to unlocking cures for existing and future chronic diseases and illnesses.

25 Sep 2019

Scientists move one step closer to discovering the causes of immune diseases

Scientists are one step closer to discovering the causes of immune diseases such as asthma, multiple sclerosis and arthritis

23 Sep 2019

African bacterium resists almost all drugs

It looks like it’s time to pay the piper. The first extensively drug-resistant (XDR) strain of Salmonella typhimurium, called ST313 sublineage II.1, has cropped up in the Democratic Republic of Congo (DRC). This fails to respond to any of the antibiotics that are commonly used in the DRC, except for ciprofloxacin. And to make things worse, one sample has been isolated that shows incomplete response even to this last drug.

22 Sep 2019

AMP announces recipients of 2019's Award for Excellence in Molecular Diagnostics

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostics professional society, today announced the recipients of this year's Award for Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership Award and Meritorious Service Award.

19 Sep 2019

Salmonella responsible for bloodstream infections in sub-Saharan Africa exhibits extensive drug resistance

The first extensively drug-resistant strains of Salmonella Typhimurium, a pathogen which is responsible for millions of bloodstream infections per year in sub-Saharan Africa, have been identified in the Democratic Republic of Congo.

19 Sep 2019

Study uncovers new factor in the development of childhood lymphoma

A study recently published in the renowned journal Blood, led by Kaan Boztug, Scientific Director of the St. Anna Children's Cancer Research Institute, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Adjunct Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and Associate Professor at the Medical University of Vienna, together with scientists from Israel, Germany, Turkey, Colombia, Argentina and the USA, investigated four patients from independent families with malignancy, autoimmunity and immunodeficiency.

19 Sep 2019

NMDAR receptor is responsible for breast-to-brain metastases, shows study

In 2018, breast cancer was the most common cancer in women worldwide, accounting for about a quarter of all reported cancers. One of the biggest problems with any type of cancer is metastasis; and when breast cancer metastasizes, the brain is a common destination.

19 Sep 2019

Bioinformatics News and Research

Further Reading

Genetic mechanisms could serve as a road map for screening new drugs to prolong healthy lifespan

Scientists discover new patterns in the evolution of the influenza virus

Cholera pathogen can acquire large stretches of genetic material from neighboring bacteria

Biology and computers meld to help understand how breast cancer develops

New patterns discovered in the evolution of influenza virus

GW researchers show connection between bacteria in the microbiome and colon cancer

NUS researcher invents novel transfection technique to deliver DNA into immune cells

Brazilian researchers identify new species of parasite in fatal case of visceral leishmaniasis

Driving Adoption of Digital Pathology with Image Search

Mount Sinai researchers receive NIH award to develop universal flu vaccine

NAU researchers aim to find microbial link between two common respiratory diseases

Russian researchers come up with faster method to discover antibiotics

Scientists use new single-cell genetic technique to tackle potential drug resistance

Openspecimen chosen to manage ARTB's biospecimen library

Scientists move one step closer to discovering the causes of immune diseases

African bacterium resists almost all drugs

AMP announces recipients of 2019's Award for Excellence in Molecular Diagnostics

Salmonella responsible for bloodstream infections in sub-Saharan Africa exhibits extensive drug resistance

Study uncovers new factor in the development of childhood lymphoma

NMDAR receptor is responsible for breast-to-brain metastases, shows study

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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