Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Deep learning helps determine a woman’s risk of breast cancer

A new deep learning model could more accurately predict a woman’s risk of developing breast cancer than current risk assessment tools.

27 Nov 2020

‘Molecular clock’ blood test could help identify actively growing tumors in metastatic breast cancer

A blood test to watch breast cancer’s ‘molecular clock’ could help track the growth of multiple tumors around the body and monitor how they are responding to treatment, new research suggests.

27 Nov 2020

Fruit fly study reveals the effects of microgravity on the heart

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that fruit flies that spent several weeks on the International Space Station (ISS)—about half of their lives—experienced profound structural and biochemical changes to their hearts.

25 Nov 2020

New drug lures stem cells to damaged tissue, improves treatment efficacy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a drug that can lure stem cells to damaged tissue and improve treatment efficacy--a scientific first and major advance for the field of regenerative medicine.

25 Nov 2020

Mother's protein found to be involved in genomic imprinting process

Mothers leave their mark on their children in many ways - and Australian researchers have discovered a protein called SMCHD1 is involved in this 'imprinting' process.

24 Nov 2020

Understanding biomolecular frustration could help design better drugs

Knowing precisely where proteins are frustrated could go a long way toward making better drugs.

23 Nov 2020

Compounds in traditional Chinese medicine herbs may inhibit SARS-CoV-2 infection

Using computational methods, a team of researchers identified three compounds in traditional Chinese medicine that could be used against SARS-CoV-2.

23 Nov 2020

Study addresses gap in the discovery of new antibiotics

University of Oklahoma researchers published an opinion article in the journal Nature Chemical Biology that addresses the gap in the discovery of new antibiotics.

20 Nov 2020

Advion announces appointment of Dr. Kaveh Kahen as new CEO David B. Patteson remains as group Chairman

Advion, Inc. announces that Dr. Kaveh Kahen will immediately become CEO of the Advion group. Dave Patteson, the prior Chairman and CEO of the group will remain as group Chairman.

From Advion 19 Nov 2020

Research on genetic heart disease uncovers new mechanism for heart failure

Research on genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy.

19 Nov 2020

Alzheimer's study shows tau protein changes according to dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

Raman microscopy-based approach uses gold nanoparticles for visualizing small-molecule drugs

Successful drug development has a significant impact on people's quality of life worldwide. Being able to track how molecules get into target cells, and observing what they do when they are inside, is key to identifying the best candidates.

18 Nov 2020

Natural products and herbal medicines show promise in fight against COVID-19

Researchers in China and the United States have called for more research into the potential prophylactic effects of natural products and herbal medicines on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and subsequent coronavirus disease 2019 (COVID-19).

17 Nov 2020

Targeting BCAP with new drugs could benefit people with inflammatory bowel disease

Managing the activity of the BCAP protein could help the body repair intestinal tissue from damage caused by inflammation, according to a new study led by experts at Cincinnati Children's.

17 Nov 2020

UCLA Health collaborates with Regeneron Genetics Center to bring genomic medicine to patients

UCLA Health has entered into a collaborative research agreement with the Regeneron Genetics Center (RGC) to provide whole exome sequencing for 150,000 UCLA Health patients.

16 Nov 2020

Weekly exercise linked to lower risk of Alzheimer's disease in patients with mild cognitive impairment

Exercising more than once per week is associated with a lower risk of developing Alzheimer's disease in patients with mild cognitive impairment, research published in the open access journal Alzheimer's Research and Therapy suggests.

12 Nov 2020

Return of mice to home cage evokes significant rise in dopamine release, shows study

By monitoring a well-replicated biomarker associated with reward, a study by neuroscientists from Florida Atlantic University provides evidence that the old adage, "There's no place like home," has its roots deep in the brain.

12 Nov 2020

StemBioSys and Cartox Announce Publication of Research Demonstrating CELLvo™ Matrix Plus Significantly Enhances the Functionality of hiPSC Cardiomyocytes

StemBioSys, Inc announced today the publication of research in Nature Scientific Reports demonstrating their latest CELLvo™ Matrix Plus findings.

From StemBioSys 12 Nov 2020

New Cambridge Centre aims to transform precision medicine and biomedical discoveries

A new center at the University of Cambridge, in collaboration with AstraZeneca and GSK, aims to use AI to make medical discoveries, accelerate the development of precision medicine and develop new treatments

12 Nov 2020

New Cambridge center aims to use AI to make medical discoveries, develop new treatments

A new centre at the University of Cambridge, in collaboration with AstraZeneca and GSK, aims to use AI to make medical discoveries, accelerate the development of precision medicine and develop new treatments.

11 Nov 2020

Drug Discovery News and Research

Further Reading

Deep learning helps determine a woman’s risk of breast cancer

‘Molecular clock’ blood test could help identify actively growing tumors in metastatic breast cancer

Fruit fly study reveals the effects of microgravity on the heart

New drug lures stem cells to damaged tissue, improves treatment efficacy

Mother's protein found to be involved in genomic imprinting process

Understanding biomolecular frustration could help design better drugs

Compounds in traditional Chinese medicine herbs may inhibit SARS-CoV-2 infection

Study addresses gap in the discovery of new antibiotics

Advion announces appointment of Dr. Kaveh Kahen as new CEO David B. Patteson remains as group Chairman

Research on genetic heart disease uncovers new mechanism for heart failure

Alzheimer's study shows tau protein changes according to dementia stage

Raman microscopy-based approach uses gold nanoparticles for visualizing small-molecule drugs

Natural products and herbal medicines show promise in fight against COVID-19

Targeting BCAP with new drugs could benefit people with inflammatory bowel disease

UCLA Health collaborates with Regeneron Genetics Center to bring genomic medicine to patients

Weekly exercise linked to lower risk of Alzheimer's disease in patients with mild cognitive impairment

Return of mice to home cage evokes significant rise in dopamine release, shows study

StemBioSys and Cartox Announce Publication of Research Demonstrating CELLvo™ Matrix Plus Significantly Enhances the Functionality of hiPSC Cardiomyocytes

New Cambridge Centre aims to transform precision medicine and biomedical discoveries

New Cambridge center aims to use AI to make medical discoveries, develop new treatments

ELRIG Drug Discovery: Poster Sessions eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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