Small Molecules News and Research

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Study uncovers complicated role of simple protein in spread of osteosarcoma

The investigation of a simple protein has uncovered its uniquely complicated role in the spread of the childhood cancer, osteosarcoma. It turns out the protein, called ezrin, acts like an air traffic controller, coordinating multiple functions within a cancer cell and allowing it to endure stress conditions encountered during metastasis.

7 Jul 2015

Blood-borne molecule promotes age-related cognitive decline

A blood-borne molecule that increases in abundance as we age blocks regeneration of brain cells and promotes cognitive decline, suggests a new study by researchers at UC San Francisco and Stanford School of Medicine.

7 Jul 2015

Sialic acid attached to brain cells may affect brain structure, cause neurological problems

New research from The Johns Hopkins University suggests that a molecule commonly found “decorating” brain cells in higher animals, including humans, may affect brain structure.

7 Jul 2015

Common arthritis drug could help to treat patients with blood cancers

Scientists at the University of Sheffield have discovered that a common drug given to arthritis sufferers could also help to treat patients with blood cancers.

7 Jul 2015

Sialic acid may play significant role in certain brain disorders

A new report published in the July 2015 issue of The FASEB Journal suggests that a common molecule found in higher animals, including humans, affects brain structure. This molecule may play a significant role in how brain cells communicate, possibly shedding light on the underlying causes of certain brain disorders.

1 Jul 2015

Enhancements to Reaxys Medicinal Chemistry address workflow, data challenges of early drug discovery

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced enhancements to Reaxys Medicinal Chemistry that address the critical workflow and data challenges of early drug discovery.

30 Jun 2015

Three National Laureates selected for 2015 Blavatnik National Awards for Young Scientists

A chemist who has made important discoveries in both the human brain and sustainable energy, a neurosurgeon who has done pioneering work mapping the "blueprint" of how humans speak and hear, and a computer scientist who has changed our understanding of the capacity of wireless networks are the three winners of the 2015 Blavatnik National Awards for Young Scientists.

30 Jun 2015

Global GBM therapeutics market to expand at CAGR of 10.9% to $623 million by 2020

According to analysis from business intelligence provider GBI Research - Glioblastoma Multiforme Therapeutics in Major Developed Markets to 2020 - the value of the global Glioblastoma Multiforme (GBM) treatment market will expand at a rapid Compound Annual Growth Rate (CAGR) of 10.9%, from $301 million in 2013 to $623 million by 2020.

29 Jun 2015

Diet, acidity of urine may influence susceptibility to urinary tract infections

The acidity of urine -- as well as the presence of small molecules related to diet -- may influence how well bacteria can grow in the urinary tract, a new study shows. The research, at Washington University School of Medicine in St. Louis, may have implications for treating urinary tract infections, which are among the most common bacterial infections worldwide.

26 Jun 2015

UAlberta partnership could transform cancer treatment, improve patient outcomes

A multimillion dollar research partnership announced today at the University of Alberta is giving a "dream team" of researchers the opportunity to potentially transform cancer treatment and better patient outcomes.

25 Jun 2015

TSRI scientists devise powerful set of chemical methods to explore protein biology

Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins.

22 Jun 2015

UW researchers identify how plants arrange cellular structures on their surface

In the age of tablet computers and smart phones, it's easy to feel inundated and overloaded by information. But on a cellular level, this bombardment is business as usual, and a team of University of Washington researchers has identified a mechanism that some plant cells use to receive complex and contradictory messages from their neighbors.

19 Jun 2015

Scientists reveal new combination method that efficiently destroys cancer cells

Scientists at the Institut Pasteur and Inserm have successfully increased the infiltration of immune cells into tumors, thus inducing the immune system to block tumor growth. In an article published in Nature Immunology, the scientists show that, in combination with existing immunotherapies, this process efficiently destroys cancer cells.

18 Jun 2015

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

CQDM and Ontario Centres of Excellence will fund five highly innovative and unconventional game-changing research and development projects to accelerate drug discovery in the Quebec-Ontario Life Sciences Corridor. Partners are granting $1.5M to Quebec-based and, for the first time, Ontario-based researchers thanks to the partnership with OCE through CQDM's 2014 Explore Program, one of CQDM's flagship programs focusing on early concept validation of cutting-edge technologies that address the most crucial needs in drug discovery and development.

17 Jun 2015

Experimental drug improves failing heart's function

An experimental drug improves the ability of heart muscle cells damaged by heart failure to pump blood, according to the results of a study led by Icahn School of Medicine at Mount Sinai researchers and published online today in Nature Communications.

14 Jun 2015

ITbM researchers find new molecules that change circadian rhythm in mammals

A team of chemists and biologists at the Institute of Transformative Bio-Molecules, Nagoya University have succeeded in finding new molecules that change the circadian rhythm in mammals by applying synthetic chemistry methods, which makes use of highly selective metal catalysts.

10 Jun 2015

UC Santa Cruz-led study offers new insights into molecular mechanisms of biological clock

A new study led by UC Santa Cruz researchers has found that a protein associated with cancer cells is a powerful suppressor of the biological clock that drives the daily ("circadian") rhythms of cells throughout the body.

3 Jun 2015

MedImmune, AstraZeneca present encouraging results from new combination-focused immuno-oncology portfolio at ASCO 2015

AstraZeneca and MedImmune, the company’s global biologics research and development arm, today presented encouraging results from their novel combination-focused immuno-oncology portfolio at the American Society of Clinical Oncology (ASCO) Annual Meeting 2015.

2 Jun 2015

Amgen creates catalog of qualified tools and reagents to advance basic discoveries in biology

Amgen today announced the creation of a catalog of qualified tools and reagents available to academic institutions to help further research and advance basic discoveries in biology, as well as deepen relationships with academic institutions.

29 May 2015

Researchers find weak spot in some antibiotic-resistant bacteria

Using a complex modeling program that helps analyze the physical dynamics of large, structurally complex protein molecules, a research team has made progress towards finding a weak spot in the architecture of a group of enzymes that are essential to antibiotic resistance in a number of bacteria.

29 May 2015

Small Molecules News and Research

Study uncovers complicated role of simple protein in spread of osteosarcoma

Blood-borne molecule promotes age-related cognitive decline

Sialic acid attached to brain cells may affect brain structure, cause neurological problems

Common arthritis drug could help to treat patients with blood cancers

Sialic acid may play significant role in certain brain disorders

Enhancements to Reaxys Medicinal Chemistry address workflow, data challenges of early drug discovery

Three National Laureates selected for 2015 Blavatnik National Awards for Young Scientists

Global GBM therapeutics market to expand at CAGR of 10.9% to $623 million by 2020

Diet, acidity of urine may influence susceptibility to urinary tract infections

UAlberta partnership could transform cancer treatment, improve patient outcomes

TSRI scientists devise powerful set of chemical methods to explore protein biology

UW researchers identify how plants arrange cellular structures on their surface

Scientists reveal new combination method that efficiently destroys cancer cells

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

Experimental drug improves failing heart's function

ITbM researchers find new molecules that change circadian rhythm in mammals

UC Santa Cruz-led study offers new insights into molecular mechanisms of biological clock

MedImmune, AstraZeneca present encouraging results from new combination-focused immuno-oncology portfolio at ASCO 2015

Amgen creates catalog of qualified tools and reagents to advance basic discoveries in biology

Researchers find weak spot in some antibiotic-resistant bacteria

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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