Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

COVID-19 and immunodeficiency

COVID-19 disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a highly infectious disease. As of today, over 170,000 people worldwide have succumbed to the infection. Reports have shown that some comorbidities and illnesses raise the risk of getting infected and also influence the severity of the disease. Having a compromised immune system can also drastically raise the risk of getting COVID-19.

21 Apr 2020

ACE2-TMPRSS2 profiling indicates tissue vulnerability to SARS-CoV-2 infection

A new study published in April 2020 on the preprint server bioRxiv reports that the different levels of susceptibility of various organs to viral attack by the SARS-CoV-2 virus causing the huge pandemic of COVID-19 sweeping around the world can be predicted from the level of expression of two molecules, the ACE2 receptor, and the TMPRSS2 protein.

20 Apr 2020

Do ACE inhibitors increase SARS-CoV-2 binding to ACE2?

The COVID-19 pandemic has forced clinicians and academicians to intensive research to find evidence for many conventional therapies. A new round-up editorial published in the journal Cardiovascular Research in April 2020 summarizes the current clinical grounds for and against the use of the commonly used angiotensin axis inhibitors in patients with COVID-19.

20 Apr 2020

New tool predicts risk of admission to long-term care home and death for dementia patients

A new tool that predicts risk of death and admission to a long-term care facility for patients with dementia may help conversations between health care providers, patients and their families, according to new research in CMAJ.

20 Apr 2020

How climate change is putting doctors in the hot seat

A 4-year-old girl was rushed to the emergency room three times in one week for asthma attacks.

20 Apr 2020

Poorer regions in the Philippines have more COVID-19 cases

The coronavirus disease (COVID-19) has dramatically affected European countries and the United States, reporting the highest number of confirmed cases. In Asia, though the number of infections gradually increases, some countries have reported high death rates, including Indonesia and the Philippines.

20 Apr 2020

Sewage study finds link between rates of sepsis in UK and presence of E. coli in the community

A study suggests rates of E. coli related sepsis in the UK is linked to community E. coli levels determined by sewage presence.

17 Apr 2020

Study highlights gap between men and women who suffer from heart attack

Women are more likely to die after a heart attack than men because they are often not prescribed the drugs they need. That's the result of research presented today on ACVC Essentials 4U, a scientific platform of the European Society of Cardiology (ESC).

17 Apr 2020

Trial to evaluate how blood pressure medications affect outcomes among COVID-19 patients

A new trial led by the Perelman School of Medicine at the University of Pennsylvania will evaluate whether the use of medications to treat high blood pressure affect outcomes among patients who are prescribed the medication and hospitalized with COVID-19.

16 Apr 2020

A 'toolbox' for biomarker discovery of urological cancers

Researchers from Ghent University, Belgium, together with researchers from the University of Turku, Finland, have developed a new method for biomarker discovery of urological cancers.

16 Apr 2020

Regular exercise may reduce risk of deadly complication in patients with COVID-19

Regular exercise may reduce the risk of acute respiratory distress syndrome, a major cause of death in patients with the COVID-19 virus, a top exercise researcher reports.

15 Apr 2020

Coronavirus able to survive near boiling point of water, study shows

A startling paper by a team of French scientists published in the preprint journal bioRxiv in April 2020 suggests that the novel coronavirus is capable of surviving at high temperatures. This could mean that laboratory technicians handling the virus are at danger of infection.

15 Apr 2020

China with the world: COVID-19 experts dialogues - the 2nd talk transcript

Q: Starting from the patient admission to the hospital, what is your rule for ventilation? Do you start from HFNC, CPAP, NIV or go directly to intubation and invasive ventilation when the conventional oxygen therapy fails?

From Mindray 15 Apr 2020

CRISPR may help in kidney-transplants by detecting viruses

An exciting new study published in the journal Nature Biomedical Engineering in April 2020 reports excellent results with a new test for two common viruses that infect kidney transplant patients. The levels of these viruses shoot up during the acute phase of rejection.

13 Apr 2020

Molecular pathway responsible for TNBC's progression and spread identified

Immunotherapies have revolutionized treatment for people with a variety of cancers. But when given to those with triple-negative breast cancer, a particularly aggressive form of the disease, less than 20% respond.

13 Apr 2020

Newer therapies may benefit patients with type 2 diabetes and coronary artery disease

Type 2 diabetes affects treatment options for patients who have both coronary artery disease and T2D, according to a new American Heart Association Scientific Statement, published today in the Association's flagship journal Circulation.

13 Apr 2020

People with type 2 diabetes and heart disease may benefit from newer therapies

Type 2 diabetes (T2D) may affect treatment options for patients who have both coronary artery disease (CAD) and T2D.

13 Apr 2020

Where cancers spread can give specific insights on disease traits

Kidney cancers that metastasize to the pancreas have a fundamentally different biology from those that metastasize elsewhere, with characteristics that can influence successful treatment, a study led by investigators with the UT Southwestern Kidney Cancer Program suggests.

12 Apr 2020

ERA-EDTA creates European database of dialysis, transplanted patients with COVID-19

The ERA-EDTA has created a European database that collects granular individual data of dialysis patients and transplanted patients with COVID-19.

9 Apr 2020

Hypertensive patients on ACE inhibitors and angiotensin receptor blockers may have improved COVID-19 prognosis

Emerging concerns that common antihypertensive treatment approaches with angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) – jointly known as renin-angiotensin-aldosterone system (RAAS) inhibitors – may exert a negative effect in COVID-19 patients are not grounded in scientific evidence, as reported by researchers in a recent review article published in Mayo Clinic Proceedings journal.

9 Apr 2020