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Genetically modified Salmonella can help kill cancer cells

A new study has demonstrated that genetically modified Salmonella can be used to kill cancer cells. The study is published in this week's issue of mBio, an American Society for Microbiology online-only, open access journal.

15 Apr 2015

U-M researchers make major breakthrough in diagnosing, treating prostate cancer

University of Michigan researchers have discovered a biomarker that may be a potentially important breakthrough in diagnosing and treating prostate cancer.

13 Apr 2015

MSK begins CAR T cell clinical trial for children with relapsed or treatment-resistant ALL

Researchers from Memorial Sloan Kettering Cancer Center are pioneering a new groundbreaking clinical trial for children and young adults with relapsed or treatment-resistant acute lymphocytic leukemia (ALL) by using one of the most promising methods of cancer treatment today, chimeric antigen receptor (CAR) T cells.

12 Apr 2015

Penn researchers receive 2015 Vaccine Industry Excellence Award

The laboratory of David Weiner, PhD, a professor of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania, received the 2015 Vaccine Industry Excellence Award for Best Academic Research Team, at the World Vaccine Congress in Washington, DC this week.

12 Apr 2015

New study could hold key to control growth of cancer cells

A new study by researchers at the Technion-Israel Institute of Technology could hold a key to control cancer cell growth and development. In a paper published yesterday in CELL, the team reports on the discovery of two cancer-suppressing proteins.

12 Apr 2015

New combination therapy holds promise for treating HER2-positive breast cancer

Resistance to therapy is a major problem in the cancer field. Even when a treatment initially works, the tumors often find ways around the therapy.

10 Apr 2015

Subpopulation of tumor cells make melanoma aggressive

KU Leuven researchers have zeroed in on what makes cancer cells in melanoma so aggressive. They also succeeded in taming the effect in cell cultures.

10 Apr 2015

Vascular mimicry can spread breast cancer to other sites

Imitation may be the sincerest form of flattery, but it can also have deadly consequences, at least when it comes to tumor cells.

10 Apr 2015

Stem cell disease model reveals how tumor suppressor may drive bone cancer

Using induced pluripotent stem cells (iPSCs), a team led by Mount Sinai researchers has gained new insight into genetic changes that may turn a well known anti-cancer signaling gene into a driver of risk for bone cancers, where the survival rate has not improved in 40 years despite treatment advances.

10 Apr 2015

Scientists identify chemical compounds that block cancer-causing oncoprotein

A team of scientists at the University of Kansas has pinpointed six chemical compounds that thwart HuR, an "oncoprotein" that binds to RNA and promotes tumor growth.

10 Apr 2015

People with high-risk tumors containing BRAF or NRAS gene mutations have lower survival rates

Researchers from the UNC Lineberger Comprehensive Cancer Center analyzed hundreds of melanoma samples to find out if two genetic mutations more commonly found in melanoma tumors were associated with lower survival rates in patients.

9 Apr 2015

BioTek to exhibit at American Association for Cancer Research 2015

BioTek Instruments will demonstrate their latest microplate-based imaging, detection and liquid handling solutions for cancer research at the AACR Annual Meeting to be held April 18-22 in Philadelphia, Pennsylvania.

9 Apr 2015

Pharmacyclics announces positive results from IMBRUVICA Phase II study in WM patients

Pharmacyclics, Inc. today announced longer-term data from a Phase II investigator-initiated study showing Waldenstrom's macroglobulinemia (WM) patients treated with IMBRUVICA (ibrutinib) experienced sustained disease control with an overall response rate (ORR) of 91% after a median of 19.1 months of treatment and a 2-year overall survival (OS) rate of 95%.

9 Apr 2015

USPTO issues Cardio3 BioSciences Notice of Allowance for patent covering CAR-expressing TCR-deficient T-Cells

Cardio3 BioSciences, a leader in engineered cell therapies with clinical programs initially targeting indications in cardiovascular disease and oncology, today announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for a significant patent application covering T-Cell receptor-deficient T-Cells which are engineered to express a chimeric antigen receptor.

9 Apr 2015

UQDI reveals that Anisina drug can kill melanoma cells

US-Australian drug discovery company, Novogen, today announced that studies conducted at The University of Queensland Diamantina Institute revealed that experimental drug, Anisina, killed melanoma cells irrespective of their mutational status.

9 Apr 2015

MammaPrint 70-gene breast cancer recurrence assay recommended in Germany’s AGO Guidelines

Agendia, a leading molecular diagnostics company that develops and markets genomic diagnostic products, announced at the St. Gallen International Breast Cancer Conference that new guidelines of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) recommend the MammaPrint® 70-gene breast cancer recurrence assay in Germany’s 2015 guidelines for early-stage invasive breast cancer.

9 Apr 2015

Study suggests that pancreatic cancers harbor genetic alterations

A genetic analysis led by UT Southwestern Medical Center researchers suggests that most pancreatic cancers harbor genetic alterations that could be targeted by existing drugs, using their genetic features as a roadmap for treatment. The findings support a precision approach to treating pancreatic cancer, the fourth most deadly cancer for both men and women.

9 Apr 2015

Researchers link loss of WAVE1 gene to lethal form of prostate cancer

Researchers at Upstate Medical University and Harvard University have linked the loss of key gene, WAVE1, to a lethal form of prostate cancer, according to a study published in the journal Oncotarget.

9 Apr 2015

Neuro-oncology researchers identify mechanism responsible for tumor cell invasion in glioblastoma

A neuro-oncology research team at Dartmouth's Norris Cotton Cancer Center, led by the Director Mark A. Israel, MD with first author Gilbert J. Rahme, PhD, recently identified the transcription factor Id4 as a suppressor of tumor cell invasion in glioblastoma.

9 Apr 2015

Biologists discover vulnerability of brain cancer cells

Biologists at MIT and the Whitehead Institute for Biomedical Research have discovered a vulnerability of brain cancer cells that could be exploited to develop more-effective drugs against brain tumors.

9 Apr 2015

Tumor News and Research

Genetically modified Salmonella can help kill cancer cells

U-M researchers make major breakthrough in diagnosing, treating prostate cancer

MSK begins CAR T cell clinical trial for children with relapsed or treatment-resistant ALL

Penn researchers receive 2015 Vaccine Industry Excellence Award

New study could hold key to control growth of cancer cells

New combination therapy holds promise for treating HER2-positive breast cancer

Subpopulation of tumor cells make melanoma aggressive

Vascular mimicry can spread breast cancer to other sites

Stem cell disease model reveals how tumor suppressor may drive bone cancer

Scientists identify chemical compounds that block cancer-causing oncoprotein

People with high-risk tumors containing BRAF or NRAS gene mutations have lower survival rates

BioTek to exhibit at American Association for Cancer Research 2015

Pharmacyclics announces positive results from IMBRUVICA Phase II study in WM patients

USPTO issues Cardio3 BioSciences Notice of Allowance for patent covering CAR-expressing TCR-deficient T-Cells

UQDI reveals that Anisina drug can kill melanoma cells

MammaPrint 70-gene breast cancer recurrence assay recommended in Germany’s AGO Guidelines

Study suggests that pancreatic cancers harbor genetic alterations

Researchers link loss of WAVE1 gene to lethal form of prostate cancer

Neuro-oncology researchers identify mechanism responsible for tumor cell invasion in glioblastoma

Biologists discover vulnerability of brain cancer cells

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