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Study shows how 3D organization of genetic material helps perpetuate the species

From fathers to children, the delivery of hereditary information requires the careful packing of DNA in sperm. But just how nature packages this DNA to prepare offspring isn't clear.

19 Feb 2019

Harnessing the evolutionary games played by cancer cells to advance therapies

Despite rapid advances in targeted therapies for cancer, tumors commonly develop resistance to treatment. When resistance emerges, tumor cells continue to grow unchecked, despite all attempts to slow cancer progression.

19 Feb 2019

Researchers identify suicide toxin in the bacteria responsible for tuberculosis

The bacteria responsible for tuberculosis can be killed by a toxin they produce unless it is neutralized by an antidote protein. The European team of scientists behind this discovery is coordinated by researchers from the Institute of Pharmacology and Structural Biology and the European Molecular Biology Laboratory.

18 Feb 2019

New protocol can help identify febrile infants at low risk for serious bacterial infections

A national research team led by UC Davis Health clinicians and researchers from the University of Michigan, Nationwide Children's Hospital and Columbia University, has derived and validated a new protocol for emergency departments that can determine which infant patients with fevers, age 60 days or younger, are at low risk of significant bacterial infections.

18 Feb 2019

Using light-based method for production of pharmaceutical molecules

Photoelectrochemical cells are widely studied for the conversion of solar energy into chemical fuels. They use photocathodes and photoanodes to "split" water into hydrogen and oxygen respectively.

18 Feb 2019

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.

18 Feb 2019

Customizing the Cellular Microenvironment to Improve Physiological Relevance

An interview with Marie-Charlotte Manus, discussing a new technology called PRIMO that improves the physiological relevance of cells in culture.

From Alveole 18 Feb 2019

Heavy smoking could lead to vision loss, study finds

Smoking more than 20 cigarettes a day can damage your vision, a study co-authored by a Rutgers researcher finds.

18 Feb 2019

Children from homes with flame-retardant sofa have high SVOC concentration in their blood

Children living in homes with all vinyl flooring or flame-retardant chemicals in the sofa have significantly higher concentrations of potentially harmful semi-volatile organic compounds in their blood or urine than children from homes where these materials are not present, according to a new Duke University-led study.

18 Feb 2019

New PET/CT tracer shows high detection rate for diagnosis of acute venous thromboembolism

A first-in-human study featured in the February issue of The Journal of Nuclear Medicine reports that the novel positron emission tomography/computed tomography tracer 18F-GP1 showed excellent image quality and a high detection rate for the diagnosis of acute venous thromboembolism.

18 Feb 2019

MUSC researchers discover new mechanism for a class of anti-cancer drugs

Researchers at the Medical University of South Carolina reveal a novel binding site for a class of anti-cancer drugs known as E1 inhibitors. This finding could lead to the design of more efficient E1 inhibitors.

15 Feb 2019

Blood clot discovery could lead to development of better treatments for blood diseases

Scientists have discovered new ways in which the body regulates blood clots, in a discovery which could one day lead to the development of better treatments that could help prevent and treat conditions including heart diseases, stroke and vascular dementia.

15 Feb 2019

Newly developed stem cell technologies show promise for treating PD patients

Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

15 Feb 2019

Moffitt researchers shed light on how CAR T cells function mechanistically

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells.

15 Feb 2019

Platinum nanoparticles show selective toxicity against liver cancer cells

In recent years, the number of targeted cancer drugs has continued to rise. However, conventional chemotherapeutic agents still play an important role in cancer treatment.

15 Feb 2019

Lifetime adversity, increased neural processing during trauma combine to intensify core PTSD symptoms

Lifetime adversity and increased neural processing during a traumatic event combine to increase the frequency of intrusive traumatic memories and the distress they cause, according to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

14 Feb 2019

Exposure to chemical in weedkiller Roundup raises risk of some cancers, study finds

Exposure to glyphosate--the world's most widely used, broad-spectrum herbicide and the primary ingredient in the weedkiller Roundup--increases the risk of some cancers by more than 40 percent, according to new research from the University of Washington.

14 Feb 2019

Laboratory News and Research

Study shows how 3D organization of genetic material helps perpetuate the species

Harnessing the evolutionary games played by cancer cells to advance therapies

Researchers identify suicide toxin in the bacteria responsible for tuberculosis

New protocol can help identify febrile infants at low risk for serious bacterial infections

Using light-based method for production of pharmaceutical molecules

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

Customizing the Cellular Microenvironment to Improve Physiological Relevance

Heavy smoking could lead to vision loss, study finds

Children from homes with flame-retardant sofa have high SVOC concentration in their blood

New PET/CT tracer shows high detection rate for diagnosis of acute venous thromboembolism

MUSC researchers discover new mechanism for a class of anti-cancer drugs

Blood clot discovery could lead to development of better treatments for blood diseases

Newly developed stem cell technologies show promise for treating PD patients

Moffitt researchers shed light on how CAR T cells function mechanistically

Platinum nanoparticles show selective toxicity against liver cancer cells

Lifetime adversity, increased neural processing during trauma combine to intensify core PTSD symptoms

Exposure to chemical in weedkiller Roundup raises risk of some cancers, study finds

Social threat learning has a strong effect on our decision-making

Innovative new software could help prevent incidence of arrhythmia

New research explains presence of ‘natural’ magnetism in human cells

Viva Saliva Book: The ultimate guide to saliva Book preview Download eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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