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New findings could pave way to develop drug therapies for necrosis-related diseases

Strokes, heart attacks and traumatic brain injuries are separate diseases with certain shared pathologies that achieve a common end - cell death and human injury due to hypoxia, or lack of oxygen.

9 Feb 2015

Salicylates drugs reduce proliferation, viability of cultured vestibular schwannoma cells

Researchers from Massachusetts Eye and Ear and the Harvard Medical School/ Massachusetts Institute of Technology's Program in Speech and Hearing Bioscience and Technology have demonstrated that salicylates, a class of non-steroidal inflammatory drugs (NSAIDs), reduced the proliferation and viability of cultured vestibular schwannoma cells that cause a sometimes lethal intracranial tumor that typically causes hearing loss and tinnitus.

9 Feb 2015

New compound may lead to development of potential therapeutics for neuropathic pain

A new compound discovered by a team of UC Davis investigators has potent actions against production of a chemical that which is implicated in the development of chronic pain following a peripheral nerve injury in the spinal cord.

7 Feb 2015

Chinese researchers achieve major breakthrough in nano-carrier drugs for pancreatic cancer

At the "Symposium on the Application of Genetic Testing in Individualized Diagnosis and Treatment of Tumor" recently held in Tianjin, the research team led by Professor Hao Jihui of the Pancreas Oncology Department of Tianjin Medical University Cancer Hospital announced that they had achieved a major breakthrough in the field of nano-carrier drugs for pancreatic cancer.

6 Feb 2015

New study provides better understanding of how stem cells give rise to tumors

Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered a precise stem cell signaling process that can lead to intestinal tumors if disrupted. The findings add to our understanding of how stem cells give rise to tumors and identify specific stem cell molecules that may be targeted to prevent the onset, progression, and recurrence of intestinal cancers.

6 Feb 2015

Chemotherapy or immunosuppressive treatment may reactivate HBV

Individuals previously infected with the hepatitis B virus (HBV) who receive chemotherapy or immunosuppressive treatment may be at risk of reactivating the disease according to a summary of report from the Emerging Trends Conference, "Reactivation of Hepatitis B," and published in Hepatology, a journal of the American Association for the Study of Liver Diseases.

6 Feb 2015

Prostate cancer patients with detectable post-operative PSA should receive more aggressive treatment

Prostate cancer patients with detectable prostate specific antigen (PSA) following radical prostatectomy should receive earlier, more aggressive radiation therapy treatment, according to a study published in the February 1, 2015 issue of the International Journal of Radiation Oncology * Biology * Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology.

6 Feb 2015

ECOG-ACRIN Cancer Research Group opens clinical trial for women with newly diagnosed DCIS

In direct response to recommendations made by a National Institutes of Health scientific consensus panel, the ECOG-ACRIN Cancer Research Group announced today the opening of E4112, a clinical trial for women with newly diagnosed ductal carcinoma in situ (DCIS) of the breast who, together with their doctors, will use the results of a magnetic resonance imaging (MRI) exam to determine whether to undergo a lumpectomy or a mastectomy.

6 Feb 2015

New NIEHS grants to support independent biomedical research

New grants totaling $3 million will go to six outstanding early-career scientists, bridging a funding gap to independent biomedical research. The National Institute of Environmental Health Sciences, part of the National Institutes of Health, created the award to encourage early stage researchers who want to discover how our environment influences human health.

6 Feb 2015

New study links cell communication pathway to common brain tumors found in children

A new study by Johns Hopkins researchers links a well-known cell communication pathway called Notch to one of the most common -- but overall still rare -- brain tumors found in children.

6 Feb 2015

Crown Bioscience, NRCMM partner to develop new immune-oncology experimental cancer models

Crown Bioscience, Inc., a leading global drug discovery and development service company with its R&D centers across the globe has announced that a new partnership agreement has been reached with the National Resource Center for Mutant Mice and its commercial branch Nanjing Biotech Innovation Corporation, in Nanjing, Jiangsu Province, China.

6 Feb 2015

Antibodies used in research lab should be made by recombinant DNA technology, say authors

Antibodies are now established as therapeutics and indispensable in the research lab. In con-trast to high-quality therapeutics, commercial antibodies used in research often do not proper-ly function, as an international group of authors around Andreas Plückthun of UZH have warned.

5 Feb 2015

Scientists investigate how T cells in colorectal tumors actively fight cancer

In recent years, a standard follow-up to colorectal cancer surgery has been to analyze the tumor tissue for the presence of immune cells. Finding high quantities of cytotoxic T cells, or "killer cells", means that there is a good chance that the disease will take a favorable course and that the risk of metastasis is comparatively low.

5 Feb 2015

Researchers devise new technique to deliver cancer treatment

A team of researchers has devised a new way to target tumors with cancer-fighting drugs, a discovery that may lead to clinical treatments for cancer patients.

5 Feb 2015

Johns Hopkins researchers successfully deliver new nanoparticle gene therapy to treat glioma in rats

Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often deadly form of brain cancer have pointed to the potential of gene therapy, but it's very difficult to effectively deliver toxic or missing genes to cancer cells in the brain.

5 Feb 2015

Research findings demonstrate new approach to transform behavior of tumor cells

Inserting a specific strain of bacteria into the microenvironment of aggressive ovarian cancer transforms the behavior of tumor cells from suppression to immunostimulation, researchers at Norris Cotton Cancer Center and the Geisel School of Medicine at Dartmouth have found.

5 Feb 2015

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

There are two types of thyroid cells and therefore there are two broad types of thyroid cancer. Medullary carcinoma is derived from parafollicular or C cells, whereas follicular cells give rise to several types of thyroid cancers.

4 Feb 2015

Researchers suggest novel concept for developing vaccines against HIV and cancer

A experimental trial has shown successful by inducing serum in mice and has been highly neutralizing towards those ailments.

4 Feb 2015

Study could lead to potential therapeutic targets to treat Ewing Sarcoma

A University of Colorado Cancer Center study published in the journal PLoS One finds alterations in expression of genes PIK3R3 and PTEN, more commonly observed in adult tumors, in the rare, young-adult bone cancer Ewing Sarcoma, potentially offering ways to improve therapy.

4 Feb 2015

New drug gets FDA approval for treatment of women with advanced breast cancer

The U.S. Food and Drug Administration today approved a potentially groundbreaking new drug to treat women with advanced breast cancer, signaling a new treatment strategy to arrest tumor growth and extend the time before the cancer worsens.

4 Feb 2015

Tumor News and Research

New findings could pave way to develop drug therapies for necrosis-related diseases

Salicylates drugs reduce proliferation, viability of cultured vestibular schwannoma cells

New compound may lead to development of potential therapeutics for neuropathic pain

Chinese researchers achieve major breakthrough in nano-carrier drugs for pancreatic cancer

New study provides better understanding of how stem cells give rise to tumors

Chemotherapy or immunosuppressive treatment may reactivate HBV

Prostate cancer patients with detectable post-operative PSA should receive more aggressive treatment

ECOG-ACRIN Cancer Research Group opens clinical trial for women with newly diagnosed DCIS

New NIEHS grants to support independent biomedical research

New study links cell communication pathway to common brain tumors found in children

Crown Bioscience, NRCMM partner to develop new immune-oncology experimental cancer models

Antibodies used in research lab should be made by recombinant DNA technology, say authors

Scientists investigate how T cells in colorectal tumors actively fight cancer

Researchers devise new technique to deliver cancer treatment

Johns Hopkins researchers successfully deliver new nanoparticle gene therapy to treat glioma in rats

Research findings demonstrate new approach to transform behavior of tumor cells

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

Researchers suggest novel concept for developing vaccines against HIV and cancer

Study could lead to potential therapeutic targets to treat Ewing Sarcoma

New drug gets FDA approval for treatment of women with advanced breast cancer

Exploring the G:Box and for high-quality imaging

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How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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