Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects.

16 Dec 2022

Revised guidelines for diabetes care

A recent Diabetes Care journal paper summarized the latest recommendations offered to people with diabetes to improve their health and well-being.

15 Dec 2022

Intermittent fasting diet intervention may help patients to achieve complete diabetes remission

After an intermittent fasting diet intervention, patients achieved complete diabetes remission, defined as an HbA1c (average blood sugar) level of less than 6.5% at least one year after stopping diabetes medication, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

15 Dec 2022

Subcutaneous fat protects against brain inflammation in females

Females' propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopause, scientists report.

14 Dec 2022

What Germany’s coal miners can teach America about medical debt

Almost every day, Dr. Eckart Rolshoven sees the long shadow of coal mining in his clinic near the big brownstone church that dominates this small town in Germany's Saarland.

14 Dec 2022

People with daily step count of 10,700 are 44% less likely to develop type 2 diabetes

Wearable fitness devices offer new insights into the relationship between physical activity and type 2 diabetes, according to a new analysis of the National Institutes of Health's All of Us Research Program data published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

13 Dec 2022

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

In a recent study posted to bioRxiv*, researchers in the United States assessed the impact of metabolic diseases on coronavirus disease 2019 (COVID-19) vaccine immunogenicity in a mouse model.

13 Dec 2022

Study provides new insights for the future development of oral insulin pill

WEHI researchers in Melbourne have answered a 100-year-old question in diabetes research: can a molecule different to insulin have the same effect? The findings provide important insights for the future development of an oral insulin pill.

12 Dec 2022

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

People with diabetes are benefiting from advances in medications and technologies to lower their risk of hypoglycemia, according to a Clinical Practice Guideline issued today by the Endocrine Society.

7 Dec 2022

Paxlovid has been free so far. Next year, sticker shock awaits.

Nearly 6 million Americans have taken Paxlovid for free, courtesy of the federal government. The Pfizer pill has helped prevent many people infected with covid-19 from being hospitalized or dying, and it may even reduce the risk of developing long covid.

7 Dec 2022

Self-service vending machine filled with harm reduction supplies helps prevent overdoses

More than 107,000 Americans died from drug overdose in 2021, highlighting the need for evidence-based interventions.

6 Dec 2022

Gestational diabetes mellitus linked to early particulate matter exposure with high BMI

Researchers assess the impact of high BMI before pregnancy, coupled with exposure to different levels of PM, on the incidence of gestational diabetes.

6 Dec 2022

Parkinson’s drug improves blood pressure, aortic stiffness in adolescents with Type 1 diabetes

Teens with Type 1 diabetes (T1D) who took bromocriptine, a medication used to treat Parkinson's disease and Type 2 diabetes, had lower blood pressure and less stiff arteries after one month of treatment compared to those who did not take the medicine, according to a small study published today in Hypertension, an American Heart Association journal.

6 Dec 2022

Insulin News and Research

Further Reading

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Revised guidelines for diabetes care

Intermittent fasting diet intervention may help patients to achieve complete diabetes remission

Subcutaneous fat protects against brain inflammation in females

What Germany’s coal miners can teach America about medical debt

People with daily step count of 10,700 are 44% less likely to develop type 2 diabetes

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

Study provides new insights for the future development of oral insulin pill

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

Paxlovid has been free so far. Next year, sticker shock awaits.

Self-service vending machine filled with harm reduction supplies helps prevent overdoses

Gestational diabetes mellitus linked to early particulate matter exposure with high BMI

Parkinson’s drug improves blood pressure, aortic stiffness in adolescents with Type 1 diabetes

Novel biosensor enhances performance of home-based continuous glucose monitoring

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Very low-calorie and vegan diets improve glycemic control in type 2 diabetes

SARS-CoV-2 can cause hyperglycemia in cats

Meta-analysis reviews the incidence of new-onset diabetes in COVID-19 survivors

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

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