High Throughput News and Research

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Distribution partnership announced by Nanion Technologies and Axion Biosystems

Nanion Technologies, a leading provider of automated patch clamp platforms, and Axion Biosystems, originator of the first high throughput microelectrode array system, today announce a distribution partnership in Europe and China. Nanion will immediately carry Axion’s MEA-products, supporting a broad range of biomedical applications.

17 Jun 2014

Study examines effect of phthalate exposure in humans’ sperm epigenetics

A new three-year, $440,000 study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst is now underway to investigate whether phthalate levels in expectant fathers have an effect on the couples' reproductive success, via epigenetic modifications of sperm DNA.

12 Jun 2014

High-volume deep well plates available from Porvair Sciences

Precisely manufactured to SLAS/ANSI specifications - Porvair Sciences 24-well deep well plates permit users to simply undertake multiple, high volume (10ml / well) experiments in a single unit maximising both productivity and operational flexibility.

From Chromatrap® - Porvair Sciences Ltd 12 Jun 2014

EU-funded project aims to identify potential new targets for cancer therapy

Targeted therapies have revolutionised the treatment of cancer since they were first introduced. Amongst the first medications approved in Europe, was the breast cancer drug Herceptin, which was approved in 2000. Then, the drug Glivec, was initially introduced to treat a certain form of leukaemia, and approved in 2001. Targeted therapies specifically inhibit molecules within so-called signalling pathways that usually control cell growth, death and differentiation. If they are altered, for example falsely inactivated or activated, the cells may start growing in an uncontrolled manner.

11 Jun 2014

Exercise and diet impact on gut microbial diversity

Scientists at the Science Foundation Ireland-funded Alimentary Pharmabiotic Centre (APC) at University College Cork and Teagasc Food Research Centre, Moorepark, have carried out a study in conjunction with the Irish Rugby Football Union that has revealed that exercise and associated dietary changes influence gut microbial diversity.

10 Jun 2014

Findings add surprising new dimension to understanding of antibody repertoires

As elite soldiers of the body's immune response, B cells serve as a vast standing army ready to recognize and destroy invading antigens, including infections and cancer cells. To do so, each new B cell comes equipped with its own highly specialized weapon, a unique antibody protein that selectively binds to specific parts of the antigen.

10 Jun 2014

Rubicon signs agreements with 7 distributors to expand availability of DNA library preparation products

Rubicon Genomics, Inc., today announced that it signed agreements with seven distributors in Europe to expand the availability of its leading DNA library preparation products, including ThruPLEX®-FD Prep Kit and PicoPLEX™ DNA-seq Kit for use with Illumina® next-generation sequencing (NGS) systems and PicoPLEX™ WGA Kit for use on arrays, and to prepare for new product launches planned for the coming months.

9 Jun 2014

Biosafe launches SepaMax multiprocessing device for high throughput cell processing

In line with its mission of market innovator, Biosafe is proud to announce the launch of the SepaMax multiprocessing device, on the occasion of the International Cord Blood Symposium in San Francisco.

5 Jun 2014

Agena Bioscience expands ultrasensitive somatic mutation detection technology

Agena Bioscience, Inc., which recently acquired the Bioscience business of Sequenom, Inc., today announced expansion of the UltraSEEK™ technology, the first ultrasensitive somatic mutation detection technology for high-throughput and definitive interrogation of rare mutations that occur at less than 1% abundance in matched tissue, circulating plasma, and tumor samples.

31 May 2014

Agena Bioscience acquires Sequenom’s Bioscience business

Agena Bioscience, Inc., a portfolio company of Telegraph Hill Partners (THP), today acquired the Bioscience business of Sequenom, Inc., which sells the MassARRAY® System for mass spectrometry-based detection of nucleic acids in research and clinical laboratories.

31 May 2014

DNA-binding fluorescent dyes evaluate cytotoxicity in real-time during screening

High throughput screening of compounds in live cells is a powerful approach for discovering new drugs, but the potential for cell toxicity must be considered.

31 May 2014

Findings have important implications for improving war wound healing

War wounds that heal successfully frequently contain different microbial species from those that heal poorly, according to a paper published ahead of print in the Journal of Clinical Microbiology.

30 May 2014

RBCC’s BiO Assay wins grant from CASIS for Biological Research in Microgravity

The BiO Assay, a 3D Bioprinting technology being promoted around the world by the joint venture of Rainbow Coral Corp. (OTCBB: RBCC) and Nano3D Biosciences (n3D), has been awarded a research grant from the Center for Advancement of Science in Space (CASIS)—the sole manager of the International Space Station U.S. National Laboratory.

29 May 2014

Study defines specific genetic mechanism that explains some of schizophrenia's heritability

The overall number and nature of mutations—rather than the presence of any single mutation—influences an individual's risk of developing schizophrenia, as well as its severity, according to a discovery by Columbia University Medical Center researchers published in the latest issue of Neuron.

29 May 2014

Twist Bioscience raises $26M in Series B financing, receives $5.1M DARPA contract

Twist Bioscience today announced that it raised $26 million in a Series B financing to commercialize the company's semiconductor-based synthetic gene manufacturing process.

27 May 2014

New 5-layer flask enhances cell culture production

Porvair Sciences has announced a new 5-layer cell culture flask developed to fulfil the need of the growing number of applications that require large numbers of cells.

From Chromatrap® - Porvair Sciences Ltd 22 May 2014

The future of high throughput screening: an interview with Mark Wigglesworth, Director High Throughput Screening, AstraZeneca

Quoting Mike Snowden (VP & Head of Discovery Sciences, AstraZeneca), “it’s where biology meets chemistry”. It’s where for the first time a target protein can be probed for novel molecules that modulate its function, of course we want to do this to prove a hypothesis that these proteins are drug targets with the potential to deliver innovative medicines.

20 May 2014