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Researchers use immune-mimicking biomaterial scaffolds to fast track T cell therapies

Immunologists and oncologists are harnessing the body's immune system to fight cancers and other diseases with adoptive cell transfer techniques. In a normal immune response, a type of white blood cell known as T cells are instructed by another kind of immune cell called an antigen-presenting cell (APC) to expand their numbers and stay alive.

15 Jan 2018

Experts look for ways to standardize treatments for pediatric rheumatic diseases

Pediatric rheumatic diseases are a varied group of rare diseases including juvenile forms of arthritis, lupus, fibromyalgia, and other conditions.

15 Jan 2018

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

Mount Sinai Researchers have just discovered that patients in the Ashkenazi Jewish population with Crohn's disease (a chronic inflammatory of the digestive system) are more likely to carry the LRRK2 gene mutation.

11 Jan 2018

Study finds genetic variations linked to BMI and obesity risk

It's not just diet and physical activity; your genes also determine how easily you lose or gain weight. In a study published in the January issue of Nature Genetics, researchers at the Icahn School of Medicine at Mount Sinai and other institutions of the Genetic Investigation of Anthropometric Traits consortium found 13 genes that carry variations associated with body mass index.

10 Jan 2018

Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

Patients with an aggressive form of leukemia, currently ineligible for any type of targeted therapy, may in fact benefit from some of these new drugs, according to new research by Queen Mary University of London.

9 Jan 2018

New PET tracer can identify, track bacterial lung infection better than current imaging methods

Researchers at the University of Louisville, Kentucky, have demonstrated that a new radiotracer, 2-18F-fluorodeoxysorbitol (18F-FDS), can identify and track bacterial infection in lungs better than current imaging methods and is able to differentiate bacterial infection from inflammation.

8 Jan 2018

New total-body PET scanner could revolutionize patient diagnosis and care

The new total-body PET/CT scanner could revolutionize our understanding and treatment of disease through analysis of better imaging data from the whole body.

3 Jan 2018

UAB study shows missense mutations as key risk factor for severe symptoms of neurofibromatosis type 1

Research led by Ludwine Messiaen, Ph.D., professor of genetics at the University of Alabama at Birmingham, shows that missense mutations in a cluster of just five codons in the NF1 gene are an important risk factor for severe symptoms of the genetic disease neurofibromatosis type 1.

28 Dec 2017

Scientists discover five new regions of the genome that increase asthma risk

An international study led by scientists from Inserm and Paris Diderot Universit, the University of Chicago, the National Heart and Lung Institute and the University of Colorado Anschutz Medical Campus together with researchers of the Trans-National Asthma Genetics Consortium has discovered five new regions of the genome that increase the risk of asthma.

22 Dec 2017

Scientists identify new genes that influence how the body regulates blood pressure

Researchers at the University of Georgia have identified several new genes that influence how the body regulates blood pressure. This may help scientists develop novel blood pressure treatments or even allow them to tailor prevention strategies for individuals based on their genes.

19 Dec 2017

Researchers examine human mutations' impact on therapeutic effect of medicine

Every person has a unique DNA sequence in their genome. Now researchers from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge have tried to quantify what these differences in the genome mean in the context of the genes targeted by drugs.

15 Dec 2017

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced new results from two studies with EndoPredict are being featured at the 2017 San Antonio Breast Cancer Symposium in San Antonio, Texas.

12 Dec 2017

Researchers identify promising solution for improving cystic fibrosis treatments

Researchers at the University of Montreal Hospital Research Centre have identified a promising solution to improving treatments offered to patients with cystic fibrosis.

12 Dec 2017

LSUHealthNO breakthrough may pave way for advances in obesity-related diseases

For the first time, researchers led by Frank Lau, MD, Assistant Professor of Clinical Surgery at LSU Health New Orleans, have successfully kept white fat tissue alive outside of the body for up to eight weeks.

11 Dec 2017

Study indicates decline in use of chemotherapy for early stage breast cancer patients

A study of nearly 3,000 women with early stage breast cancer indicates a recent, significant decline in the use of chemotherapy despite the lack of any change in national treatment recommendations or guidelines, according to researchers at the Stanford University School of Medicine and the University of Michigan.

11 Dec 2017

New 3D-printed artificial models mimic the look and feel of real organs

A team of researchers led by the University of Minnesota has 3D printed lifelike artificial organ models that mimic the exact anatomical structure, mechanical properties, and look and feel of real organs. These patient-specific organ models, which include integrated soft sensors, can be used for practice surgeries to improve surgical outcomes in thousands of patients worldwide.

6 Dec 2017

Clinical study uses genetic testing to match AML patients with new therapies

A clinical trial using genetic testing to match acute myeloid leukemia (AML) patients with new therapies is now open at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center

6 Dec 2017

Harvard scientists discover hundreds of genetic switches that influence height

It's been understood for decades that a host of factors - everything from pre- and post-natal health, nutrition, and genetics - play a role in determining height, but efforts to untangle the complex web of factors that contribute to height have long been stymied.

6 Dec 2017

New study describes unique bioengineered tissue construct for modeling colorectal cancer

A new study describes a unique bioengineered tissue construct, or organoid, into which colorectal cancer cells are embedded, creating a model of the tumor and surrounding extracellular matrix.

6 Dec 2017

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

For prostate cancer patients who have rising levels of PSA (a cancer indicator) even after radical prostatectomy, early treatment makes a difference.

5 Dec 2017

Precision Medicine News and Research

Researchers use immune-mimicking biomaterial scaffolds to fast track T cell therapies

Experts look for ways to standardize treatments for pediatric rheumatic diseases

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

Study finds genetic variations linked to BMI and obesity risk

Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

New PET tracer can identify, track bacterial lung infection better than current imaging methods

New total-body PET scanner could revolutionize patient diagnosis and care

UAB study shows missense mutations as key risk factor for severe symptoms of neurofibromatosis type 1

Scientists discover five new regions of the genome that increase asthma risk

Scientists identify new genes that influence how the body regulates blood pressure

Researchers examine human mutations' impact on therapeutic effect of medicine

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Researchers identify promising solution for improving cystic fibrosis treatments

LSUHealthNO breakthrough may pave way for advances in obesity-related diseases

Study indicates decline in use of chemotherapy for early stage breast cancer patients

New 3D-printed artificial models mimic the look and feel of real organs

Clinical study uses genetic testing to match AML patients with new therapies

Harvard scientists discover hundreds of genetic switches that influence height

New study describes unique bioengineered tissue construct for modeling colorectal cancer

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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