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Researchers identify 'epigenetic fingerprints' of healthy volunteers, patients with common diseases

Until a decade, it was believed that differences between people were due solely to the existence of genetic changes, which are alterations in the sequence of our genes. The discoveries made during these last ten years show that beings with the same genetics like the twins and cloned animals may have different characteristics and disease due to epigenetic changes.

4 Jun 2011

Scientists identify chromosomal mutation responsible for excessive hair growth

Researchers in the Keck School of Medicine of the University of Southern California (USC), together with scientists in Beijing, China, have discovered a chromosomal mutation responsible for a very rare condition in which people grow excess hair all over their bodies.

4 Jun 2011

Researchers discover genomic control system that regulates gut formation in sea-urchin embryos

For all animals, development begins with the embryo. It is here that uniform cells divide and diversify, and blueprints are laid for future structures, like skeletal and digestive systems. Although biologists have known for some time that signaling processes-messages that tell a cell to express certain genes so as to become certain parts of these structures-exist at this stage, there has not been a clear framework explanation of how it all comes together.

4 Jun 2011

Mimicry allows bacteria to evade host's defense responses

Deadly bacteria may be evolving antibiotic resistance by mimicking human proteins, according to a new study by the Translational Genomics Research Institute (TGen).

3 Jun 2011

Study provides insights into evolution and origins of MRSA

A distinctly new type of methicillin resistant Staphylococcus aureus (MRSA) that is not detected by traditional genetic screening methods has been discovered in patients in Irish hospitals according to research to be published in the journal Antimicrobial Agents and Chemotherapy.

3 Jun 2011

PCF funds 14 new Creativity Awards for advanced prostate cancer research

The Prostate Cancer Foundation today announced that it has funded 14 new Creativity Awards for advanced prostate cancer research. These two-year awards are designed to support innovative research ideas that have the potential to achieve breakthroughs for improved prostate cancer diagnosis and treatment.

2 Jun 2011

Study finds novel site within MS4A gene cluster, confirms presence of SNP linked with Alzheimer's

Recently the number of genes known to be associated with Alzheimer's disease has increased from four to eight, including the MS4A gene cluster on chromosome 11.

31 May 2011

Mouse Phylogeny Viewer

Laboratory research has always been limited in terms of what conclusions scientists can safely extrapolate from animal experiments to the human population as a whole. Many promising findings in mice have not held up under further experimentation, in part because laboratory animals, bred from a limited genetic foundation, don't provide a good representation of how genetic diversity manifests in the broader human population.

30 May 2011

Lipidomic profiling can lead to better and earlier prediction of major diseases

Studying the genetic make-up of different varieties of lipids in the blood plasma of an individual can lead to a better and earlier prediction of diseases such as diabetes, atherosclerosis, and heart disease, two researchers will tell the annual conference of the European Society of Human Genetics today.

30 May 2011

BioDiscovery, Affymetrix enter co-marketing agreement for OncoScan FFPE Express Service

Affymetrix, Inc. today announced a co-marketing agreement naming BioDiscovery, Inc. its preferred software provider for Affymetrix OncoScan FFPE Express Service data analysis.

27 May 2011

New genomics research on abnormal brain development

Local researchers are finally on the road to developing targeted treatments for serious, life-long disabilities such as autism and schizophrenia, thanks to new genomics research focusing on abnormal brain development.

27 May 2011

Some African descent men may have higher genetic risk of developing prostate cancer

Some men of African descent may have a higher genetic risk of developing prostate cancer, according to research conducted at the Keck School of Medicine of the University of Southern California.

24 May 2011

Novel hepatitis C-like virus discovered in dogs

In a study to be published online this week in the Proceedings of the National Academy of Sciences, researchers report the discovery of a novel hepatitis C-like virus in dogs. The identification and characterization of this virus gives scientists new insights into how hepatitis C in humans may have evolved and provides scientists renewed hope to develop a model system to study how it causes disease.

24 May 2011

Scientists discover genetic regions that affect severity of cystic fibrosis

A team of international researchers, including Case Western Reserve University School of Medicine, have discovered regions of the genome that affect the severity of the genetic disease cystic fibrosis, the most common lethal genetic disease affecting children in North America.

24 May 2011

Sangamo announces presentations of ZFP Therapeutics data at ASGCT 2011

Sangamo BioSciences, Inc. announced today that data from clinical, preclinical and research-stage programs focused on the development of zinc finger DNA-binding protein Therapeutics were described in twenty presentations given by Sangamo scientists and collaborators at the 14th Annual Meeting of the American Society of Gene and Cell Therapy.

23 May 2011

Roche's new cobas TaqScreen MPX viral discriminatory test, v2.0 now available in Europe

Roche announced today that the cobas TaqScreen MPX Test, version 2.0 for use on the cobas s 201 system is now commercially available in Europe.

23 May 2011

Researchers discover new genes that influence severity of cystic fibrosis

Johns Hopkins Institute for Genetic Medicine researchers working as part of the North American Cystic Fibrosis Consortium have discovered two regions of the genome that affect the severity of cystic fibrosis, a genetic condition that causes scarring throughout the body, affecting most notably the pancreas and lungs.

23 May 2011

Salk researchers successfully edit diseased gene in patient-specific induced pluripotent stem cells

In principle, genetic engineering is simple, but in practice, replacing a faulty gene with a healthy copy is anything but. Using mutated versions of the lamin A gene as an example to demonstrate the versatility of their virus-based approach, researchers at the Salk Institute for Biological Studies successfully edited a diseased gene in patient-specific induced pluripotent stem cells as well as adult stem cells.

21 May 2011

DFG to fund 60 million euros for 18 new Research Training Groups

With the aim of further strengthening early-career research in Germany, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is to establish 18 new Research Training Groups.

21 May 2011

Multiple toxic mechanisms link elevated iron, copper levels in the brain and extensive DNA damage

No one knows the cause of most cases of Alzheimer's, Parkinson's and other neurodegenerative disorders. But researchers have found that certain factors are consistently associated with these debilitating conditions.

21 May 2011

Genome News and Research

Researchers identify 'epigenetic fingerprints' of healthy volunteers, patients with common diseases

Scientists identify chromosomal mutation responsible for excessive hair growth

Researchers discover genomic control system that regulates gut formation in sea-urchin embryos

Mimicry allows bacteria to evade host's defense responses

Study provides insights into evolution and origins of MRSA

PCF funds 14 new Creativity Awards for advanced prostate cancer research

Study finds novel site within MS4A gene cluster, confirms presence of SNP linked with Alzheimer's

Mouse Phylogeny Viewer

Lipidomic profiling can lead to better and earlier prediction of major diseases

BioDiscovery, Affymetrix enter co-marketing agreement for OncoScan FFPE Express Service

New genomics research on abnormal brain development

Some African descent men may have higher genetic risk of developing prostate cancer

Novel hepatitis C-like virus discovered in dogs

Scientists discover genetic regions that affect severity of cystic fibrosis

Sangamo announces presentations of ZFP Therapeutics data at ASGCT 2011

Roche's new cobas TaqScreen MPX viral discriminatory test, v2.0 now available in Europe

Researchers discover new genes that influence severity of cystic fibrosis

Salk researchers successfully edit diseased gene in patient-specific induced pluripotent stem cells

DFG to fund 60 million euros for 18 new Research Training Groups

Multiple toxic mechanisms link elevated iron, copper levels in the brain and extensive DNA damage

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