Precision Medicine News and Research

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CHOP researchers discover key differences among gene fusions in childhood brain tumors

Researchers investigating pediatric low-grade gliomas, the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer.

17 Oct 2017

Study provides early glimpse of gut's microbial landscape

A collaborative effort by a team of researchers from three institutions including the Marine Biological Laboratory in Woods Hole, the Forsyth Institute in Cambridge and Washington University in St. Louis provided an early glimpse of how microbial communities in the gut - known collectively as the gut microbiome - are spatially organized, uncovering a surprising degree of mixing among different bacterial members.

11 Oct 2017

Survey highlights major gap in women’s knowledge about genomic testing in breast cancer

Breast cancer is the most feared type of cancer among women in Germany, according to a recent representative survey commissioned by Agendia, a world leader in personalized medicine and molecular cancer diagnostics.

11 Oct 2017

Forsyth researchers win $5.4 million NIH award to pursue research on oral microbes

A research team led by the Forsyth Institute today received a $5.4 million award from the National Institutes of Health to pursue revolutionary research of microbes living in the mouth and within the human body.

6 Oct 2017

New body-on-a-chip system holds potential for advanced drug screening

Using the same expertise they've employed to build new organs for patients, scientists at Wake Forest Institute for Regenerative Medicine and colleagues have engineered micro hearts, lungs and livers that can potentially be used to test new drugs. By combining the micro-organs in a monitored system, the researchers aim to mimic how the human body responds to medications.

5 Oct 2017

Cancer-fighting cells destroy tumors more effectively after being starved for oxygen

Mountain climbers and endurance athletes are not the only ones to benefit from altitude training - that is, learning to perform well under low-oxygen conditions.

18 Sep 2017

EPFL scientists discover metabolic differences between hepatoblastoma subtypes

Hepatoblastoma is a rare pediatric liver cancer, usually diagnosed in the first three years of life. Histological methods are used to distinguish between the different subtypes of hepatoblastoma.

18 Sep 2017

Myriad Genetics presents positive results of new hereditary cancer test at 36th annual conference of NSGC

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced that two important studies will be featured in podium presentations at the 36th annual conference of the National Society of Genetic Counselors in Columbus, OH.

18 Sep 2017

Prostate Cancer Awareness Month: Myriad Genetics working to educate public about hereditary cancer risk assessment

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, is working to educate the public about hereditary cancer risk assessment and testing during Prostate Cancer Awareness Month this September.

11 Sep 2017

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

Rucaparib maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer by 77%, according to late-breaking results from the ARIEL3 trial reported today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Researchers reveal new approach to precisely identify and treat prostate cancer

Researchers have demonstrated a new, effective way to precisely identify and localize prostate cancer tumors while protecting healthy tissue and reducing side effects.

7 Sep 2017

Myriad Genetics introduces new precision medicine tool to enhance myRisk Hereditary Cancer test

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, announced today that it has launched riskScore, a new clinically validated precision medicine tool to enhance its myRisk Hereditary Cancer test. riskScore quantifies a woman's risk of developing breast cancer by combining genetic markers throughout the genome with her family and clinical history.

7 Sep 2017

Combined PET/CT scanning could identify melanoma patients' response to ICI therapy

Advanced melanoma, a type of skin cancer that has spread to other areas of the body, has a poor prognosis, but immune checkpoint inhibitor therapy can be effective for some patients. Research highlighted in the featured article of the September issue of The Journal of Nuclear Medicine demonstrates that combined positron emission tomography/computed tomography (PET/CT) scanning early in treatment could identify whether the therapy will benefit a particular patient.

6 Sep 2017

Antidepressants used for chronic pain relief come with significant side effects

Chronic pain negatively impacts a person's quality of life. Often, over the counter pain medication, such as ibuprofen or aspirin, are ineffective in alleviating chronic pain. In these instances, a surprising choice is often a drug used to treat an entirely different condition - depression.

5 Sep 2017

Researchers provide approaches to optimize cardiovascular risk reduction for patients with SAMS

Statins are highly effective for preventing heart attacks by reducing low-density lipoprotein or "bad" cholesterol.

29 Aug 2017

New ESC Focused Update provides recommendations on DAPT in patients with coronary artery disease

The first ESC Focused Update on Dual Antiplatelet Therapy in Coronary Artery Disease is published online today in European Heart Journal, and on the ESC website.

26 Aug 2017

DNA sensor systems provide highly sensitive monitoring of cancer-related enzyme activity

The development of DNA sensor systems is of great importance for advances in medical science. Now another piece of the puzzle for the development of personalized medicine has been found with the results of a highly sensitive monitoring of cancer-related topoisomerase II enzymes.

24 Aug 2017

UMass Amherst chemist receives NSF funding to set up new center for autonomous chemistry

University of Massachusetts Amherst chemist Sankaran "Thai" Thayumanavan has received a three-year, $1.8 million grant from the National Science Foundation to create a multi-university Center for Autonomous Chemistry, where he and colleagues, including chemist Vince Rotello, will seek to design artificial self-activating systems, or "automatic control as nature does it," in Thayumanavan's words.

23 Aug 2017

Food allergies: Mechanism underlying cross-reaction between cypress pollen and certain fruits revealed

Working in collaboration with teams from the Czech Republic and Japan, researchers from the Institut Pasteur, Assistance Publique - Hôpitaux de Paris (AP-HP), and Assistance Publique - Hôpitaux de Marseille (AP-HM) have identified, for the first time, the likely origin of the cross-reactivity between cypress pollen, peaches and citrus fruits.

18 Aug 2017

Smartphone interventions may help middle-aged, older adults cope with serious mental illness

The use of new technologies in geriatric psychiatry shows promise for advancing personalized medicine and improving patient care.

16 Aug 2017

Precision Medicine News and Research

CHOP researchers discover key differences among gene fusions in childhood brain tumors

Study provides early glimpse of gut's microbial landscape

Survey highlights major gap in women’s knowledge about genomic testing in breast cancer

Forsyth researchers win $5.4 million NIH award to pursue research on oral microbes

New body-on-a-chip system holds potential for advanced drug screening

Cancer-fighting cells destroy tumors more effectively after being starved for oxygen

EPFL scientists discover metabolic differences between hepatoblastoma subtypes

Myriad Genetics presents positive results of new hereditary cancer test at 36th annual conference of NSGC

Prostate Cancer Awareness Month: Myriad Genetics working to educate public about hereditary cancer risk assessment

Study: Maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer

Researchers reveal new approach to precisely identify and treat prostate cancer

Myriad Genetics introduces new precision medicine tool to enhance myRisk Hereditary Cancer test

Combined PET/CT scanning could identify melanoma patients' response to ICI therapy

Antidepressants used for chronic pain relief come with significant side effects

Researchers provide approaches to optimize cardiovascular risk reduction for patients with SAMS

New ESC Focused Update provides recommendations on DAPT in patients with coronary artery disease

DNA sensor systems provide highly sensitive monitoring of cancer-related enzyme activity

UMass Amherst chemist receives NSF funding to set up new center for autonomous chemistry

Food allergies: Mechanism underlying cross-reaction between cypress pollen and certain fruits revealed

Smartphone interventions may help middle-aged, older adults cope with serious mental illness

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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