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Molecule that blocks bone destruction could provide potential therapeutic target for osteoporosis

UT-Southwestern cancer researchers have identified a promising molecule that blocks bone destruction and, therefore, could provide a potential therapeutic target for osteoporosis and bone metastases of cancer.

26 Jun 2014

Gene partnership may be fueling cancer spread in as much as 20% of cancers

A key cancer-causing gene, responsible for up to 20 percent of cancers, may have a weak spot in its armor, according to new research from the Masonic Cancer Center, University of Minnesota.

25 Jun 2014

Key historical misconceptions hinder research and treatment for brain metastases

"Key historical misconceptions" are hindering progress in research and treatment for patients with cancer metastases to the brain, suggests a special article in the July issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

25 Jun 2014

Patients with Cushing’s syndrome experience significant weight loss while taking oral medication

Sinai Hospital of Baltimore endocrinologist, Henry G. Fein, M.D., today presented new research showing that patients with Cushing's syndrome, a rare disease that can lead to extreme weight gain, type 2 diabetes, high blood pressure and psychological issues, experienced significant, sustained weight loss while taking oral medication daily over a number of years to manage symptoms of the disease.

25 Jun 2014

3D mammography detects more invasive cancers, reduces call-back rates

3D Mammography finds significantly more invasive cancers and reduces unnecessary recalls, according to a large, retrospective study published in June 25 issue of the Journal of the American Medical Association.

25 Jun 2014

Small antioxidant molecules suppress colon cancer associated with colitis

Researchers from Case Western Reserve and Dartmouth universities have shown that a class of small antioxidant molecules carries enormous promise for supressing colon cancer associated with colitis.

25 Jun 2014

Gene in brain promotes kidney cancer, report researchers

A gene known to control brain growth and development is heavily involved in promoting clear cell renal cell carcinoma, the most common form of kidney cancer, researchers from Mayo Clinic in Florida are reporting.

25 Jun 2014

Adeno-associated virus type 2 kills triple-negative breast cancer cells in mice

A virus not known to cause disease kills triple-negative breast cancer cells and killed tumors grown from these cells in mice, according to Penn State College of Medicine researchers. Understanding how the virus kills cancer may lead to new treatments for breast cancer.

24 Jun 2014

New study explores effects of immunotherapy, chemotherapy drugs on non-small cell lung cancer

A new study offered at Houston Methodist Hospital will compare an emerging immunotherapy drug to an existing chemotherapy drug and look at the effects both drugs have on the development of non-small cell lung cancer, a type of cancer which makes up about 85 percent of lung cancer cases.

24 Jun 2014

Mersana and Merck KGaA develop next-generation antibody-drug conjugates

Mersana Therapeutics, Inc., and the biopharmaceutical division of Merck KGaA, Darmstadt, Germany, which operates as EMD Serono in the United States and Canada, announced today an agreement to collaboratively develop next-generation antibody-drug conjugates (ADCs).

24 Jun 2014

Researchers identify two oncogenes that drive the development of medulloblastoma

A new collaborative study carried out by researchers at Sanford-Burnham Medical Research Institute, UC San Diego, the German Cancer Research Center, the University of Heidelberg (Germany), and 33 other research institutions has identified two oncogenes, called GFI1 and GFI1B, that drive the development of medulloblastoma, the most common malignant brain tumor in children.

23 Jun 2014

Physician describes ways to combat post-cancer pain

More and more people are surviving their cancer. Unfortunately, sometimes survival can come with pain. Although many people won't feel any pain after their cancer treatment, some may have chronic, bothersome pain.

23 Jun 2014

Clovis Oncology begins TIGER2 study for treatment of NSCLC patients with EGFR/T790M mutations

Clovis Oncology, Inc. announced today that the TIGER2 study has commenced with the dosing of the first patient at a U.S. study site.

23 Jun 2014

New concept of organs on a chip may help study cancer metastasis

The recent development of the concept of organs on a chip opens the possibility of realistically studying human organs without the use of patients or animal testing.

23 Jun 2014

Celsion acquires all assets of EGEN

Celsion Corporation, an oncology drug development company, today announced the completion of the acquisition by Celsion of substantially all of the assets of EGEN, Inc., a privately-held biopharmaceutical company focused on the development of nucleic acid-based therapeutics for the treatment of cancer and other difficult to treat diseases.

21 Jun 2014

First Edition: June 20, 2014

Today's early morning highlights from the major news organizations, including reports about a new poll of showing a majority of those signing up for marketplace plans had been uninsured before and the Obama administration's decision to extend marriage benefits, including family leave, to same-sex couples.

20 Jun 2014

FAK inhibitors prevent ovarian cancer progression

A team of scientists, led by principal investigator David D. Schlaepfer, PhD, professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine report that small molecule inhibitors to a protein called focal adhesion kinase (FAK) selectively prevent the growth of ovarian cancer cells as tumor spheroids.

20 Jun 2014

Researchers explore how neurons establish spatial polarity and direction in tissues, organs

The question of how neurons and their axons establish spatial polarity and direction in tissues and organs is a fundamental question of any organism or biological system.

20 Jun 2014

NIH receives $10 million grant for research on breast cancer metastasis

The American Cancer Society predicts that 40,000 American women will die from breast cancer this year. Most of those deaths will occur due to cells from the primary tumor that spread to other parts of the body-the process known as metastasis.

20 Jun 2014

Yap1 oncogene drives recurrence and progression of pancreatic cancer

Pancreatic cancer tumors addicted to mutant Kras signaling for their growth and progression have a ready-made substitute to tap if they're ever forced to go cold-turkey on the mutant oncogene, scientists at The University of Texas MD Anderson Cancer Center report in the journal Cell.

20 Jun 2014

Tumor News and Research

Molecule that blocks bone destruction could provide potential therapeutic target for osteoporosis

Gene partnership may be fueling cancer spread in as much as 20% of cancers

Key historical misconceptions hinder research and treatment for brain metastases

Patients with Cushing’s syndrome experience significant weight loss while taking oral medication

3D mammography detects more invasive cancers, reduces call-back rates

Small antioxidant molecules suppress colon cancer associated with colitis

Gene in brain promotes kidney cancer, report researchers

Adeno-associated virus type 2 kills triple-negative breast cancer cells in mice

New study explores effects of immunotherapy, chemotherapy drugs on non-small cell lung cancer

Mersana and Merck KGaA develop next-generation antibody-drug conjugates

Researchers identify two oncogenes that drive the development of medulloblastoma

Physician describes ways to combat post-cancer pain

Clovis Oncology begins TIGER2 study for treatment of NSCLC patients with EGFR/T790M mutations

New concept of organs on a chip may help study cancer metastasis

Celsion acquires all assets of EGEN

First Edition: June 20, 2014

FAK inhibitors prevent ovarian cancer progression

Researchers explore how neurons establish spatial polarity and direction in tissues, organs

NIH receives $10 million grant for research on breast cancer metastasis

Yap1 oncogene drives recurrence and progression of pancreatic cancer

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