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Novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis

A novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis (PVNS), a rare neoplastic joint disorder, according to new phase I data from Memorial Sloan Kettering Cancer Center and other institutions highlighted to media today in advance of the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO), which will take place from May 30 to June 3 in Chicago.

15 May 2014

Phase I study reveals abemaciclib drug shows evidence of single-agent activity in NSCLC patients

Abemaciclib, an oral drug administered twice daily, currently in development by Eli Lilly and Company (NYSE: LLY), has shown evidence of single-agent activity in patients with advanced non-small cell lung cancer in a Phase I study released ahead of the American Society of Clinical Oncology (ASCO) Annual Meeting to be held in Chicago, Ill.

15 May 2014

Scientists find new way to predict response to platinum-based chemotherapy in women with triple-negative breast cancer

Researchers from University Hospitals (UH) Case Medical Center's Seidman Cancer Center will present findings from a study that found the presence of tumor-infiltrating lymphocytes, a type of white blood cell, ahead of treatment may help predict response to platinum-based chemotherapy in women with triple-negative breast cancer.

15 May 2014

SapC-DOPS technology: New way to image glioblastoma multiforme tumors

Just because you can't see something doesn't mean it's not there. Brain tumors are an extremely serious example of this and are not only difficult to treat-both adult and pediatric patients have a five-year survival rate of only 30 percent-but also have even been difficult to image, which could provide important information for deciding next steps in the treatment process.

15 May 2014

Tubal ligation and breastfeeding may lower risk of ovarian cancer in women with BRCA gene mutations

Breastfeeding, tubal ligation - also known as having one's "tubes tied" - and oral contraceptives may lower the risk of ovarian cancer for some women with BRCA gene mutations, according to a comprehensive analysis from a team at the University of Pennsylvania's Basser Research Center for BRCA and the Abramson Cancer Center.

15 May 2014

Nimotuzumab enhances chemo-radiosensitivity by promoting autophagic cell death in ESCC cells

A study which will be published in the May 2014 issue of Experimental Biology and Medicine was aimed at determining whether an EGFR-targeted therapy combined with chemo-radiotherapy can improve local tumor control effectively, compared to cytotoxic agents or irradiation alone.

14 May 2014

USC/NYU researchers develop small molecule that interferes with cancer progression with minimal side effects

A team of researchers from USC and NYU has developed and patented a small molecule that interferes with cancer progression with minimal side effects.

14 May 2014

Scientists identify two new genes that lead to more aggressive forms of prostate cancer

A study by the Columbia University Nova York, in collaboration with the Catalan Institute of Oncology , Belvitge Biomedical Research Institute (ICO-IDIBELL) has identified two new genes that lead to more aggressive forms of prostate cancer.

14 May 2014

Albert Einstein College of Medicine hosts second Stem Cell Symposium focusing on cancer stem cells

Healthy stem cells work to restore or repair the body's tissues, but cancer stem cells have a more nefarious mission: to spawn malignant tumors. Cancer stem cells were discovered a decade ago, but their origins and identity remain largely unknown.

14 May 2014

SGK1 enzyme, asthma and cancer therapies: an interview with Dr. Jonathan D. Powell, Johns Hopkins Kimmel Cancer Center

SGK1 stands for serum/glucocorticoid-regulated kinase 1. SGK1 is a member of the AGC kinase family, which is a huge family of kinases.

13 May 2014

Scientists find new drug that improves effectiveness of radiotherapy in stopping tumor growth

Scientists from The University of Manchester - part of the Manchester Cancer Research Centre - have demonstrated the potential of a drug to improve the effectiveness of radiotherapy in stopping tumour growth.

13 May 2014

Scientists find protein that controls DNA organization during sperm development

Infertility is generally thought of as a woman's problem. In fact, more than 3 million men across America also experience it.

13 May 2014

New study presents novel strategy for treating multiple myeloma

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) provides evidence that genetically modifying immune cells might effectively treat multiple myeloma, a disease that remains incurable and will account for an estimated 24,000 new cases and 11,100 deaths in 2014

13 May 2014

Research team identifies specific genes that may lead to improved survival of glioblastoma

A Henry Ford Hospital research team has identified specific genes that may lead to improved survival of glioblastoma, the most common and deadly form of cancerous brain tumor.

13 May 2014

Researchers use molecular diagnostic methods to detect cancer

The ABC Medical Center, located in Mexico City, implemented various molecular diagnostic methods that can detect the genetic alterations in several types of cancer, so they can select a personalized therapy for each patient and direct it against the mutated genes that cause disease.

13 May 2014

Novel molecule prevents symptoms linked with allergen-induced asthma

A new study carried out by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham), the Max Planck Institute for Colloids and Interfaces (Germany), the Free University of Berlin (Germany), UC San Diego, and Shinshu University (Japan) has identified a novel molecule that prevents T-cells from orchestrating asthma brought on by allergens.

13 May 2014

Tumor News and Research

Novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis

Phase I study reveals abemaciclib drug shows evidence of single-agent activity in NSCLC patients

Scientists find new way to predict response to platinum-based chemotherapy in women with triple-negative breast cancer

SapC-DOPS technology: New way to image glioblastoma multiforme tumors

Tubal ligation and breastfeeding may lower risk of ovarian cancer in women with BRCA gene mutations

Nimotuzumab enhances chemo-radiosensitivity by promoting autophagic cell death in ESCC cells

USC/NYU researchers develop small molecule that interferes with cancer progression with minimal side effects

Scientists identify two new genes that lead to more aggressive forms of prostate cancer

Albert Einstein College of Medicine hosts second Stem Cell Symposium focusing on cancer stem cells

SGK1 enzyme, asthma and cancer therapies: an interview with Dr. Jonathan D. Powell, Johns Hopkins Kimmel Cancer Center

Scientists find new drug that improves effectiveness of radiotherapy in stopping tumor growth

Scientists find protein that controls DNA organization during sperm development

New study presents novel strategy for treating multiple myeloma

Research team identifies specific genes that may lead to improved survival of glioblastoma

Researchers use molecular diagnostic methods to detect cancer

Novel molecule prevents symptoms linked with allergen-induced asthma

2 genes work together to drive most lethal forms of prostate cancer

Foundation Medicine obtains CE mark for FoundationOne

Verastem announces expansion of ongoing COMMAND study in Japan

NSHOA and Caris Life Sciences collaborate to establish personalized cancer care program

Exploring the G:Box and for high-quality imaging

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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