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New methods can advance the development of rapid diagnostics for many infectious diseases

Two companion studies report new artificial intelligence approaches for identification of molecular "fingerprints" for specific infections. The methods, used here to derive a fingerprint for COVID-19, can advance the development of rapid diagnostics for many infectious diseases.

21 Dec 2022

Research reveals how microorganisms found in the gut can worsen C. difficile infections

New research from the University of Virginia School of Medicine and collaborators reveals how microorganisms found in our guts can worsen dangerous C. difficile infections.

21 Dec 2022

Using an AI tool for early identification of Alzheimer's and related dementias in primary care

Rising to meet the formidable challenge of the timely diagnosis of dementia, research scientists from Regenstrief Institute, IUPUI and the medical schools of Indiana University and University of Miami are conducting the Digital Detection of Dementia study, a real-world evaluation of the use of an artificial intelligence (AI) tool they developed for early identification of Alzheimer's disease and related dementias in primary care, the setting where most adults receive healthcare.

21 Dec 2022

Clinical trials demonstrate safety and efficacy of Ebola Zaire vaccines

Two vaccines against the Zaire strain of Ebola virus are immunogenic and safe in both adults and children, according to initial results from two phase II clinical trials published in the New England Journal of Medicine.

21 Dec 2022

IU researchers uncover new ways to prevent serious side effects for breast cancer patients

Researchers at Indiana University School of Medicine are learning more about ways to prevent serious side effects from chemotherapy used to treat breast cancer patients.

20 Dec 2022

Antidepressant use during pregnancy may combine with inflammation to alter offspring neurobiology

Antidepressant use during pregnancy may combine with inflammation to heighten the risk of lifelong neurodevelopmental changes in babies' brains, such as those linked to autism, new research from the University of Virginia School of Medicine suggests.

20 Dec 2022

Nasal antibodies decline nine months after COVID-19 infection, study finds

A new study finds that antibodies produced in the nose decline nine months after COVID-19 infection, while antibodies found in the blood last at least a year.

20 Dec 2022

Bivalent mRNA booster vaccines provide greater short-term protection against symptomatic COVID-19 infection

One of the first real-world data studies comparing the new bivalent mRNA COVID-19 booster vaccines with the original monovalent vaccines reports the bivalent conveyed greater short-term protection against symptomatic COVID-19 infection in adults.

19 Dec 2022

Origins of the serious cancer-like disease LCH discovered

The origins of the serious cancer-like disease LCH have been identified by researchers from Karolinska Institutet in collaboration with Karolinska University Hospital. The findings presented in Science Immunology may lead to new, targeted treatments.

16 Dec 2022

NIH establishes research network to test harm reduction strategies in community settings

To address the overdose crisis in the United States, the National Institutes of Health has established a research network that will test harm reduction strategies in different community settings to inform efforts to help save lives.

16 Dec 2022

Study to determine if a DNA-based blood test can help detect cancer predisposition in NF1 patients

The Children’s Tumor Foundation (CTF) has announced a groundbreaking 3-year study, which it will fund for nearly $2 million, to determine if a DNA-based blood test can offer better understanding and ultimately earlier diagnosis of cancer predisposition in neurofibromatosis type 1 (NF1) patients.

16 Dec 2022

People of all age groups benefit more from COVID-19 vaccines than natural immunity, real-world study finds

In one of the first large, real-world studies comparing the effectiveness of COVID-19 vaccines versus natural immunity in protecting against death, hospitalizations and emergency department (ED) visits for any cause, including COVID, research-scientists from Regenstrief Institute, Indiana University School of Medicine and Vanderbilt University Medical Center report that people of all age groups benefited significantly more from vaccination than natural immunity acquired from a previous COVID infection.

16 Dec 2022

Changing heart cell programming can reverse the lasting damage caused by heart attacks

Back in 1971, the Bee Gees asked, "How can you mend a broken heart?". Now, researchers from Japan reveal that they may just have found a way to repair cardiac damage in patients suffering from chronic heart attack and heart failure.

16 Dec 2022

Sphere Fluidics appoints Richard Hammond as Chief Technical Officer

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, announced today that it has appointed Richard Hammond as Chief Technical Officer.

From Sphere Fluidics 16 Dec 2022

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

HKUMed researchers at AIDS Institute, Department of Microbiology and Department of Surgery, School of Clinical Medicine, and School of Biomedical Sciences discover the role of an isoformic programmed cell death protein 1 (PD-1), namely Δ42PD-1, in suppressing the function of killer T cells, which is a type of immune cells essential for killing cancer cells among hepatocellular carcinoma (HCC) patients.

15 Dec 2022

Randomized trials demonstrate the safety of Ebola vaccine regimens in adults and children

Two randomized, placebo-controlled trials evaluating three Ebola vaccine administration strategies in adults and children found that all the regimens were safe in both age groups, according to results published today in the New England Journal of Medicine.

15 Dec 2022

Common kidney disease could be treated with existing medicines, new study shows

A serious condition that can cause the kidneys to suddenly stop working could be treated with existing medicines, a new study shows.

14 Dec 2022

Individuals with alcohol use disorder less likely to receive treatment for hepatitis C, study shows

A new study supported by the National Institutes of Health shows that individuals with alcohol use disorder (AUD) are less likely to receive antivirals for hepatitis C, despite current guidelines recommending antiviral treatment regardless of alcohol use.

14 Dec 2022

Study finds spike in endocarditis among patients with cocaine or opioid use disorder from 2011 to 2022

The incidence rate of infective endocarditis - a rare but often fatal inflammation of the heart valves - among patients with cocaine use disorder or opioid use disorder increased from 2011 to 2022, with the steepest increase occurring from 2021 to 2022, a new study reports.

13 Dec 2022

NIH's All of Us Research Program begins returning personalized health-related DNA results to participants

The National Institutes of Health's All of Us Research Program has begun returning personalized health-related DNA results to more than 155,000 participants, with reports detailing whether participants have an increased risk for specific health conditions and how their body might process certain medications.

13 Dec 2022

Medical Research News and Research

New methods can advance the development of rapid diagnostics for many infectious diseases

Research reveals how microorganisms found in the gut can worsen C. difficile infections

Using an AI tool for early identification of Alzheimer's and related dementias in primary care

Clinical trials demonstrate safety and efficacy of Ebola Zaire vaccines

IU researchers uncover new ways to prevent serious side effects for breast cancer patients

Antidepressant use during pregnancy may combine with inflammation to alter offspring neurobiology

Nasal antibodies decline nine months after COVID-19 infection, study finds

Bivalent mRNA booster vaccines provide greater short-term protection against symptomatic COVID-19 infection

Origins of the serious cancer-like disease LCH discovered

NIH establishes research network to test harm reduction strategies in community settings

Study to determine if a DNA-based blood test can help detect cancer predisposition in NF1 patients

People of all age groups benefit more from COVID-19 vaccines than natural immunity, real-world study finds

Changing heart cell programming can reverse the lasting damage caused by heart attacks

Sphere Fluidics appoints Richard Hammond as Chief Technical Officer

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

Randomized trials demonstrate the safety of Ebola vaccine regimens in adults and children

Common kidney disease could be treated with existing medicines, new study shows

Individuals with alcohol use disorder less likely to receive treatment for hepatitis C, study shows

Study finds spike in endocarditis among patients with cocaine or opioid use disorder from 2011 to 2022

NIH's All of Us Research Program begins returning personalized health-related DNA results to participants

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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