Adipose News and Research

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Aastrom Biosciences responds to article regarding contaminated stem cell lines

Aastrom Biosciences responded today to the publication in the Sunday online edition of Nature Medicine of findings by California researchers that indicate that certain lines of human embryonic stem cells have been contaminated through the use of mice feeder cells.

25 Jan 2005

Lack of the enzyme acetyl CoA carboxylase 2 turns fat cells into fat burners

Lack of the enzyme, acetyl CoA carboxylase 2 or ACC2, appears to turn the adipose or fat cells of mice into fat burners, explaining in part why the animals can eat more and weigh less than their normal counterparts, said Baylor College of Medicine researchers.

25 Jan 2005

Serono completes enrollment in phase III trial of Serostim

Serono has announced that it has completed enrollment in its second multi-center, phase III trial of Serostim (somatropin [rDNA origin] for injection) in the treatment of HIV-Associated Adipose Redistribution Syndrome (HARS).

24 Jan 2005

International society agrees that the potential of stem cells derived from fat show promising clinical uses

While questions still remain about the nature and function of stem cells found in fat, a group of researchers and clinicians convened today in Pittsburgh at the Second Annual Meeting of the International Fat Applied Technology Society (IFATS) agreed that research should move forward with the ultimate goal of performing human clinical trials to test the cells' therapeutic potential for specific indications.

5 Oct 2004

Interleukin-6 has potential as a therapeutic drug in treating metabolic disorders such as obesity, type 2 diabetes and atherosclerosis

For the most of the past century, researchers have searched for a muscle-contraction-induced factor, which mediates some of the exercise effects in other tissues and organs such as the liver and adipose tissue.

5 Oct 2004

Scientists embark on a five-year study of the effects of soy isoflavones found in dietary supplements on various body tissues

A multidisciplinary team of scientists at the University of Illinois at Urbana-Champaign is embarking on a comprehensive five-year study of the effects of soy isoflavones found in dietary supplements on various body tissues.

29 Sep 2004

Researchers have produced a marathon mouse that can run twice as far as normal mice

By enhancing the function of a single protein, Howard Hughes Medical Institute researchers have produced a “marathon mouse” with altered muscle composition and enough physical endurance to run twice as far as normal mice.

23 Aug 2004

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

By altering the expression of a single -- albeit different – gene, Drs. Roger Davis (UMASS Medical School, USA) and Ying-Hue Lee (Academia Sinica, Taiwan) have succeeded in creating two different strains of transgenic mice that don't gain weight, even when fed fat-laden, high calorie diets.

2 Aug 2004

U-M scientists say Wnt protein prevents obesity by inhibiting fat cell development

Genetically engineered mice, created at the University of Michigan Medical School, are living every dieter's dream.

29 Jun 2004

Asian Indian men more at risk of type 2 diabetes and cardiovascular disease

Asian Indian men are at an increased risk for type 2 diabetes and cardiovascular disease, whether overweight or not, because their bodies metabolize fat like people who are obese, according to researchers at UT Southwestern Medical Center at Dallas.

15 Jun 2004

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get. If a woman is found to have high blood sugar when she's pregnant, but she never had high blood sugar before, she has gestational diabetes.

15 Jun 2004

Conflicting views on embryonic and adult stem cells complicate research in stem cell therapeutics

Though there has been considerable biological and political debate over the use of embryonic stem cells (ESCs) vs. adult stem cells (ASCs) as therapies for tissue engineering and organ transplants, inherent benefits and drawbacks in both techniques compel them to coexist and complement each other.

10 Jun 2004

Cure for age-induced diabetes or cancer may be nearer than we think

Forget the drastic reduction in carbs and calories called for by diet dictators. The day when people can eat their favorite foods, stay thin and live to be 120 without getting age-induced diabetes or cancer may be nearer than we think.

5 Jun 2004

Risk of prostate cancer greater in men over 50 with high levels of testosterone

Men over 50 years of age with high blood levels of testosterone have an increased risk of prostate cancer, according to a study by researchers at Johns Hopkins and the National Institute on Aging. The finding throws some doubt on the safety of testosterone replacement therapy, the investigators say.

11 May 2004

Strategy to treat obesity through molecular liposuction

Researchers at The University of Texas M. D. Anderson Cancer Center have designed a strategy to treat obesity through “molecular liposuction.” The therapy destroys blood vessels supporting fat accumulation — causing the fat to rapidly break down and disappear.

10 May 2004

Sleep apnoea and obesity

Obstructive sleep apnoea syndrome is a common disorder with an estimated prevalence of at least 2 to 4% among middle-aged adults, especially common in obesity.

27 Apr 2004