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Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

It all began with one young patient; a 7-year old boy who was born without a thymus, an important organ of the immune system, and without functional immune cells. The boy also presented with cardiac and skeletal defects, dysmorphic craniofacial features and some signs of autistic behaviors.

23 May 2018

Study shows bacteria behave differently in humans compared to the lab

A recent study has shown that deadly bacteria such as Pseudomonas aeruginosa behave differently in the humans, compared to a laboratory setting.

23 May 2018

Researchers develop injectable bandage to stop fatal blood loss, activate wound healing

While several products are available to quickly seal surface wounds, rapidly stopping fatal internal bleeding has proven more difficult.

22 May 2018

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

How can we detect cancer and viruses with high sensitivity? Physical chemist Laura Fabris-;an associate professor in the Materials Science and Engineering Department at Rutgers, the State University of New Jersey, and principal investigator of the Fabris NanoBio Group-;is addressing this very question.

22 May 2018

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Innate fear is an essential emotion for animals to avoid danger in a severe natural environment. Rodents kept in a laboratory also show instinctive fear behavior against the smell of predators such as foxes, cats or snakes despite having never seen them.

22 May 2018

Staying up all night, sleeping all day can swiftly impact over 100 proteins in the blood

Staying awake all night and sleeping all day for just a few days can disrupt levels and time of day patterns of more than 100 proteins in the blood, including those that influence blood sugar, energy metabolism, and immune function, according to new University of Colorado Boulder research published in the journal PNAS this week.

22 May 2018

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Planning a trip to Mars? You'll want to remember your anti-radiation pills. NASA and private space companies like SpaceX plan to send humans to the red planet within the next 15 years--but among the major challenges facing future crewed space missions is how to protect astronauts from the dangerous cosmic radiation of deep space.

22 May 2018

Researchers uncover clues to early lung transplant failure

Among organ transplant patients, those receiving new lungs face a higher rate of organ failure and death compared with people undergoing heart, kidney and liver transplants. One of the culprits is inflammation that damages the newly transplanted lung.

22 May 2018

New LIVE scoring tool effectively predicts future risk of hospitalization for COPD patients

Researchers have developed a new tool that utilizes basic laboratory tests to effectively identify patients with chronic obstructive pulmonary disease who are at high risk of being hospitalized due to a flare up of the condition.

22 May 2018

Thyroid tumors may be more susceptible to precisely targeted radiation treatment, suggests study

Anaplastic thyroid cancer is almost uniformly fatal, with an average lifespan of about 5 months after diagnosis.

22 May 2018

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Geneticists have been using model organisms ranging from the house mouse to the single-cell bakers' yeast, Saccharomyces cerevisiae, to study basic biological processes that regulate human development and physiology, and that can be compromised in various diseases.

22 May 2018

Scientists identify new drug target to combat chikungunya virus

Scientists have identified a molecule found on human cells and some animal cells that could be a useful target for drugs against chikungunya virus infection and related diseases, according to new research published in the journal Nature.

21 May 2018

Increase in local temperature correlates with higher degree of antibiotic resistance, finds study

Bacteria have long been thought to develop antibiotic resistance largely due to repeated exposure through over-prescribing. But could much bigger environmental pressures be at play?

21 May 2018

Researchers create tool to determine patient's response to immunotherapy drugs

Understanding that not all bladder cancers are the same, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have created a tool that may help them to uncover why only a fraction of patients respond to new immune-based treatments.

21 May 2018

New case report reveals negative clinical impact of using biotin supplement

A new case report in the Journal of the Endocrine Society documents how a patient's use of a common biotin supplement, also known as vitamin B7, caused her to have clinically misleading test results, which prompted numerous consultations and unnecessary radiographic and laboratory testing.

21 May 2018

Study: Prediabetic patients with OSA could lower their resting heart rates by using CPAP

Patients with prediabetes who also have obstructive sleep apnea may improve their resting heart rate, an important measure of cardiovascular health, by using continuous positive airway pressure to treat their OSA, according to a randomized, controlled trial presented at the ATS 2018 International Conference.

21 May 2018

Biomarker blood test does not appear to curb antibiotic overuse, shows new study

Overall antibiotic use was not curbed by giving physicians the results of biomarker tests in patients with suspected lower respiratory tract infections, according to findings from the Procalcitonin Antibiotic Consensus Trial.

21 May 2018

Reducing exposure to hormone interfering chemicals may mitigate obesity risk

Everyday products carry environmental chemicals that may be making us fat by interfering with our hormones, according to research presented in Barcelona at the European Society of Endocrinology annual meeting, ECE 2018.

21 May 2018

Unique nanotechnology method to simplify skin disease diagnosis

In a new SLAS Technology auto-commentary, two authors of an article recently published in Nature Biomedical Engineering ("Abnormal Scar Identification with Spherical Nucleic Acid Technology" – www.nature.com/articles/s41551-018-0218-x) share more insight into their unique method for skin disease diagnosis using NanoFlare nanotechnology.

21 May 2018

New technique allows researchers to control heart cells growing in a dish

Researchers at University of California San Diego School of Medicine and their collaborators have developed a technique that allows them to speed up or slow down human heart cells growing in a dish on command -; simply by shining a light on them and varying its intensity.

21 May 2018

Laboratory News and Research

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

Study shows bacteria behave differently in humans compared to the lab

Researchers develop injectable bandage to stop fatal blood loss, activate wound healing

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Staying up all night, sleeping all day can swiftly impact over 100 proteins in the blood

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Researchers uncover clues to early lung transplant failure

New LIVE scoring tool effectively predicts future risk of hospitalization for COPD patients

Thyroid tumors may be more susceptible to precisely targeted radiation treatment, suggests study

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Scientists identify new drug target to combat chikungunya virus

Increase in local temperature correlates with higher degree of antibiotic resistance, finds study

Researchers create tool to determine patient's response to immunotherapy drugs

New case report reveals negative clinical impact of using biotin supplement

Study: Prediabetic patients with OSA could lower their resting heart rates by using CPAP

Biomarker blood test does not appear to curb antibiotic overuse, shows new study

Reducing exposure to hormone interfering chemicals may mitigate obesity risk

Unique nanotechnology method to simplify skin disease diagnosis

New technique allows researchers to control heart cells growing in a dish

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