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Researchers identify new mechanism to disrupt HIV latency

HIV, the virus that causes AIDS, has a secret life. Though anti-retroviral therapy can reduce its numbers, the virus can hide and avoid both treatments and the body's immune response.

8 Mar 2018

Of ‘miracles’ and money: Why hemophilia drugs are so expensive

When Landon Morris was diagnosed with hemophilia shortly after birth, his mother, Jessica Morris, was devastated. "It was like having your dreams — all the dreams you imagined for your child — just kind of disappear," she recalled.

8 Mar 2018

Technological advances in biosensors could reduce spread of HIV infection

1.8 million people acquire HIV each year, with the World Health Organisation estimating that 1 in 5 people living with HIV do not realize they are infected. Therefore, strategies for faster and earlier diagnosis are as important as ever to limit the spread of HIV.

From IDTechEx Ltd 7 Mar 2018

FDA approves new antiretroviral medication for patients with multidrug-resistant HIV

Today, the U.S. Food and Drug Administration approved Trogarzo (ibalizumab-uiyk), a new type of antiretroviral medication for adult patients living with HIV who have tried multiple HIV medications in the past (heavily treatment-experienced) and whose HIV infections cannot be successfully treated with other currently available therapies (multidrug resistant HIV, or MDR HIV).

6 Mar 2018

One-month antibiotic regimen to prevent TB as safe, effective as nine-month therapy for HIV patients

A one-month antibiotic regimen to prevent active tuberculosis (TB) disease was at least as safe and effective as the standard nine-month therapy for people living with HIV, according to the results of a large international clinical trial.

6 Mar 2018

Johns Hopkins doctors successfully transplant hepatitis C-infected kidneys into virus-free patients

In a small study, doctors at Johns Hopkins have successfully transplanted 10 hepatitis C-infected kidneys into patients without hepatitis C and prevented the patients from becoming infected by hepatitis C. The success of these transplants could mean more organs being available for the nearly 100,000 people in the U.S. currently waiting for a kidney transplant.

6 Mar 2018

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), led by Dr. Alicia G. Arroyo, have identified a function of a protease that could be targeted for the treatment of some infections and even tumor metastasis.

2 Mar 2018

Scientists identify single genetic change in Salmonella that plays key role in bloodstream infections

Scientists have identified a single genetic change in Salmonella that is playing a key role in the devastating epidemic of bloodstream infections currently killing around 400,000 people each year in sub-Saharan Africa.

1 Mar 2018

Home-based semen analysis kit could provide rapid, cost-effective way to test male fertility

It is estimated that of the 70 million cases of infertility worldwide, almost half are caused by factors relating to the male partner. A number of semen parameters – motility, morphology, velocity, volume, concentration, and count – affect male fertility.

28 Feb 2018

Researchers developing rapid saliva test to detect Zika virus

Researchers at New York University College of Dentistry, in collaboration with Rheonix, Inc., are developing a novel test for Zika virus that uses saliva to identify diagnostic markers of the virus in a fraction of the time of current commercial tests.

24 Feb 2018

Modifications in HIV test enable rapid detection of Zika virus, study states

A new comprehensive study details a novel test for Zika virus, which utilizes saliva for rapid identification of the diagnostic markers of the virus.

23 Feb 2018

MSD and Ferring Pharmaceuticals Complete Largest Ever Clinical Trial in Postpartum Haemorrhage

Today, Ferring Pharmaceuticals and MSD, via its MSD for Mothers initiative, announced the completion of CHAMPION (Carbetocin Haemorrhage Prevention), a global clinical trial conducted by the Human Reproduction Program (HRP) at the World Health Organization (WHO).

22 Feb 2018

Researchers create algorithm to reduce spread of infectious diseases

Public outreach campaigns can prevent the spread of devastating yet treatable diseases such as tuberculosis (TB), malaria and gonorrhea. But ensuring these campaigns effectively reach undiagnosed patients, who may unknowingly spread the disease to others, is a major challenge for cash-strapped public health agencies.

21 Feb 2018

Researchers to study whether menstrual cups can help prevent vaginal infections

Researchers at the University of Illinois at Chicago will conduct a study to determine how the use of menstrual cups helps prevent vaginal infections and sexually transmitted infections.

20 Feb 2018

MS patients who feel stigmatized more likely to suffer from depression

People with Multiple Sclerosis -- MS -- who feel stigmatized are more likely to suffer from depression, according to researchers, who add that having a support system of friends and family and a sense of autonomy may help reduce the harmful effects of stigma.

20 Feb 2018

Resolving Interfacial Protein Dynamics by STReM

STReM stands for Super Time-Resolved Microscopy, and as STORM, PALM, and other methods are designed to improve spatial resolution of optical microscopy, we desire to improve the time resolution. STReM makes use of point spread function engineering to encode fast events into each camera frame.

From Pittcon 16 Feb 2018

UNC study finds HIV risk patterns among people who inject drugs in Vietnam

People who inject drugs (PWID) in Vietnam are disproportionately affected by HIV. While HIV prevalence among the general population aged 15-49 is 0.4 percent, the prevalence of HIV among people who inject drugs is a staggering 11 percent, according to UNAIDS.

6 Feb 2018

Researchers report technical advances in production of HIV vaccines

Research on HIV over the past decade has led to many promising ideas for vaccines to prevent infection by the AIDS virus, but very few candidate vaccines have been tested in clinical trials.

6 Feb 2018

Depression treatment helps non-cancer pain patients to stop taking opioids

Opioid cessation in non-cancer pain may be more successful when depression is treated to remission, a Saint Louis University study shows.

5 Feb 2018

Research uncovers how viruses outsmart the immune system

How do viruses that cause chronic infections, such as HIV or hepatitis c virus, manage to outsmart their hosts' immune systems? The answer to that question has long eluded scientists, but new research from McGill University has uncovered a molecular mechanism that may be a key piece of the puzzle. The discovery could provide new targets for treating a wide range of diseases.

5 Feb 2018