Enzyme News and Research

RSS

Scientists find molecular mechanisms linking sugar production and longevity

Johns Hopkins researchers have discovered a new energy-making biochemical twist in determining the lifespan of yeast cells, one so valuable to longevity that it is likely to also functions in humans.

23 Mar 2009

Alcohol flush signals increased cancer risk among east Asians

Many people of East Asian descent possess an enzyme deficiency that causes their skin to redden, or flush, when they drink alcohol.

23 Mar 2009

Garden peas may help fight high blood pressure, kidney disease

Researchers in Canada are reporting that proteins found in a common garden pea show promise as a natural food additive or new dietary supplement for fighting high blood pressure and chronic kidney disease (CKD).

22 Mar 2009

Gulf War veterans display abnormal brain response to specific chemicals

A new study by UT Southwestern Medical Center researchers is the first to pinpoint damage inside the brains of veterans suffering from Gulf War syndrome - a finding that links the illness to chemical exposures and may lead to diagnostic tests and treatments.

22 Mar 2009

New therapeutic approaches to castrate resistant prostate cancer

Today Dr. Martin Gleave of the Vancouver Prostate Centre in Canada gave a lecture about new approaches to treat castrate-resistant prostate cancer (CRCP) during the 24 th Annual Congress of the European Association of Urology in Stockholm, Sweden.

22 Mar 2009

Tobacco for drug synthesis

Tobacco isn't famous for its health benefits. But now scientists have succeeded in using genetically modified tobacco plants to produce medicines for several autoimmune and inflammatory diseases, including diabetes. The research is published in the open access journal BMC Biotechnology.

20 Mar 2009

Researchers investigate new way to block reproduction of the hepatitis C virus

Massachusetts General Hospital (MGH) researchers are investigating a new way to block reproduction of the hepatitis C virus (HCV) - targeting not the virus itself but the human genes the virus exploits in its life cycle.

20 Mar 2009

Scientists closer to understanding how to control high blood sugar

Scientists are closer to understanding which proteins help control blood sugar, or glucose, during and after exercise.

20 Mar 2009

Naltrexone can reduce relapse rates among alcohol-dependence patients

Naltrexone, an opioid antagonist approved in 1994 by the U.S. Food and Drug Administration for alcohol-dependence (AD) treatment, can reduce relapse rates among AD patients.

20 Mar 2009

Anti-seizure drugs may increase risk of cardiovascular problems

An important clinical repercussion in the treatment of epilepsy has been discovered by a research team led by Scott Mintzer, M.D., assistant professor in the Department of Neurology and the Jefferson Comprehensive Epilepsy Center at Jefferson Medical College of Thomas Jefferson University.

20 Mar 2009

Blocked enzyme reverses schizophrenia-like symptoms

Researchers at MIT's Picower Institute for Learning and Memory have found that inhibiting a key brain enzyme in mice reversed schizophrenia-like symptoms.

20 Mar 2009

Gleevec reduces risk of cancer returning in patients with life-threatening gastrointestinal stromal tumors

Data published online and in an upcoming print issue of The Lancet show that Gleevec (imatinib mesylate) tablets, when taken after surgery, substantially reduces the rate of recurrence of Kit-positive gastrointestinal stromal tumors (GIST) compared with placebo.

20 Mar 2009

Epigenetic mark guides stem cells toward their destiny

Not all stem cells are completely blank slates. Some, known as adult stem cells, have already partially embraced their fates, and are capable of becoming only cells of a particular type of tissue.

20 Mar 2009

Compound is key coordinator of clock and metabolism

Our circadian clock, or biological timing system, governs our daily cycles of feeding, activity and sleep.

20 Mar 2009

Paradigm shift in the regulation of immune response

Over the past decade various pieces of the puzzle how signal transmission controls immunity have been coming together.

20 Mar 2009

Epigenetic mark guides stem cells toward their destiny

Not all stem cells are completely blank slates. Some, known as adult stem cells, have already partially embraced their fates and are capable of becoming only cells of a particular type of tissue. So how do these tissue-specific stem cells restrict their fate?

19 Mar 2009

Drug pactimibe does not appear to reduce progression of atherosclerosis

Compared to placebo, the drug pactimibe did not effect certain measures of atherosclerosis for patients with familial hypercholesterolemia (high cholesterol levels), but these patients did have an increased incidence of cardiovascular events such as heart attack and stroke, according to a study in the March 18 issue of JAMA.

17 Mar 2009

Alzheimer's mechanism suggests combination therapy needed

Researchers at the University of Illinois at Chicago College of Medicine have discovered a mode of action for mysterious but diagnostic protein snarls found in the brains of Alzheimer's patients that suggests a one-two punch of therapy may be needed to combat the neurodegenerative disease.

17 Mar 2009

FDA looks at nanotechnology for the detection of anthrax

The U.S. Food and Drug Administration has completed a "proof-of-concept" study of a test that quickly and accurately detects the presence of even the smallest amount of the deadly anthrax toxin.

17 Mar 2009

Discovery of new mechanism for the processing of endocannabinoids

New research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, has identified a new mechanism for the processing of endocannabinoids, natural brain compounds similar to THC, the active ingredient in marijuana.

17 Mar 2009