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ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts.

30 Apr 2024

New SARS-CoV-2 KP.2 variant defies vaccines with higher spread, study warns

Study on the bioRxiv server reports that the SARS-CoV-2 KP.2 variant, despite lower infectivity, shows significant immune resistance and higher transmissibility compared to other variants, potentially impacting global public health and vaccine efficacy.

29 Apr 2024

Enzyme discovery paves the way for developing universal donor blood

Researchers at DTU and Lund University have discovered enzymes that remove hindrances that stood in the way of developing universal donor blood.

29 Apr 2024

Sino Biological finalizes the acquisition of SignalChem Biotech, strengthening global presence and expanding product portfolio

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From Sino Biological Inc. 29 Apr 2024

Ohio State study reveals bacterial defense mechanism against phages

One of the many secrets to bacteria's success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves.

26 Apr 2024

Revvity unveils a new era of automated tuberculosis testing

Revvity, Inc. (NYSE: RVTY) today announced the launch of the Auto-Pure 2400 liquid handler from Allsheng for use with the T-SPOT.TB test. The Auto-Pure 2400 platform is easy to use and designed to provide efficient workflows in the lab. When the accuracy of the T-SPOT.TB test is combined with the efficiency of the Auto-Pure 2400 system, labs, clinicians and ultimately patients, benefit from the resultant powerful solution.

From Revvity 26 Apr 2024

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Study investigated whether SARS-CoV-2 lingers in tissues after COVID-19 recovery and if it's linked to long COVID symptoms. They found viral RNA in various organs, and its presence correlated with long COVID symptoms.

25 Apr 2024

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.

25 Apr 2024

MIT study reveals circadian impact on drug metabolism in engineered livers

Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.

25 Apr 2024

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine announces that it has received approval from the U.S. Food and Drug Administration for its Investigational New Drug application for ISM3412, a small molecule inhibitor of MAT2A for the potential treatment of MTAP deleted cancers designed with Insilico's generative AI platform.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Paclitaxel treatment found to directly promote HBV replication and transcription

Hepatitis B virus (HBV) reactivation is commonly observed in individuals with chronic HBV infection undergoing antineoplastic drug therapy.

24 Apr 2024

New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

A tARC-seq approach to precisely determine SARS-CoV-2 mutation frequency.

24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

23 Apr 2024

Immune dysfunction mechanism discovered in stroke and heart attack patients

Every year, between 250,000 and 300,000 people in Germany suffer from a stroke or heart attack.

23 Apr 2024

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Tafenoquine, a prodrug that could fulfill the criteria for a mass eradication campaign.

23 Apr 2024

Study discovers hidden mechanism behind rapid COVID variants

The SARS-CoV-2 virus that causes COVID has the unsettling ability of often generating variants of itself. Other viruses also mutate, but as SARS-CoV-2 quickly spread throughout the entire human population during the pandemic, killing millions, the virus' dynamic evolution posed a serious problem: it repeatedly challenged our bodies' immune response fighting the virus and hindered the process of getting updated vaccines ready.

23 Apr 2024

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

A review in Current Research in Food Science explores how bioactive compounds in coffee, tea, and cocoa combat obesity by inhibiting white adipogenesis and promoting brown adipogenesis and lipolysis.

22 Apr 2024

Enzyme News and Research

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

New SARS-CoV-2 KP.2 variant defies vaccines with higher spread, study warns

Enzyme discovery paves the way for developing universal donor blood

Sino Biological finalizes the acquisition of SignalChem Biotech, strengthening global presence and expanding product portfolio

Ohio State study reveals bacterial defense mechanism against phages

Revvity unveils a new era of automated tuberculosis testing

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

MIT study reveals circadian impact on drug metabolism in engineered livers

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

New system personalizes chemotherapy doses for cancer patients

Paclitaxel treatment found to directly promote HBV replication and transcription

New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

Immune dysfunction mechanism discovered in stroke and heart attack patients

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Study discovers hidden mechanism behind rapid COVID variants

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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