Enzyme News and Research

RSS

New inhibitors could be new class of cancer drugs

A team of Vanderbilt University Medical Center investigators has developed a group of chemical compounds that could represent a new class of drugs for treating cancer.

3 Feb 2009

New chemical keeps stem cells young

Scientists at the Universities of Bath and Leeds have discovered a chemical that stops stem cells from turning into other cell types, allowing researchers to use these cells to develop new medical treatments more easily.

3 Feb 2009

Heart drug improve learning and memory in middle-aged rats

A team of Arizona psychologists, geneticists and neuroscientists has reported that a safe and effective drug used to treat vascular problems in the brain has improved spatial learning and working memory in middle-aged rats.

2 Feb 2009

Fasudil could reduce risk of Alzheimer's

A drug used to improve blood flow to the brain also could help improve learning and memory and reduce the risk of Alzheimer's disease, according to a new study released today by investigators at the Translational Genomics Research Institute (TGen) and Arizona State University.

2 Feb 2009

Fibroblasts invade at a snail's pace

A transcription factor known to drive the formation of fibroblasts during development also promotes their ability to invade and remodel surrounding tissues, report Rowe et al. in the February 9, 2009 issue of the Journal of Cell Biology.

2 Feb 2009

Discovery fleshes out metabolism of key environmental and energy bacteria

An international collaboration of researchers has discovered a new enzyme in a species of bacteria with potential environmental cleanup and energy roles.

2 Feb 2009

Inflammation in colon may get doused before fueling cancer development

A tiny molecule found in most plant-based foods douses the flames before damaging lesions can form in the colon, according to a study by Texas AgriLife Research scientist Dr. Nancy Turner.

2 Feb 2009

New compound shows potential as tuberculosis drug

Rajesh Gokhale has created a compound in his lab in India that stops tuberculosis in its tracks.

2 Feb 2009

Rare amino acid helps establish how proteins evolve

Three billion years ago, a "new" amino acid was added to the alphabet of 20 that commonly make up proteins in organisms today.

29 Jan 2009

Component of DNA stimulates and suppresses the immune response

A component of DNA that can both stimulate and suppress the immune system, depending on the dosage, may hold hope for treating cancer and infection, Medical College of Georgia researchers say.

29 Jan 2009

Statins may treat cerebral cavernous malformation

In a finding that could save thousands of lives a year, University of Utah School of Medicine researchers have shown that a blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis or other problems is treatable with the same statin drugs that millions of people take to control high cholesterol.

27 Jan 2009

The drug treatment of heart failure is influenced by the gender of the patient and of the physician

While the treatment of heart failure has improved over the past two decades, a new study reported in the European Journal of Heart Failure finds that "the use of evidence-based treatments appears to be imbalanced according to the gender of the patient".

23 Jan 2009

Researchers create precise biosensor for detecting blood glucose

Researchers have created a precise biosensor for detecting blood glucose and potentially many other biological molecules by using hollow structures called single-wall carbon nanotubes anchored to gold-coated "nanocubes."

23 Jan 2009

Inflammation worsens danger due to atherosclerosis

Current research suggests that inflammation increases the risk of plaque rupture in atherosclerosis.

23 Jan 2009

First '3D movie' of tumour protein gives new drug hope

First '3D movie' of tumour protein gives new drug hope CANCER RESEARCH UK scientists have created the first complete model of a molecule which captains a key cell signalling network to prevent cancer - and exposed the secret of how a highly selective drug can intervene to control its activity, according to a study published in PLoS Biology.

23 Jan 2009

The drug treatment of heart failure is influenced by the gender of the patient and of the physician

21 Jan 2009

Migraines linked to mental disorders

Migraine headaches can precede the onset of mental disorders, according to a growing body of knowledge that includes a new study in the January-February 2009 issue of General Hospital Psychiatry.

21 Jan 2009

Potential new target in the war on HIV/AIDS

The study revealed that a variant of a protein involved in HIV pathogenesis can suppress production of an HIV protein, known as Nef. Nef is required for the human immunodeficiency virus to develop into AIDS through a series of complex events involving viral elements and cellular proteins. Nef has never been a target for drug treatment in HIV patients.

21 Jan 2009

Researchers identify biochemical switch required for nerve cells to respond to DNA damage

The finding, scheduled for advance online publication in Nature Cell Biology, illuminates a connection between proteins involved in neurodegenerative disease and in cells' response to DNA damage.

19 Jan 2009

Less severe first heart attacks linked to decline in coronary heart disease deaths

The severity of first heart attacks has dropped significantly in the United States - propelling a decline in coronary heart disease deaths, researchers reported in Circulation: Journal of the American Heart Association.

19 Jan 2009