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Scientists identify genetic clues to chronic kidney disease

Using international genomic studies backed by proof-of-concept cell experiments, researchers have identified two genes that contribute to the chronic kidney disease glomerulonephritis.

16 Mar 2017

Mount Sinai scientists publish results from pioneering iPhone study of asthma patients

Scientists from the Icahn School of Medicine at Mount Sinai today published results from a pioneering study of asthma patients in the U.S. conducted entirely via iPhone using the Apple ResearchKit framework and the Asthma Health app developed at Mount Sinai with collaborating organizations.

13 Mar 2017

New computer models could help researchers to better predict side-effects of drugs

New computer models from North Carolina State University show how a variant of a common protein involved in human immune response binds to the antiviral drug abacavir, causing a severe life-threatening reaction known as the abacavir hypersensitivity syndrome

8 Mar 2017

New technique can effectively identify cancer-causing substances in urine or blood

A team of researchers, led by Professor Yoon-Kyoung Cho of Life Science at UNIST has recently developed a new technique that effectively identifies cancer-causing substances in the urine or blood.

7 Mar 2017

New PET radiotracer can quickly, non-invasively detect life-threatening atherosclerotic plaques

In the featured article of the March 2017 issue of "The Journal of Nuclear Medicine," researchers demonstrate that a new positron emission tomography radiotracer, gallium-68 (Ga-68)-pentixafor, can quickly and non-invasively identify life-threatening atherosclerotic plaques.

1 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients

Donepezil, a medication that is approved to treat people with Alzheimer's disease, should not be prescribed for people with mild cognitive impairment without a genetic test.

24 Feb 2017

Researchers reveal biological pathways involved in diabetic kidney disease

Diabetes is a leading cause of kidney disease, a serious, often fatal complication that is difficult to diagnose in early, potentially treatable stages.

24 Feb 2017

Scientists create organ-on-a-chip that can mimic heart's biomechanical properties

The human heart beats more than 2.5 billion times in an average lifetime. Now scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart's amazing biomechanical properties.

23 Feb 2017

Study shows potential of 3D tracking system in improving accuracy of robot-assisted surgery

The cutting-edge biocompatible near-infrared 3D tracking system used to guide the suturing in the first smart tissue autonomous robot surgery has the potential to improve manual and robot-assisted surgery and interventions through unobstructed 3D visibility and enhanced accuracy, according to a study published in the March 2017 issue of IEEE Transactions on Biomedical Engineering.

17 Feb 2017

Experts outline new methodologies that may lead to individualized patient care

In the current issue of Psychotherapy and Psychosomatic Dr. Ralph Horwitz and colleagues outline new methodologies, in addition to the well-known randomized controlled trials, to gather information that may lead to individualized patient care.

16 Feb 2017

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

The Helmholtz Zentrum München has published results of the largest genome-wide association study on proteomics to date.

16 Feb 2017

Scientists aim to create data mining tools to identify personalized treatment options for cancer

In the laboratories of Institute of Molecular Medicine Finland, drug testing is done ex vivo. That is, various leukemia drugs are tested with patient samples instead of the patients themselves. This enables the researchers to test different drug combinations efficiently and without burdening the patient.

13 Feb 2017

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Researchers have identified a gatekeeper protein that prevents pancreatic cancer cells from transitioning into a particularly aggressive cell type and also found therapies capable of thwarting those cells when the gatekeeper is depleted.

9 Feb 2017

Horror movie scenes help researchers identify key neural pathway for processing fear

Researchers at the University of California, Irvine have identified a key neural pathway in humans that explains how the brain processes feelings of fear and anxiety, a finding that could help scientists unlock new ways to treat mental health disorders.

8 Feb 2017

Studies open new windows into understanding untreatable group of common genetic disorders

Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that are characterized by distinct facial features, developmental delays, cognitive impairment and heart problems.

7 Feb 2017

New PET radiotracer effectively detects early and advanced stages of prostate cancer

In the featured article from the February 2017 issue of the Journal of Nuclear Medicine, researchers document the first-in-human application of a new imaging agent to help find prostate cancer in both early and advanced stages and plan treatment.

1 Feb 2017

European researchers highlight potential of xenografts in cancer research and treatment

European research lays the foundation for the development of new and ambitious research projects with xenografts derived from patients, preclinical models with great potential to advance research and treatment in cancer.