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Smoking influences survival of nasopharyngeal carcinoma patients

Survivors of nasopharyngeal carcinoma who are former or current smokers are more likely to have their disease progress, relapse, or spread, and are more likely to die of their disease, compared with survivors of nasopharyngeal carcinoma who have never smoked, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

21 Nov 2013

Findings show how cancer and aging are tightly interconnected

Researchers from the Geisel School of Medicine at Dartmouth have found that epigenetic changes to DNA are associated with aging in disease-free breast tissues and are further altered in breast tumors. Epigenetic changes describe heritable alterations caused by mechanisms other than by changes in DNA sequence. The discovery, published in the February 2014 issue of Epigenetics, illustrates how cancer and aging are tightly interconnected processes by identifying epigenetic alterations present in the normal aging breast that may increase disease risk in cancer-free individuals.

21 Nov 2013

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

What we are trying to do is take a cancer model like the PDX model (patient-derived tumor xenograft), which is a human-derived cancer growing in an in vivo model and apply radiation to that model.

From Xstrahl 20 Nov 2013

DNA-damaging drug and MK2 inhibitor combination could be effective against cancer

About half of all cancer patients have a mutation in a gene called p53, which allows tumors to survive and continue growing even after chemotherapy severely damages their DNA.

20 Nov 2013

Tasquinimod drug effective for men with metastatic castration-resistant prostate cancer

An investigational prostate cancer treatment slows the disease's progression and may increase survival, especially among men whose cancer has spread to the bones, according an analysis led by the Duke Cancer Institute.

20 Nov 2013

First patients enrolled in EF-21 Study of NovoTTF Therapy for brain metastases from NSCLC cancer

Novocure announced today that the first patients have enrolled in the EF-21 Study, a prospective randomized clinical study of NovoTTF Therapy for patients with brain metastases from non-small cell lung carcinoma cancer. NovoTTF Therapy is an anti-mitotic treatment delivered continuously throughout the day by the NovoTTF-100A System.

20 Nov 2013

Serametrix launches new MDSC-based blood test for cancer patients

Serametrix Corporation has announced the launch of an important new blood test for cancer patients. The test measures a patient's level of circulating Myeloid Derived Suppressor Cells (MDSCs) that are known to decrease anti-tumor immunity and are associated with poor survival rates in cancer patients.

20 Nov 2013

Loyola University initiates clinical trial of vaccine that trains immune system to fight melanoma

Loyola University Medical Center is enrolling melanoma patients in the first clinical trial in the Midwest of an experimental vaccine that trains a patient's immune system to fight the deadly cancer.

20 Nov 2013

UC San Diego study suggests racial inequality leads to higher mortality in cancer patients

Researchers at the University of California, San Diego School of Medicine say metastatic colorectal cancer patients of African-American descent are less likely to be seen by cancer specialists or receive cancer treatments. This difference in treatment explains a large part of the 15 percent higher mortality experienced by African-American patients than non-Hispanic white patients.

20 Nov 2013

Boston Scientific's Direxion Torqueable Microcatheter receives FDA clearance and CE Mark approval

Further bolstering its market-leading portfolio of peripheral embolization technologies, Boston Scientific Corporation has received U.S. Food and Drug Administration clearance and CE Mark approval for its Direxion Torqueable Microcatheter.

20 Nov 2013

Patients treated with high-risk endoscopic procedure less likely to be admitted in hospital

Patients who seek treatment from physicians who more frequently perform a high-risk endoscopic procedure are less likely to be admitted to the hospital or require a repeat procedure. Unfortunately, 90 percent of physicians performing these procedures do very few of them.

19 Nov 2013

Study confirms therapeutic potential of inhibiting Aurora-A in cancer treatment

Aurora-A is a protein involved in the cell division process that is highly expressed or synthesised in a large number of human cancers, especially in those associated with a bad prognosis. Several pharmaceutical companies have recently developed these protein inhibitors, although the therapeutic and physiological effects that blocking Aurora-A might have on adult tissues are still unknown.

19 Nov 2013

Findings may help scientists better understand prognosis of advanced prostate cancer

Many patients diagnosed with prostate cancer have indolent, slow-growing forms of the disease that are not life-threatening. However, more than 30,000 American men will die from aggressive prostate cancer this year alone. This sharp contrast between low-risk and aggressive disease presents a challenge for many researchers and physicians as they diagnose patients and also determine the prognosis of the men with the most aggressive forms of prostate cancer.

19 Nov 2013

Extract from bitter melon may have therapeutic qualities to treat head and neck cancer

Extract taken from an Asian vegetable may have therapeutic qualities to treat head and neck cancer, a Saint Louis University researcher has found.

19 Nov 2013

Obese women face increased risk of developing aggressive sub-type of breast cancer

Women who are obese face an increased risk of developing an aggressive sub-type of breast cancer known as 'basal-like', according to research conducted at the University of North Carolina.

19 Nov 2013

Medical–surgical integration ‘boosts neoadjuvant chemotherapy use for bladder cancer’

Research from the USA indicates that a multidisciplinary approach and coordination between medical and surgical oncology services can help optimize the use of neoadjuvant chemotherapy for bladder cancer.

18 Nov 2013

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Findings by scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna reveal a surprising role for histone deacetylase 1 (HDAC1) - a member of a family of chromatin modifying proteins - in the development of skin tumors.

18 Nov 2013

Eisai partners with NewBridge Pharmaceuticals to market Halaven drug in Middle East

Eisai announces today that Halaven (eribulin) will be marketed in selected countries within the Middle East region through a new partnership between Eisai EMEA (Europe, the Middle East, Africa, Russia and Oceania) and NewBridge Pharmaceuticals.

18 Nov 2013

Researchers explain new function of 2 key molecules involved in tumor progression

Researchers from IMIM (Hospital del Mar Medical Research Institute) lead by Dr. Sandra Peir- have described a new function for two key molecules involved in tumor progression.

16 Nov 2013

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

The Joint Center for Cancer Precision Medicine, a collaborative initiative among Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, and the Broad Institute of MIT and Harvard, has been established to create "precision medicine treatment pathways" for patients with advanced cancers and to speed the development of personalized therapies.

16 Nov 2013

Tumor News and Research

Smoking influences survival of nasopharyngeal carcinoma patients

Findings show how cancer and aging are tightly interconnected

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

DNA-damaging drug and MK2 inhibitor combination could be effective against cancer

Tasquinimod drug effective for men with metastatic castration-resistant prostate cancer

First patients enrolled in EF-21 Study of NovoTTF Therapy for brain metastases from NSCLC cancer

Serametrix launches new MDSC-based blood test for cancer patients

Loyola University initiates clinical trial of vaccine that trains immune system to fight melanoma

UC San Diego study suggests racial inequality leads to higher mortality in cancer patients

Boston Scientific's Direxion Torqueable Microcatheter receives FDA clearance and CE Mark approval

Patients treated with high-risk endoscopic procedure less likely to be admitted in hospital

Study confirms therapeutic potential of inhibiting Aurora-A in cancer treatment

Findings may help scientists better understand prognosis of advanced prostate cancer

Extract from bitter melon may have therapeutic qualities to treat head and neck cancer

Obese women face increased risk of developing aggressive sub-type of breast cancer

Medical–surgical integration ‘boosts neoadjuvant chemotherapy use for bladder cancer’

Scientists reveal surprising role for HDAC1 proteins in development of skin tumors

Eisai partners with NewBridge Pharmaceuticals to market Halaven drug in Middle East

Researchers explain new function of 2 key molecules involved in tumor progression

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

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