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Study offers insight into molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

7 Mar 2022

World's largest genetic study reveals fresh details about severe Covid-19

The world's largest study of the genetics of critical Covid-19, involving more than 57,000 people, has revealed fresh details about some of the biological mechanisms behind the severe form of the disease.

7 Mar 2022

Slowing down the DNA replication speed increases cell reprogramming efficiency

Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only.

7 Mar 2022

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

Many people aspire to live longer, healthier lives. A researcher at Baylor College of Medicine, Dr. Rajagopal Sekhar, associate professor of medicine in the section of endocrinology, diabetes and metabolism, has been studying aging for the past 20 years to better understand its biological underpinnings and develop nutritional strategies to promote healthy aging.

7 Mar 2022

Researchers examine how structural violence can set the stage for poorer leukemia outcomes

Black and Hispanic people with acute myeloid leukemia in greater Chicago were more likely to die from the disease than their non-Hispanic white counterparts, with a 59% and 25% greater risk, respectively, according to a new study led by University of Illinois Chicago researchers.

7 Mar 2022

Study to examine the risks for brain disorders from repetitive head impacts in contact sports

Internationally-renowned researchers from Boston University and the University of California, San Francisco) are launching a new study, called the Head Impact & Trauma Surveillance Study (HITSS).

7 Mar 2022

New, highly promising strategy to overcome a key cause of cancer deaths

A research team led by scientists at Albert Einstein College of Medicine has devised a novel and highly promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them.

7 Mar 2022

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Pancreatic cancer is one of the most aggressive and deadly tumor types and notorious for its resistance to virtually all types of treatment, including newer immunotherapies.

7 Mar 2022

Researchers find considerable differences in performance between different artificial heart valves

Researchers at Karolinska Institutet in Sweden have studied long-term morbidity and mortality in individuals who have had different models of biological heart valves implanted.

7 Mar 2022

Specific variant of the HLA-DPB1 gene linked with poor response to allergen immunotherapy

Although sublingual immunotherapy (SLIT) has become an effective treatment option for many allergies, about 20-30% of patients don’t respond to SLIT for Japanese cedar pollinosis–a highly common disease.

7 Mar 2022

Clinical outcomes of regdanvimab usage in patients with mild to moderate COVID-19

Researchers evaluated the effectiveness of regdanvimab on clinical outcomes in patients with mild to moderate COVID-19.

7 Mar 2022

World Trade Center responders have increased levels of mutations that escalate blood cancer risk

Scientists from Vanderbilt-Ingram Cancer Center (VICC) collaborated with researchers from New York to determine that 9/11 first responders to the World Trade Center have increased levels of mutations that escalate their risk for blood cancers or cardiovascular disease, according to a study published March 7 in Nature Medicine.

7 Mar 2022

New insight about how optimism may promote good health as people age

Don't worry, be happy," is more than just song lyrics. A growing body of evidence supports an association between optimism and healthy aging, but it is unclear how optimism impacts health.

7 Mar 2022

Physicians' knowledge, attitudes, and preventative practices regarding the COVID-19 pandemic

Researchers conducted a global survey to assess the knowledge, attitudes, and practices of physicians towards COVID-19.

7 Mar 2022

What does the Future Look Like for Patient Centricity within Clinical Trials?

In this interview, we speak to Dr. Paresh Malhotra about what the future holds for patient centricity within clinical trials, and the benefits for this focus.

7 Mar 2022

Charts paint a grim picture 2 years into the coronavirus pandemic

The coronavirus pandemic is now stretching into its third year, a grim milestone that calls for another look at the human toll of covid-19, and the unsteady progress in containing it.

7 Mar 2022

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

A new study discusses the outcomes of idiopathic pulmonary fibrosis patients with confirmed SARS-CoV-2 infection.

6 Mar 2022

Combating COVID cytokine storm with targeted nucleic acid therapies

Researchers examine current nucleic acid-based treatments against COVID-19 and their methods of action.

6 Mar 2022

New technique can upregulate specific genes without permanently altering the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

6 Mar 2022

$20 million scientific research initiative focuses on disparities in maternal-infant heart health

Poor heart health, especially among women of color, puts both mothers-to-be and their infants at risk, with heart disease causing more than one in four pregnancy-related deaths (26.5%) in the U.S., according to the American Heart Association Heart Disease and Stroke Statistics 2022 Update.

6 Mar 2022

Medicine News and Research

Study offers insight into molecular biology of the brain in bipolar disorder patients

World's largest genetic study reveals fresh details about severe Covid-19

Slowing down the DNA replication speed increases cell reprogramming efficiency

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

Researchers examine how structural violence can set the stage for poorer leukemia outcomes

Study to examine the risks for brain disorders from repetitive head impacts in contact sports

New, highly promising strategy to overcome a key cause of cancer deaths

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Researchers find considerable differences in performance between different artificial heart valves

Specific variant of the HLA-DPB1 gene linked with poor response to allergen immunotherapy

Clinical outcomes of regdanvimab usage in patients with mild to moderate COVID-19

World Trade Center responders have increased levels of mutations that escalate blood cancer risk

New insight about how optimism may promote good health as people age

Physicians' knowledge, attitudes, and preventative practices regarding the COVID-19 pandemic

What does the Future Look Like for Patient Centricity within Clinical Trials?

Charts paint a grim picture 2 years into the coronavirus pandemic

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

Combating COVID cytokine storm with targeted nucleic acid therapies

New technique can upregulate specific genes without permanently altering the genome

$20 million scientific research initiative focuses on disparities in maternal-infant heart health

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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