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Study finds inherited GATA3 gene variation increases risk of developing pediatric leukemia

Research led by St. Jude Children's Research Hospital scientists has linked an inherited gene variation to a nearly four-fold increased risk of developing a pediatric acute lymphoblastic leukemia (ALL) subtype that is associated with a poor outcome.

21 Oct 2013

Clarified role of signal-relay proteins may help explain spread of cancer

Cell biologists at The Johns Hopkins University have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.

21 Oct 2013

Phase 2b study of JAK3 inhibitor VX-509 shows improvement in people with active RA

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced 12-week results from an ongoing Phase 2b study of VX-509, an investigational oral, selective Janus kinase 3 (JAK3) inhibitor, dosed once or twice daily in people with active rheumatoid arthritis (RA) taking methotrexate

19 Oct 2013

Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body.

19 Oct 2013

Study: Skin tanning gene linked to higher risk for testicular cancer in white men

A gene important in skin tanning has been linked to higher risk for testicular cancer in white men, according to a study led by scientists from the U.S. National Institutes of Health and the University of Oxford in England.

19 Oct 2013

New prognostic tool forecasts survival of patients with advanced prostate cancer

For men with advanced prostate cancer that has progressed after taking hormones and undergoing chemotherapy, getting an accurate prognosis is critical to determine the next steps for treatment.

19 Oct 2013

Research: Hypermutation in cancer is more frequent in inactive X chromosome

Every case of cancer originates from changes in a person's genetic material (mutations). These usually occur as "somatic mutations" in individual cells during an individual's lifetime, rather than being inherited from a person's parents.

19 Oct 2013

Genalyte Gets Grant From NCI To Develop Biomarker Panel For Cancer

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18 Oct 2013

ARIAD discontinues Phase 3 EPIC trial of Iclusig in patients with chronic myeloid leukemia

ARIAD Pharmaceuticals, Inc. today announced that it is discontinuing the Phase 3 EPIC (Evaluation of Ponatinib versus Imatinib in Chronic Myeloid Leukemia) trial of Iclusig (ponatinib) in patients with newly diagnosed chronic myeloid leukemia.

18 Oct 2013

Genalyte receives NCI grant to develop biomarker panel to profile TAA autoantibodies

Genalyte, Inc., today announced that it has received a $1 million SBIR grant from the National Cancer Institute to develop a biomarker panel to profile tumor antigen-associated autoantibodies.

18 Oct 2013

Surefire Medical announces launch of new infusion system

Surefire Medical, Inc., today announced the launch of a new, enhanced infusion system – the Surefire Infusion System mT – designed to treat vessels as small as 2mm to 3.5mm in interventional direct-to-target embolization procedures.

18 Oct 2013

GenSpera to present G-202 Phase I trial in hepatocellular carcinoma at EORTC-NCI-AACR Symposium

GenSpera, Inc. (OTCBB:GNSZ) announced that Devalingam Mahalingam, MD, PhD, principal investigator of the G-202 Phase II trial in hepatocellular carcinoma, will present data from the G-202 Phase I clinical trial at the EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Boston, MA on Monday, October 21st.

18 Oct 2013

Gene variations in response to injury can impact clinical outcomes in TBI

Subtle variations in genes that regulate a person's inflammatory response to injury can impact clinical outcomes in TBI, according to a new study published in Journal of Neurotrauma.

18 Oct 2013

New recovery program for abdominal surgery patients improves recovery process

A new recovery program for abdominal surgery patients at University of Virginia Health System is helping patients go home sooner while making them more comfortable both before and after surgery.

18 Oct 2013

Ultrasound prior to thyroidectomy important for planning surgery

Ultrasound imaging is commonly used to diagnose and evaluate patients with differentiated thyroid cancer, and to determine whether the disease has spread to lymph nodes in the neck that should be removed at the time of thyroidectomy.

17 Oct 2013

Researchers find novel drug target for anaplastic thyroid carcinomas

Anaplastic thyroid carcinomas are aggressive tumors that do not respond to traditional radio- or chemotherapeutic agents, and there currently is no cure or effective treatment available. Median survival from diagnosis is 5 months, and although ATC accounts for only 1.7% of all thyroid cancers in the U.S., it is responsible for a large proportion of thyroid cancer-related deaths.

17 Oct 2013

Scientists identify 127 mutated genes that appear to drive development of tumors in the body

Examining 12 major types of cancer, scientists at Washington University School of Medicine in St. Louis have identified 127 repeatedly mutated genes that appear to drive the development and progression of a range of tumors in the body. The discovery sets the stage for devising new diagnostic tools and more personalized cancer treatments.

17 Oct 2013

New $1.9M research grant to support investigators to detect tumors in earliest stages of formation

The National Cancer Institute's new Provocative Questions research funding program has awarded a prestigious grant to researchers at the Case Comprehensive Cancer Center and Case Western Reserve University's Schools of Medicine and Engineering to study tumor detection at the earliest stages of growth.

16 Oct 2013

Breast cancer patients receiving nerve block with general anesthesia have less cancer recurrence

Breast cancer patients who received the combination of a nerve block with general anesthesia for their breast cancer surgery had less cancer recurrence and were three times less likely to die than those who received only general anesthesia, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

16 Oct 2013

Simple blood test can help diagnose early-stage lung and prostate cancers

Early-stage lung and prostate cancers as well as their recurrence can be detected with a simple blood test, according to a study presented at the ANESTHESIOLOGY 2013 annual meeting.

16 Oct 2013

Tumor News and Research

Study finds inherited GATA3 gene variation increases risk of developing pediatric leukemia

Clarified role of signal-relay proteins may help explain spread of cancer

Phase 2b study of JAK3 inhibitor VX-509 shows improvement in people with active RA

Wnt5A signaling pathway helps researchers determine who may respond to BRAF inhibitors

Study: Skin tanning gene linked to higher risk for testicular cancer in white men

New prognostic tool forecasts survival of patients with advanced prostate cancer

Research: Hypermutation in cancer is more frequent in inactive X chromosome

Genalyte Gets Grant From NCI To Develop Biomarker Panel For Cancer

ARIAD discontinues Phase 3 EPIC trial of Iclusig in patients with chronic myeloid leukemia

Genalyte receives NCI grant to develop biomarker panel to profile TAA autoantibodies

Surefire Medical announces launch of new infusion system

GenSpera to present G-202 Phase I trial in hepatocellular carcinoma at EORTC-NCI-AACR Symposium

Gene variations in response to injury can impact clinical outcomes in TBI

New recovery program for abdominal surgery patients improves recovery process

Ultrasound prior to thyroidectomy important for planning surgery

Researchers find novel drug target for anaplastic thyroid carcinomas

Scientists identify 127 mutated genes that appear to drive development of tumors in the body

New $1.9M research grant to support investigators to detect tumors in earliest stages of formation

Breast cancer patients receiving nerve block with general anesthesia have less cancer recurrence

Simple blood test can help diagnose early-stage lung and prostate cancers

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