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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Certain fragments of DNA shed by tumors can be used to non-invasively screen for early-stage cancers

Certain fragments of DNA shed by tumors into the bloodstream can potentially be used to non-invasively screen for early-stage cancers, monitor responses to treatment and help explain why some cancers are resistant to therapies, according to results of an international study led by Johns Hopkins Kimmel Cancer Center investigators.

20 Feb 2014

Babies who develop leukemia appear to inherit strong genetic predisposition to disease

Babies who develop leukemia during the first year of life appear to inherit an unfortunate combination of genetic variations that can make the infants highly susceptible to the disease, according to a new study at Washington University School of Medicine in St. Louis and the University of Minnesota.

20 Feb 2014

Scientists produce reliable set of genotypes to benchmark human genome sequencing

Led by biomedical engineer Justin Zook of the National Institute of Standards and Technology, a team of scientists from Harvard University and the Virginia Bioinformatics Institute of Virginia Tech has presented new methods to integrate data from different sequencing platforms, thus producing a reliable set of genotypes to benchmark human genome sequencing.

19 Feb 2014

Researchers discover protein for treatment of anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma (ATC) is an aggressive type of cancer with a poor prognosis for which there is currently no effective treatment. Researchers from the National University of Singapore (NUS) have discovered for the first time that an epithelial basement membrane protein, called laminin-5 gamma-2 (LAMC2), has the potential to be an ideal target for the treatment of ATC.

19 Feb 2014

Discovery could lead to improved early detection, prevention strategies for sudden cardiac death

UC Irvine researchers have found a specific genetic flaw that is connected to sudden death due to heart arrhythmia - a leading cause of mortality for adults around the world.

18 Feb 2014

Scientists develop mathematical method for classifying forms of glioblastoma

Scientists at The Wistar Institute have developed a mathematical method for classifying forms of glioblastoma, an aggressive and deadly type of brain cancer, through variations in the way these tumor cells "read" genes. Their system was capable of predicting the subclasses of glioblastoma tumors with 92 percent accuracy. With further testing, this system could enable physicians to accurately predict which forms of therapy would benefit their patients the most.

18 Feb 2014

Pathway Genomics announces launch of Hereditary Colorectal Cancer DNA Insight genetic test

Pathway Genomics Corporation, a San Diego-based CLIA and CAP accredited clinical laboratory that offers genetic testing services worldwide, today announced the launch of Hereditary Colorectal Cancer DNA Insight, the company's premier hereditary cancer genetic test. Based on a simple saliva sample, the test uses next-generation sequencing (NGS) technology to identify gene alterations or mutations that increase a patient's risk of developing certain types of cancer.

18 Feb 2014

The Future of DNA Sequencing

In this interview, Barret Bready discusses the current gold standards in DNA sequencing and how the Nabsys platform is revolutionizing this process.

18 Feb 2014

Bioline enters Epigenetics field with launch of new EPIK product range

Bioline, The PCR Company, a wholly-owned subsidiary of Meridian Bioscience, Inc., announces that it has entered the rapidly growing Epigenetics field, with the launch of the first kits in the new EPIK™ product range; EPIK™ Fast Quantification Kit and EPIK™ Amplification Kit.

18 Feb 2014

Small non-coding RNAs can help predict individuals with breast cancer

Small non-coding RNAs can be used to predict if individuals have breast cancer conclude researchers who contribute to The Cancer Genome Atlas project. The results, which are published in EMBO reports, indicate that differences in the levels of specific types of non-coding RNAs can be used to distinguish between cancerous and non-cancerous tissues. These RNAs can also be used to classify cancer patients into subgroups of individuals that have different survival outcomes.

18 Feb 2014

NUS researchers discover promising treatment for anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma is an aggressive type of cancer with a poor prognosis for which there is currently no effective treatment. Researchers from the National University of Singapore have discovered for the first time that an epithelial basement membrane protein, called laminin-5 gamma-2 (LAMC2), has the potential to be an ideal target for the treatment of ATC.

18 Feb 2014

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

A common compound known to fight lymphoma and skin conditions actually has a second method of action that makes it particularly deadly against certain aggressive breast tumors, researchers at Duke Medicine report.

18 Feb 2014

Scientists measure how well football helmet designs protected against traumatic brain injury

A new study finds that football helmets currently used on the field may do little to protect against hits to the side of the head, or rotational force, an often dangerous source of brain injury and encephalopathy.

18 Feb 2014

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

The elusive progenitor cells that give rise to innate lymphoid cells-a recently discovered group of infection-fighting white blood cells-have been identified in fetal liver and adult bone marrow of mice, researchers from the University of Chicago report early online in the journal Nature.

14 Feb 2014

Researchers reveal how genome-editing tool works as 'guided missile' to correct errors in genetic code

Researchers from the Broad Institute and MIT have teamed up with colleagues from the University of Tokyo to form the first high definition picture of the Cas9 complex - a key part of the CRISPR-Cas system used by scientists as a genome-editing tool to silence genes and probe the biology of cells. Their findings, which are reported this week in Cell, are expected to help researchers refine and further engineer the tool to accelerate genomic research and bring the technology closer to use in the treatment of human genetic disease.

13 Feb 2014

FDA grants full approval of SYNRIBO for injection

Teva Pharmaceutical Industries Ltd. today announced that the U.S. Food and Drug Administration has granted full approval of SYNRIBO (omacetaxine mepesuccinate) for injection. This oncology portfolio product received an accelerated approval in October, 2012 with additional clinical trial data required to fulfill post marketing requirements set forth by the FDA.

13 Feb 2014

Novogene purchases HiSeq X Ten sequencing system from Illumina

Illumina, Inc. (NASDAQ:ILMN) today announced that Novogene (www.novogene.cn), a leading genomics service provider based in Beijing, China, purchased one HiSeq X Ten.

From Illumina, Inc. 13 Feb 2014

Researchers identify effective target for human autoimmune disease

Researchers at King's College London have identified a new gene (PIM1), which could be an effective target for innovative treatments and therapies for the human autoimmune disease, psoriasis.

13 Feb 2014

Commonly used disinfectants do not kill human papillomavirus, say researchers

Commonly used disinfectants do not kill human papillomavirus (HPV) that makes possible non-sexual transmission of the virus, thus creating a need for hospital policy changes, according to researchers from Penn State College of Medicine and Brigham Young University.

13 Feb 2014

Scientists explain why women with dense breast tissue at greater risk of developing breast cancer

Scientists from The University of Manchester working with IBM Research have identified a key biological mechanism that for the first time explains why women with dense breast tissue are at greater risk of developing breast cancer.

12 Feb 2014

DNA News and Research

Further Reading

Certain fragments of DNA shed by tumors can be used to non-invasively screen for early-stage cancers

Babies who develop leukemia appear to inherit strong genetic predisposition to disease

Scientists produce reliable set of genotypes to benchmark human genome sequencing

Researchers discover protein for treatment of anaplastic thyroid carcinoma

Discovery could lead to improved early detection, prevention strategies for sudden cardiac death

Scientists develop mathematical method for classifying forms of glioblastoma

Pathway Genomics announces launch of Hereditary Colorectal Cancer DNA Insight genetic test

The Future of DNA Sequencing

Bioline enters Epigenetics field with launch of new EPIK product range

Small non-coding RNAs can help predict individuals with breast cancer

NUS researchers discover promising treatment for anaplastic thyroid carcinoma

Researchers detail how psoralen blocks signaling pathway of HER2-positive cancers

Scientists measure how well football helmet designs protected against traumatic brain injury

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

Researchers reveal how genome-editing tool works as 'guided missile' to correct errors in genetic code

FDA grants full approval of SYNRIBO for injection

Novogene purchases HiSeq X Ten sequencing system from Illumina

Researchers identify effective target for human autoimmune disease

Commonly used disinfectants do not kill human papillomavirus, say researchers

Scientists explain why women with dense breast tissue at greater risk of developing breast cancer

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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