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Vitamin C injections slow tumor growth in mice

High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National Institutes of Health (NIH) report in the August 5, 2008, issue of the Proceedings of the National Academy of Sciences.

4 Aug 2008

Methadone shows promise against leukemia

Researchers in Germany have discovered that methadone, an agent used to break addiction to opioid drugs, has surprising killing power against leukemia cells, including treatment resistant forms of the cancer.

3 Aug 2008

Researchers discover novel kind of learning gene

Scientists at the Freie Universität Berlin have come one step closer to unraveling the molecular basis of learning. A team led by neurobiologist Bjorn Brembs has discovered the first gene for operant conditioning in the fruit fly Drosophila.

3 Aug 2008

Scientists develop ultra-sensitive optical protein sensor, a first for a salivary diagnostic test

For people who dislike needles, medical tests that require a drop of saliva instead of a vial of blood will one day make a trip to a doctor or dentist much easier. But as scientists now construct the first of these saliva tests for early signs of cancer and other diseases, they continue to push the technological envelope in interesting ways.

3 Aug 2008

An unsuspected weakness in tuberculosis - potential drug target

With antibiotic resistance on the rise, tuberculosis is emerging as a bigger global health threat than ever before.

31 Jul 2008

Eroded telomeres are behind dyskeratosis congentia aging syndrome

Each time a cell divides, the protective caps at the ends of chromosomes shorten - and when these caps are gone, so are we. Now, by using an unconventional strategy to shorten telomeres in mice, researchers at Rockefeller University have not only created the first faithful mouse model for studying a rare yet fatal premature aging syndrome, but they have revealed the molecular defect behind the disease.

30 Jul 2008

Cell mechanism discovery may lead to new treatments for cystic fibrosis, other inherited diseases

Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells - sometimes too well. The breakthrough has significant implications for the development of new treatments for cystic fibrosis (CF) and some other hereditary diseases, the researchers say. Their results were published July 25 in the journal Science.

29 Jul 2008

Markers in blood and spinal fluid, and a new imaging agent, show promise for early detection of Alzheimer's

With the continued aging of the population and the growing epidemic of Alzheimer's, early detection of the disease is crucial for risk assessment, testing new therapies, and eventual early intervention with better drugs, once they are developed. Four studies reported today at the Alzheimer's Association's 2008 International Conference on Alzheimer's Disease (ICAD 2008) in Chicago bring us closer to that goal of early detection by describing advances in biomarkers.

29 Jul 2008

New biomarker for early cancer detection? Research reveals that 'microRNA' may fit the bill

Scientists at Fred Hutchinson Cancer Research Center have discovered that microRNAs - molecular workhorses that regulate gene expression - are released by cancer cells and circulate in the blood, which gives them the potential to become a new class of biomarkers to detect cancer at its earliest stages. Muneesh Tewari, M.D., Ph.D., and colleagues describe their findings in the July 28 issue of the Proceedings of the National Academy of Sciences.

29 Jul 2008

New antibiotics to fight MRSA

A new paper by Shahriar Mobashery, Navari Family Professor in Life Sciences at the University of Notre Dame, and researchers in his lab provides important insights into promising new antibiotics aimed at combating MRSA.

28 Jul 2008

Viagra and Levitra ED drugs shown to allow more chemo to reach brain tumors

In a study using laboratory animals, researchers found that medications commonly prescribed for erectile dysfunction opened a mechanism called the blood-brain tumor barrier and increased delivery of cancer-fighting drugs to malignant brain tumors.

28 Jul 2008

Clinical trials to examine mushrooms' cancer-fighting properties

The role of mushrooms in reducing the risk of breast and prostate cancers and in stunting the growth of these cancers will be tested shortly with the start of human clinical trials at the City of Hope research centre in California.

27 Jul 2008

Could new molecules - polyoxometalates - help treat cancer?

A fruitful collaboration between chemists and biologists has made it possible to identify the effects of a new class of molecules, polyoxometalates, primarily composed of metals and oxygen.

27 Jul 2008

Researchers find key mechanism of cell damage in aging and disease

Researchers have taken a first snapshot of how a class of highly reactive molecules inflicts cellular damage as part of aging, heart disease, stroke, cancer, diabetes, kidney disease and Alzheimer's disease to name a few. According to a study published today in the journal Cell, researchers have discovered a tool that can monitor related damage and determine the degree to which antioxidant drugs effectively combat disease.

24 Jul 2008

Abiraterone new drug for aggressive prostate cancer the best thing in 70 years

Scientists say a new drug which treats aggressive prostate cancer is possibly the most significant development in the field for 70 years.

22 Jul 2008

China Medicine Corporation grated Australian patent for recombinant Aflatoxin Detoxifizyme

China Medicine Corporation announced today that it obtained a patent from Australia Patent Office for recombinant Aflatoxin Detoxifizyme (rADTZ). The patent is valid through January 13, 2025.

17 Jul 2008

MedMira Inc. awarded US patent for rapid test technology

MedMira Inc. announced today that it received a Notice of Allowance from the United States Patent and Trademark Office for its rapid flow-through test (RFT) methodology, the technology platform its rapid tests are built on.

17 Jul 2008

EpiCept and GNI partner to develop anti-viral hepatitis drug in Asia

GNI Ltd and EpiCept Corporation have announced that they have reached agreement to develop a new therapeutic drug, EP1013, in Asia, Australia, and New Zealand, for late-stage viral infection-induced hepatitis. EpiCept will retain the rights in the rest of the world. GNI’s wholly owned subsidiary, Shanghai Genomics, will start preparation for pre-IND and clinical development in China immediately.

17 Jul 2008

Superbug breakthrough

The week the government's chief medical officer for England, Sir Liam Donaldson, has announced that the NHS aims to create immunisation against two of the most common superbugs, MRSA and Clostridium difficile, within the next decade. But a research team led by University of Sunderland scientists has made a major breakthrough in the fight against a deadly hospital infection which kills tens of thousands of people every year, and it will be available within the next year.

17 Jul 2008

AFFiRiS GmbH alzheimer's vaccine progress

In the clinical phase I trial AFF001, AFFiRiS GmbH has now recruited the 24 Alzheimer patients planned for this trial. The trial aims to investigate the tolerability and safety of an innovative Alzheimer's vaccine (AFFITOPE AD01).

16 Jul 2008

Enzyme News and Research

Vitamin C injections slow tumor growth in mice

Methadone shows promise against leukemia

Researchers discover novel kind of learning gene

Scientists develop ultra-sensitive optical protein sensor, a first for a salivary diagnostic test

An unsuspected weakness in tuberculosis - potential drug target

Eroded telomeres are behind dyskeratosis congentia aging syndrome

Cell mechanism discovery may lead to new treatments for cystic fibrosis, other inherited diseases

Markers in blood and spinal fluid, and a new imaging agent, show promise for early detection of Alzheimer's

New biomarker for early cancer detection? Research reveals that 'microRNA' may fit the bill

New antibiotics to fight MRSA

Viagra and Levitra ED drugs shown to allow more chemo to reach brain tumors

Clinical trials to examine mushrooms' cancer-fighting properties

Could new molecules - polyoxometalates - help treat cancer?

Researchers find key mechanism of cell damage in aging and disease

Abiraterone new drug for aggressive prostate cancer the best thing in 70 years

China Medicine Corporation grated Australian patent for recombinant Aflatoxin Detoxifizyme

MedMira Inc. awarded US patent for rapid test technology

EpiCept and GNI partner to develop anti-viral hepatitis drug in Asia

Superbug breakthrough

AFFiRiS GmbH alzheimer's vaccine progress

Measuring Drug-Target Residence Times with Biochemical Assays eBook

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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