Muscle News and Research

RSS

Mesoblast receives FDA clearance for heart attack stem cell trial

Australia's adult stem cell company, Mesoblast Limited has announced that the United States Food and Drug Administration (US FDA) has cleared the Investigational New Drug Submission (IND) of its US-based sister company, Angioblast Systems Inc., to commence a Phase 2 clinical trial of its allogeneic, or 'off-the-shelf', adult stem cells for patients with heart attacks.

4 May 2007

BioMarin starts phase 2a study of 6R-BH4 in sickle cell disease

BioMarin Pharmaceutical has announced that the first patient has initiated treatment in the Phase 2a clinical study of 6R-BH4 (sapropterin dihydrochloride) for the treatment of sickle cell disease (SCD).

4 May 2007

Reclast found to cause abnormal heart rhythms

An osteoporosis drug with the potential to cut the risk of spine fractures by 70 percent and the chance of hip fractures by 41 percent, has been found to have an adverse side effect on some women.

3 May 2007

Infliximab fails to improve chronic obstructive pulmonary disease symptoms

A promising anti-inflammatory drug failed to improve symptoms of moderate to severe chronic obstructive pulmonary disease, or COPD, in a large, multi-center trial.

2 May 2007

New treatments have major impact on heart failure rates

Deaths from severe heart attacks following admission to hospital have nearly halved in six years as a result of advances in medical treatment.

2 May 2007

1758 cases of malaria reported in UK travellers in 2006

1386 of the cases were due to the potentially fatal Plasmodium falciparum which is a major international health risk and which kills more than a million people a year in Africa. 219 were due to Plasmodium vivax which causes a debilitating disease, but is rarely fatal.

2 May 2007

Laparoscopic gastric banding surgery improves insulin resistance

A new study examining the overall and gender-related effects of laparoscopic gastric banding surgery (LGBS) on insulin resistance, body composition, and metabolic risk markers six months post-surgery has found significant improvements in insulin resistance.

2 May 2007

Higher calcium and vitamin D intake linked to brain lesions in seniors

Elderly men and women who consumed higher levels of calcium and vitamin D are significantly more likely to have greater volumes of brain lesions, regions of damage that can increase risk of cognitive impairment, dementia, depression and stroke.

2 May 2007

Green tea shows potential for HIV-associated dementia prevention

A compound derived from green tea greatly diminished the neurotoxicity of proteins secreted by the human immunodeficiency virus, suggesting a new approach to the prevention and treatment of HIV-associated dementia, also known as AIDS dementia complex.

2 May 2007

Evidence of very early onset defective bone mineralization in the lumbar spine revealed in children with cystic fibrosis

In a study of children with cystic fibrosis, French researchers found evidence of very early onset defective bone mineralization in the lumbar spine that was not caused by either nutritional status or lung disease.

2 May 2007

Ultra fast and ultra active: the strange life of the extraocular muscles

The eye, often called the window to the soul, may become a window to the mysteries of muscular dystrophy, a debilitating muscle disease that often leads to death in early adulthood.

2 May 2007

CleveMed receives approval to market motor assessment system

Cleveland Medical Devices has received Food and Drug Administration (FDA) clearance to market Kinesia, a quantitative motor assessment system.

2 May 2007

Virtual reality device helps multiple sclerosis patients walk

Technion-Israel Institute of Technology scientists have created a virtual reality device that combines auditory and visual feedback to improve walking speed and stride length in patients suffering from Multiple Sclerosis (MS) and Parkinson's disease.

1 May 2007

Mechanisms of glucose homeostasis and early diabetes

Glucose homeostasis, the appropriate balancing of blood sugar levels, is impaired early in patients who become diabetic, causing life-threatening complications such as kidney failure and heart attacks.

1 May 2007

Exercise helps patients regain the ability to swallow

Just thinking about swallowing makes it harder to do. Head and neck cancer, a stroke, brain tumor, brain injury or even a tracheostomy tube and mechanical ventilation needed to sustain life can make it impossible.

1 May 2007

Identifying cardiorespiratory neurocircuitry involved in central command during exercise in humans

For almost one hundred years the brain's ,central command, system , whose charge includes controlling the body's cardiorespiratory response to exercise , has been pursued. Animal experiments and functional imaging studies have provided clues to the location of this system, but the underlying electrophysiological activity has never been measured.

30 Apr 2007

Scientists discover pathway that promotes muscle cell survival in mice

Scientists at the Salk Institute for Biological Studies have identified an enzyme that pumps up a cell's ability to maintain healthy muscle and restores normal muscle function in genetically engineered mice with weak muscles.

30 Apr 2007

FDA approves INVEGA treatment for schizophrenia

The U.S. Food and Drug Administration (FDA) has approved INVEGA (paliperidone) Extended-Release Tablets, a new once-daily, atypical antipsychotic, for the long-term maintenance treatment of schizophrenia.

30 Apr 2007

Ratio of women stricken with MS rockets by 50% each decade

According to a study in the United States although women have always had a greater susceptibility for developing Multiple Sclerosis (MS) than men, the numbers have rocketed in the last six decades.

29 Apr 2007

New prosthetic limbs allow for eight degrees of freedom

An international team led by the Johns Hopkins University Applied Physics Laboratory in Laurel, Md., has developed a prototype of the first fully integrated prosthetic arm that can be controlled naturally and provide sensory feedback, and allows for eight degrees of Freedom -- a level of control far beyond the current state of the art for prosthetic limbs.

27 Apr 2007