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Blocked brain enzyme shows potential as target for appetite control, weight loss and blood sugar management

Imagine being able to tone down appetite and promote weight loss, while improving the body's ability to handle blood sugar levels.

6 May 2008

Researchers find way to make tumor cells more sensitive to hyperthermia-enhanced radiation therapy

Tumors have a unique vulnerability that can be exploited to make them more sensitive to heat and radiation, researchers at Washington University School of Medicine in St. Louis report.

6 May 2008

Clockwork PCR including sample prep

Analysis and diagnosis in a chip format are coming of age, but their practical application has been limited because until now, the sample usually had to be prepared separately and on a nonminiaturized scale.

6 May 2008

Geron Corporation awarded UK grant funding for human embryonic stem cell research

Geron Corporation announced today two grant awards to the University of Edinburgh from the UK Stem Cell Foundation, with funding from the Medical Research Council and Scottish Enterprise.

6 May 2008

New chemicals shield 'genome guardian'

Cancer Research UK scientists have discovered a potent group of chemicals that protect p53 - a major anti-tumour gene - from destruction, a study published in Cancer Cell* today (Monday) reveals.

6 May 2008

Discovery of tenovins could lead to cancer cure

Scientists in Scotland have discovered a group of chemicals which protect one of the body's most important anti-cancer genes from destruction.

6 May 2008

Kidney disease substantially worsens in a fourth of African Americans despite therapy for hypertension

The best available treatment for chronic kidney disease from high blood pressure did not keep the disease from substantially worsening in about a fourth of African-Americans studied, according to long-term results of a National Institutes of Health study published April 28, 2008, in the Archives of Internal Medicine.

5 May 2008

Study identifies new mechanism linking activation of key heart enzyme and oxidative stress

A study, led by University of Iowa researchers, reveals a new dimension for a key heart enzyme and sheds light on an important biological pathway involved in cell death in heart disease.

1 May 2008

Breakthrough compound could lead to new class of antihypertensive drugs

University of Florida researchers have identified a drug compound that dramatically lowers blood pressure, improves heart function and - in a remarkable finding - prevents damage to the heart and kidneys in rats with persistent hypertension

1 May 2008

Turning on cell-cell communication wipes out staph biofilms

University of Iowa researchers have succeeded in wiping out established biofilms of Staphylococcus aureus (staph) by hijacking one of the bacteria's own regulatory systems.

30 Apr 2008

Aspirin and other NSAIDs could lower the risk of breast cancer

Taking aspirin on a daily basis may lower women's risk of a particular type of breast cancer, according to results published in BioMed Central's open access journal Breast Cancer Research.

30 Apr 2008

Hydrogen sulphide may be involved in regulating blood pressure

Hydrogen sulphide is a gas most commonly associated with the smell of stink bombs, sewage and rotten eggs, but a team of researchers from the Peninsula Medical School in the South West of England and King's College London have now identified a role for this gas in regulating blood pressure, according to research published in the leading science journal "Circulation".

29 Apr 2008

Popular blood pressure drugs could hold the key to weight loss

A study by Australian scientists has indicated that some of the most commonly used blood pressure medications could help people lose weight and body fat and reduce the likelihood of them developing diabetes.

29 Apr 2008

Scientists discover way to increase metabolism for weight loss

Scientists from Melbourne's Howard Florey Institute have discovered a way to aid weight loss and reduce the likelihood of developing diabetes by manipulating fat cells to increase the body's metabolism.

28 Apr 2008

Epigenetic research uncovers new targets for modification enzymes

Enzymes regulating genetic expression can be just as important as the genome itself, increasing evidence shows.

27 Apr 2008

Maitake mushrooms lead to breakthrough in protein research

Using an enzyme of the Japanese mushroom Grifola frondosa (Maitake or dancing mushroom), proteins can be identified without knowing the organism's genetic composition.

26 Apr 2008

Coffee protects some women against breast cancer

Depending on which variant of a certain gene a woman has, a coffee consumption rate of at least two-three cups a day can either reduce the total risk of developing breast cancer or delay the onset of cancer. This is shown in new research from Lund University and Malmo University in Sweden.

24 Apr 2008

DNA vaccines may offer hope in multiple sclerosis

Authors from the VA North Texas Health Care System Neurology Section and the Department of Neurology at the University of Texas Southwestern Medical Center at Dallas have highlighted the potential benefits for DNA-based vaccine administration in patients with multiple sclerosis (MS).

24 Apr 2008

Pralatrexate for T-cell lymphoma

The fifth leading cause of cancer in the United States, lymphoma is made up of more than 40 rare and highly diverse diseases that target the body's lymphatic system. Lymphomas include both one of the fastest growing cancers -- Burkitt's lymphoma, which can double in size in as little as a day -- and one of the slowest, chronic lymphocytic leukemia (CLL).

24 Apr 2008

AMPK signaling helps explain how cell growth is inhibited when nutrients are low

A team of scientists at the Salk Institute for Biological Studies think they know how many-if not most-living organisms answer this question. They recently showed that when food supplies dwindle, mammals, fruitflies, or frogs probably activate the same ancient cell signaling pathway in order to conserve energy.

24 Apr 2008

Enzyme News and Research

Blocked brain enzyme shows potential as target for appetite control, weight loss and blood sugar management

Researchers find way to make tumor cells more sensitive to hyperthermia-enhanced radiation therapy

Clockwork PCR including sample prep

Geron Corporation awarded UK grant funding for human embryonic stem cell research

New chemicals shield 'genome guardian'

Discovery of tenovins could lead to cancer cure

Kidney disease substantially worsens in a fourth of African Americans despite therapy for hypertension

Study identifies new mechanism linking activation of key heart enzyme and oxidative stress

Breakthrough compound could lead to new class of antihypertensive drugs

Turning on cell-cell communication wipes out staph biofilms

Aspirin and other NSAIDs could lower the risk of breast cancer

Hydrogen sulphide may be involved in regulating blood pressure

Popular blood pressure drugs could hold the key to weight loss

Scientists discover way to increase metabolism for weight loss

Epigenetic research uncovers new targets for modification enzymes

Maitake mushrooms lead to breakthrough in protein research

Coffee protects some women against breast cancer

DNA vaccines may offer hope in multiple sclerosis

Pralatrexate for T-cell lymphoma

AMPK signaling helps explain how cell growth is inhibited when nutrients are low

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