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Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Like naked mole-rats (Heterocephalus gaber), blind mole-rats (of the genus Spalax) live underground in low-oxygen environments, are long-lived and resistant to cancer. A new study demonstrates just how cancer-resistant Spalax are, and suggests that the adaptations that help these rodents survive in low-oxygen environments also play a role in their longevity and cancer resistance.

4 Sep 2013

Study: Changes in expression of various isoforms might play role in cancer development

Spool-like proteins called histones play a crucial role in packaging the nearly seven feet of DNA found in most human cells. A new study shows that a group of histones that are thought to behave the same way actually are functionally distinct proteins.

4 Sep 2013

Baxter, Coherus Ink Biosimilar Collaboration Worth Up To $246M

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3 Sep 2013

Novel metabolic imaging method enhances prostate cancer diagnosis

Metabolic imaging with hyperpolarized pyruvate is a noninvasive and well-tolerated method for visualizing prostate tumors, US scientists have shown.

2 Sep 2013

Roche's Herceptin formulation wins EU approval for treatment of HER2-positive breast cancer

Halozyme Therapeutics, Inc. announced today that the European Commission has granted Roche European Union marketing authorization for the use of a time-saving subcutaneous formulation of Herceptin (trastuzumab) for the treatment of HER2-positive breast cancer.

2 Sep 2013

Researchers discover role played by epigenetic factors in senescence and age-related diseases

One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective measure by the body against run-away cell replication.

31 Aug 2013

Researchers study reproductive stage that remains most mysterious

Mississippi State University scientists are working to find out why some pregnancies are successful and others are not.

31 Aug 2013

Scientists identify protein that blocks death of high-risk acute lymphoblastic leukemia cells

St. Jude Children's Research Hospital scientists have identified a protein that certain high-risk acute lymphoblastic leukemia (ALL) cells need to survive and have used that knowledge to fashion a more effective method of killing tumor cells. The findings appear in the August 29 edition of the journal Blood.

30 Aug 2013

European Commission approves Stivarga tablets for treatment of patients with mCRC

Bayer HealthCare and Onyx Pharmaceuticals, Inc. (NASDAQ: ONXX) announced today that the European Commission has approved Stivarga® (regorafenib) tablets for the treatment of adult patients with metastatic colorectal cancer (mCRC).

30 Aug 2013

Findings establish gene as critical regulator of lung cancer tumor growth

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown that a well-known cancer-causing gene implicated in a number of malignancies plays a far more critical role in non-small cell lung cancer, the most common form of the disease, than previously thought.

30 Aug 2013

Findings lead to new drugs that block cancers from spreading to bone

When a cancer cell sloughs off the edge of a tumor in the breast, it faces a tough road to survive. The cell must not only remain physically intact as it rushes through blood vessels, but it also must find a new organ to lodge itself in, take in enough nutrients and oxygen to stay alive, and begin dividing, all while escaping notice by the body's immune system.

30 Aug 2013

Researchers receive $3M R01 award to test new approach to treating brain tumors

With a five-year, $3 million R01 award from the National Institutes of Health, through the National Cancer Institute, a team of researchers led by Gregory Fischer, PhD, assistant professor of mechanical engineering and robotics engineering at Worcester Polytechnic Institute and director of WPI's Automation and Interventional Medicine Laboratory, will test a new, minimally invasive approach to treating brain tumors that promises to accurately destroy malignant tissue while leaving surrounding tissue unaffected.

30 Aug 2013

Scientists identify enzyme mutation that occurs in castration-resistant prostate cancer

The mutation occurs in the androgen-synthesizing enzyme 3βHSD1 in castration-resistant prostate cancer (CRPC), according to research published online today in Cell. This mutation enables the tumor to make its own supply of androgens, a hormone that fuels the growth of the prostate cancer.

30 Aug 2013

Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

A prominent protein activated by inflammation is the key instigator that converts glioblastoma multiforme cells to their most aggressive, untreatable form and promotes resistance to radiation therapy, an international team lead by researchers at The University of Texas MD Anderson Cancer Center reported online today in the journal Cancer Cell.

30 Aug 2013

New joint research effort examines unique manifestation of breast cancer in Kenya

Breast cancer is a major health problem worldwide and the incidence of the disease is rising across Africa. A new joint research effort between the University of Notre Dame's Eck Institute for Global Health and Harper Cancer Research Institute and a Kenyan doctoral student from Moi University is examining the unique manifestation of breast cancer in Kenya.

30 Aug 2013

Reversing inflammation in fluid near brain's cortex may provide solution to Parkinson's disease

Reversing inflammation in the fluid surrounding the brain's cortex may provide a solution to the complex riddle of Parkinson's, according to researchers who have found a link between pro-inflammatory biomarkers and the severity of symptoms such as fatigue, depression and anxiety in patients with the chronic disease.

29 Aug 2013

Tumor News and Research

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Study: Changes in expression of various isoforms might play role in cancer development

Baxter, Coherus Ink Biosimilar Collaboration Worth Up To $246M

Novel metabolic imaging method enhances prostate cancer diagnosis

Roche's Herceptin formulation wins EU approval for treatment of HER2-positive breast cancer

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Researchers study reproductive stage that remains most mysterious

Scientists identify protein that blocks death of high-risk acute lymphoblastic leukemia cells

European Commission approves Stivarga tablets for treatment of patients with mCRC

Findings establish gene as critical regulator of lung cancer tumor growth

Findings lead to new drugs that block cancers from spreading to bone

Researchers receive $3M R01 award to test new approach to treating brain tumors

Scientists identify enzyme mutation that occurs in castration-resistant prostate cancer

Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

New joint research effort examines unique manifestation of breast cancer in Kenya

Reversing inflammation in fluid near brain's cortex may provide solution to Parkinson's disease

Tumor vessel density linked to mRCC treatment response

Findings support partial nephrectomy for T1b RCC

Inflammatory status upregulated in first-episode schizophrenia

Tumor Suppressor May Actually Drive Cancer Development

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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