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Scientists discover missing link in the way cells protect themselves against cancer

Cancer Research UK scientists have discovered a missing link in the way cells protect themselves against cancer, according to research published in Genes & Development.

5 Feb 2009

Novel gene may cause restless legs syndrome in a large family

In 2005, a woman who had trouble sleeping asked Siong-Chi Lin, M.D., for help. Dr. Lin, a sleep disorders specialist at the Mayo Clinic campus in Florida, diagnosed restless legs syndrome.

3 Feb 2009

Scientists unlock secrets of gene regulatory networks

A quartet of studies by researchers at the California Institute of Technology (Caltech) highlight a special feature on gene regulatory networks recently published in the Proceedings of the National Academy of Sciences ( PNAS ).

3 Feb 2009

Discovery fleshes out metabolism of key environmental and energy bacteria

An international collaboration of researchers has discovered a new enzyme in a species of bacteria with potential environmental cleanup and energy roles.

2 Feb 2009

New genetic clues on molecular evolution of Q fever pathogen

Scientists from the National Institute of Allergy and Infectious Diseases, Texas A&M Health Center, and the Virginia Bioinformatics Institute at Virginia Tech have uncovered genetic clues about why some strains of the pathogen Coxiella burnetii are more virulent than others.

2 Feb 2009

Single gene lets bacteria jump from host to host

All life - plants, animals, people - depends on peaceful coexistence with a swarm of microbial life that performs vital services from helping to convert food to energy to protection from disease.

2 Feb 2009

Discovery of new class of non-protein coding genes in mammals with key functions

A research team at the Broad Institute of Harvard and MIT and Beth Israel Deaconess Medical Center has uncovered a vast new class of previously unrecognized mammalian genes that do not encode proteins, but instead function as long RNA molecules.

2 Feb 2009

New technology analyzes breast cancer tumours to determine best treatment option

In a study published by Nature Biotechnology online on February 1, 2009, Mount Sinai Hospital researchers have unveiled a new technology tool that analyzes breast cancer tumours to determine a patient's best treatment options.

2 Feb 2009

You are what your parents ate!

According to Australian scientists we are what our parents ate - scientists at the Baker IDI Heart and Diabetes Institute say that very specific molecular events occur after the consumption of food high in glucose, causing chemical changes to our genetic controls.

2 Feb 2009

Research finds more than 100 gene variations linked with response to leukemia treatment

Scientists from St. Jude Children's Research Hospital and the Children's Oncology Group (COG) have discovered in children with acute lymphoblastic leukemia (ALL) scores of inherited genetic variations that clinicians might be able to use as guideposts for designing more effective chemotherapy for this cancer.

29 Jan 2009

Genetic variations associated with treatment response for acute lymphoblastic leukemia

Children with acute lymphoblastic leukemia with certain genetic variations can have a different response to anti-cancer treatment than other patients, according to a study in the January 28 issue of JAMA, the Journal of the American Medical Association.

29 Jan 2009

Rare amino acid helps establish how proteins evolve

Three billion years ago, a "new" amino acid was added to the alphabet of 20 that commonly make up proteins in organisms today.

29 Jan 2009

New understanding of genetic basis of psoriasis

Two international teams of researchers have made significant gains in understanding the genetic basis of psoriasis, a chronic skin condition that can be debilitating in some patients.

27 Jan 2009

New method captures microRNAs before they disappear

One of the tiniest entities in the human genome - are great escape artists.

27 Jan 2009

Scientists discover new class of small RNAs

Researchers at Cold Spring Harbor Laboratory (CSHL) announced today the discovery of a new class of small RNAs. At the same time, they reported that their discovery suggests the presence of a strikingly novel biochemical pathway for RNA processing in which these and possibly other small RNAs are produced.

27 Jan 2009

Compromised skin barrier function plays a role in the development of psoriasis

Researchers at the Genome Institute of Singapore (GIS) and the Anhui Medical University, China, have identified genes that play an important role in the development of psoriasis, a common chronic skin disease.

27 Jan 2009

Although our genetics differ significantly, we all look alike...

The genetic variation within a species can be significant, but very little of that variation results in clear differences in morphology or other phenotypes.

27 Jan 2009

Roche NimbleGen microarray technology enables highest-resolution map of human genome copy number variation

Roche NimbleGen's CGH microarray platform was used to generate the highest-resolution map of human genome copy number variation.

23 Jan 2009

Genetic interactions are the key to understanding complex traits

In recent years, genetic studies have uncovered hundreds of DNA variations linked to common diseases, such as cancer or diabetes, raising the prospect that scientists can gauge disease risk based on information in an individual's genome.

23 Jan 2009

More scientific evidence supporting Darwinian views of evolution

Studies at the University of Pennsylvania School of Medicine on brain electrical signaling offer a fresh perspective on vertebrate evolution, provide additional evidence supporting Darwinian views of evolution, and may also lead to more effective treatment of epileptic seizures in infants.

21 Jan 2009