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Idera Pharmaceuticals reports Phase 1 clinical trial results of IMO-8400

Idera Pharmaceuticals, Inc. announced results of a Phase 1 clinical trial of IMO-8400, a first-in-class antagonist of Toll-like Receptors 7, 8, and 9 being developed for potential applications in autoimmune and inflammatory diseases.

2 Jul 2013

SBRT treatment safe and effective for stage I NSCLC, study finds

Stereotactic body radiotherapy is considered the treatment of choice for early-stage non-small-cell lung cancer if patients are inoperable because of additional medical conditions.

2 Jul 2013

Genentech's Perjeta regimen gets FDA Priority Review for HER2-positive early stage breast cancer

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration has accepted the company's supplemental Biologics License Application for the use of a Perjeta (pertuzumab) regimen before surgery (neoadjuvant treatment) in people with HER2-positive early stage breast cancer.

2 Jul 2013

Nano and laser technology packed into small device tests antibiotic treatment in minutes

Researchers at EPFL have built a matchbox-sized device that can test for the presence of bacteria in a couple of minutes, instead of up to several weeks. A nano-lever vibrates in the presence of bacterial activity, while a laser reads the vibration and translates it into an electrical signal that can be easily read-the absence of a signal signifies the absence of bacteria.

1 Jul 2013

Study shows autophagy blockers play a role in treatment of non-small-cell lung cancer

New research from Rutgers Cancer Institute of New Jersey, Princeton University and other collaborators suggests that inactivation of an essential gene responsible for the cell survival process known as autophagy can suppress the growth of non-small-cell lung cancer tumors and render them more benign.

1 Jul 2013

Biomarker indicates which women are at risk for breast cancer recurrence after tamoxifen

A biomarker reflecting expression levels of two genes in tumor tissue may be able to predict which women treated for estrogen-receptor (ER)-positive breast cancer should receive a second estrogen-blocking medication after completing tamoxifen treatment.

30 Jun 2013

Physical activity and low calorie food may reduce risk of aggressive prostate cancer

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have published the first study on adherence to eight World Cancer Research Fund (WCRF) lifestyle recommendations and aggressive prostate cancer that shows a significantly decreased risk of highly aggressive prostate cancer associated with closer adherence to the recommendations.

30 Jun 2013

RPCI scientists assess safety and efficacy of immunotherapy approach to treat advanced melanoma

A new clinical research study at Roswell Park Cancer Institute (RPCI) will assess the safety and efficacy of a novel immunotherapy approach to treating advanced melanoma. Developed at RPCI by Roswell Park researchers, the investigational vaccine shows promise for treating tumors in patients with stage III/stage IV melanoma, and perhaps as a future therapy for other solid-tumor cancers as well.

30 Jun 2013

Researchers develop new drug delivery systems to treat cancer by blocking signaling receptor

A cardiac hormone signaling receptor abundantly expressed both in inflamed tissues and cancers appears to recruit stem cells that form the blood vessels needed to feed tumor growth, reports a new study by scientists at the University of South Florida Nanomedicine Research Center.

30 Jun 2013

Study: Pluripotent stem cell line-derived neurons survive and respond to cues in the primate brain

A team of researchers from Rush University, Yale University, the University of Colorado and the St. Kitts Biomedical Research Foundation transplanted human embryonic stem cells into primate laboratory animals modeled with Parkinson's disease and found "robust survival" of the cells after six weeks and indications that the cells were "well integrated" into the host animals.

29 Jun 2013

Olfactory ensheathing cells treatment improves neurological function in SCI patients: Study

A team of researchers in Poland who treated three of six paraplegics with spinal cord injury using transplanted olfactory ensheathing cells found that the three treated patients showed neurological improvement and no adverse effects while the three control patients who did not receive transplants saw no improvement.

29 Jun 2013

Case Comprehensive Cancer Center secures "outstanding" rating from NCI

The Case Comprehensive Cancer Center (CCCC) again demonstrated the compelling power of partnership in securing an overall rating of "outstanding" and a five-year renewal of its grant from the National Cancer Institute (NCI).

28 Jun 2013

km23-1 protein involved in spread of colon cancer may lead to new treatments for disease

Understanding how the protein km23-1 enables in the spread of colon cancer may lead to new treatments for the disease, according to researchers at Penn State College of Medicine.

28 Jun 2013

RUCDR Infinite Biologics receives $44.5 million Cooperative Agreement award from NIMH centre

RUCDR Infinite Biologics, the world's largest university-based biorepository, received a $44.5 million Cooperative Agreement award from the National Institute of Mental Health earlier this month to support its NIMH Center for Collaborative Genomics Research on Mental Disorders, which provides services to NIMH-funded scientists engaged in genomic research on mental disorders.

28 Jun 2013

Decorin protein in blood inhibits tumor progression, say researchers

Researchers from Thomas Jefferson University's Kimmel Cancer Center have discovered that decorin, a naturally occurring protein that circulates in the blood, acts as a potent inhibitor of tumor growth modulating the tumor microenvironment.

28 Jun 2013

Rural women with breast cancer less likely to receive radiation therapy after lumpectomy

Rural women with breast cancer are less likely than their urban counterparts to receive recommended radiation therapy after having a lumpectomy, a breast-sparing surgery that removes only tumors and surrounding tissue, a study by Mayo Clinic and others found.

28 Jun 2013

Computer simulation for predicting effectiveness of combination therapies for colon tumors

Scientist at Charité - Universitätsmedizin Berlin have used a computer simulation for predicting the effectiveness of various combination therapies for colon tumors. The study has been published in the current issue of the professional journal Molecular Systems Biology*.

28 Jun 2013

Weekend reading: Chemo revolution, Lyme disease confusion and the residency mismatch

Because I've lived so long with anxiety, there were lots of things I figured I'd never, ever do -; having children was one of them. In fact, in my 20s, before I'd managed to stumble on the combination of drugs and exercise that allows me to be as sane as I can expect to be, I was so sure I'd never give birth that I got a tattoo of a giant koi fish extending from one end of my abdomen to the other. ... I found myself in a very ironic situation: my decision to have a child was the result of a sense of stability I enjoyed due to taking an array of anti-anxiety medications that I would be strongly advised by most doctors to stop taking now that I was pregnant (Alissa Nutting, 6/23).

28 Jun 2013

Stanford researchers take new step in deciphering of histone code

A chemical code scrawled on histones - the protein husks that coat DNA in every animal or plant cell - determines which genes in that cell are turned on and which are turned off.

28 Jun 2013

Patients' medical follow-up after melanoma diagnosis should be lifelong, says study author

Recurrence of melanoma skin cancer 10 or more years after initial treatment is more common than previously thought, occurring in more than one in 20 patients. However, according to a new study, these patients tend to live longer after their cancer returns than patients whose melanoma recurs in the first three years.

28 Jun 2013

Tumor News and Research

Idera Pharmaceuticals reports Phase 1 clinical trial results of IMO-8400

SBRT treatment safe and effective for stage I NSCLC, study finds

Genentech's Perjeta regimen gets FDA Priority Review for HER2-positive early stage breast cancer

Nano and laser technology packed into small device tests antibiotic treatment in minutes

Study shows autophagy blockers play a role in treatment of non-small-cell lung cancer

Biomarker indicates which women are at risk for breast cancer recurrence after tamoxifen

Physical activity and low calorie food may reduce risk of aggressive prostate cancer

RPCI scientists assess safety and efficacy of immunotherapy approach to treat advanced melanoma

Researchers develop new drug delivery systems to treat cancer by blocking signaling receptor

Study: Pluripotent stem cell line-derived neurons survive and respond to cues in the primate brain

Olfactory ensheathing cells treatment improves neurological function in SCI patients: Study

Case Comprehensive Cancer Center secures "outstanding" rating from NCI

km23-1 protein involved in spread of colon cancer may lead to new treatments for disease

RUCDR Infinite Biologics receives $44.5 million Cooperative Agreement award from NIMH centre

Decorin protein in blood inhibits tumor progression, say researchers

Rural women with breast cancer less likely to receive radiation therapy after lumpectomy

Computer simulation for predicting effectiveness of combination therapies for colon tumors

Weekend reading: Chemo revolution, Lyme disease confusion and the residency mismatch

Stanford researchers take new step in deciphering of histone code

Patients' medical follow-up after melanoma diagnosis should be lifelong, says study author

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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