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Isaiah J. Fidler earns 2013 American Cancer Society Medal of Honor for Basic Research

When Isaiah J. Fidler, D.V.M., Ph.D., left his veterinary surgical practice to pursue a doctorate that would allow him to study and combat the lethal spread of cancer to other organs, he got lots of advice. The common message: Don't go there.

30 May 2013

Ruthenium complexes could pave way for cancer treatments, say UT Arlington researchers

A team of UT Arlington researchers has identified two ruthenium-based complexes they believe could pave the way for treatments that control cancer cell growth more effectively and are less toxic for patients than current chemotherapies.

30 May 2013

Scientists report that human scabs have become model for advanced wound dressing material

Human scabs have become the model for development of an advanced wound dressing material that shows promise for speeding the healing process, scientists are reporting. Their study appears in the journal ACS Applied Materials & Interfaces.

30 May 2013

Radiotherapy: First choice treatment for low-grade glioma

In a large, international, randomized trial, initial radiotherapy was compared to temozolomide chemotherapy. A statistically significant difference between the two treatment strategies was not observed for progression-free survival, although radiotherapy was numerically favored. However, molecular tumor characterization may allow the treatment approach to be personalized and one or the other treatment modality to be selected.

30 May 2013

Tafinlar, Mekinist get FDA approval to treat patients with advanced melanoma

The U.S. Food and Drug Administration today approved two new drugs, Tafinlar (dabrafenib) and Mekinist (trametinib), for patients with advanced (metastatic) or unresectable (cannot be removed by surgery) melanoma, the most dangerous type of skin cancer.

30 May 2013

Spherical nanoparticles transform into netlike structures at site of cancer

Scientists at the University of California, San Diego, have designed tiny spherical particles to float easily through the bloodstream after injection, then assemble into a durable scaffold within diseased tissue. An enzyme produced by a specific type of tumor can trigger the transformation of the spheres into netlike structures that accumulate at the site of a cancer, the team reports in the journal Advanced Materials this week.

29 May 2013

Scientists identify role of GSK-3 alpha protein in promoting oncogenic KRAS function

While the mutated KRAS oncogene is associated with many cancers, it has not yet been successfully targeted by a therapeutic agent. Scientists are trying to find another way to target the gene by blocking signals from another protein downstream.

29 May 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

New approach to battle prostate cancer

Dr. Jung-Mo Ahn, associate professor of chemistry at The University of Texas at Dallas, has designed and synthesized a novel small molecule that might become a large weapon in the fight against prostate cancer.

29 May 2013

UT Southwestern researchers develop new class of drugs for prostate cancer

A new study on prostate cancer describes a novel class of drugs developed by UT Southwestern Medical Center researchers that interrupts critical signaling needed for prostate cancer cells to grow.

29 May 2013

Sorrento Therapeutics, IGDRASOL announce publication of clinical data for Cynviloq and gemcitabine

Sorrento Therapeutics, Inc. and IGDRASOL announced today that clinical data for CynviloqTM, a non-biologic nanoparticle formulation of paclitaxel, plus gemcitabine was published for the upcoming Annual Meeting of the American Society of Clinical Oncology.

28 May 2013

St James's Institute of Oncology orders two Versa HD systems to improve patient care

St James's Institute of Oncology, a leading radiotherapy center in the UK, recently ordered two Versa HD™ systems, an advanced linear accelerator designed to improve patient care and treat a wide range of tumors throughout the body.

From Elekta 28 May 2013

GATA-3 protein plays an important role in mammalian immune response

The protein GATA-3 plays an important role in mammalian immune response, but its overall function in cell development and cancer formation is not well understood. In an effort to further define the importance of GATA-3, researchers at the University of North Carolina have traced how the protein performs important functions in CD8+T-cell type of the immune system.

27 May 2013

Researchers develop multicolor fluorescence labeling method to identify tumor specific miRNAs

In recent years, microRNAs and other non-coding RNAs are small molecules that help control the expression of specific proteins. In recent years they have emerged as disease biomarkers.

27 May 2013

Scientists report new way of tackling cancer and predicting tumor virulence

A new way of tackling cancer and predicting tumor virulence are has been reported by a team of scientists from the Institut Albert Bonniot de Grenoble including researchers from CNRS, Inserm and Université Joseph Fourier, in collaboration with clinical physicians and anatomopathologists from the CHU de Grenoble, with the support of the Institut National du Cancer, the Ligue Nationale Contre le Cancer and the Fondation ARC pour la Recherche sur le Cancer.

26 May 2013

Study suggests possible way to halt cancer development in premalignant cells

Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant-cells on the cusp between normalcy and cancers-which may lead to new methods of stopping tumors.

24 May 2013

New research identifies mechanism to make cancer cells respond to chemotherapy

Breast cancer characterized as "triple negative" carries a poor prognosis, with limited treatment options. In some cases, chemotherapy doesn't kill the cancer cells the way it's supposed to. New research from Western University explains why some cancer cells don't respond to chemotherapy, and identifies a mechanism to rectify that.

24 May 2013

New, improved drugs can boost body's natural flu killer system

A known difficulty in fighting influenza (flu) is the ability of the flu viruses to mutate and thus evade various medications that were previously found to be effective. Researchers at the Hebrew University of Jerusalem have shown recently that another, more promising, approach is to focus on improving drugs that boost the body's natural flu killer system.

24 May 2013

Some aggressive forms of prostate cancer have similar genetic origins

Mayo Clinic researchers have used next generation genomic analysis to determine that some of the more aggressive prostate cancer tumors have similar genetic origins, which may help in predicting cancer progression. The findings appear online today in the journal Cancer Research.

24 May 2013

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs before it's dissolved, researchers reported in an early online publication at Nature.

24 May 2013

Tumor News and Research

Isaiah J. Fidler earns 2013 American Cancer Society Medal of Honor for Basic Research

Ruthenium complexes could pave way for cancer treatments, say UT Arlington researchers

Scientists report that human scabs have become model for advanced wound dressing material

Radiotherapy: First choice treatment for low-grade glioma

Tafinlar, Mekinist get FDA approval to treat patients with advanced melanoma

Spherical nanoparticles transform into netlike structures at site of cancer

Scientists identify role of GSK-3 alpha protein in promoting oncogenic KRAS function

Transplantation of human stem cells improves muscle function in rats used to model ALS

New approach to battle prostate cancer

UT Southwestern researchers develop new class of drugs for prostate cancer

Sorrento Therapeutics, IGDRASOL announce publication of clinical data for Cynviloq and gemcitabine

St James's Institute of Oncology orders two Versa HD systems to improve patient care

GATA-3 protein plays an important role in mammalian immune response

Researchers develop multicolor fluorescence labeling method to identify tumor specific miRNAs

Scientists report new way of tackling cancer and predicting tumor virulence

Study suggests possible way to halt cancer development in premalignant cells

New research identifies mechanism to make cancer cells respond to chemotherapy

New, improved drugs can boost body's natural flu killer system

Some aggressive forms of prostate cancer have similar genetic origins

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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