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Study shows close link between cytokine interleukin-1ß and obesity-promoted colon cancer

A new study describes the mechanistic relationship between the cytokine interleukin-1β, (IL-1β) and obesity, showing that when IL-1β levels are increased in obesity, IL-1 receptor signaling activates multiple pathways leading to colon cancer.

18 Oct 2018

Patients once thought incurable can benefit from high-dose radiation therapy

In the first randomized, phase II clinical trial of its kind, researchers have shown that an aggressive form of high-precision radiation therapy can greatly increase how long oligometastatic patients live and doubles how long they live without cancer.

17 Oct 2018

New blood test for pediatric brain tumor patients offers safer approach than surgical biopsies

A new blood test for children with brain tumors offers a safer approach than surgical biopsies and may allow doctors to measure the effectiveness of treatment even before changes are identified on scans, according to research led by UCSF Benioff Children’s Hospitals and Children’s National Health System.

16 Oct 2018

Study pinpoints new marker that can predict Crohn’s disease subtype

Crohn's disease, a chronic inflammatory condition of the intestinal tract, has emerged as a global disease, with rates steadily increasing over the last 50 years.

16 Oct 2018

Modeling Non-Numerical Data in Systems Biology

An interview with Dr. Eshan Mitra, discussing the importance of computer models in biology and the development of a more accurate model of the RAF phosphorylation pathway.

15 Oct 2018

Study unravels how cancer stem cells use normal genes in abnormal ways

CDK1 is a "normal" protein - its presence drives cells through the cycle of replication. And MHC Class I molecules are "normal" as well - they present bits of proteins on the surfaces of cells for examination by the immune system.

15 Oct 2018

Obesity associated with higher risk of early-onset colorectal cancer

Women who are overweight or obese have up to twice the risk of developing colorectal cancer before age 50 as women who have what is considered a normal body mass index (BMI), according to new research led by Washington University School of Medicine in St. Louis.

12 Oct 2018

Inflammatory proteins in the colon increase in parallel with increasing weight, study shows

Studies in mice have demonstrated that obesity-induced inflammation contributes to the risk of colorectal cancer, but evidence in humans has been scarce.

11 Oct 2018

International audit of colorectal surgeries provides highly realistic reflection of current practices

The European Society of Coloproctology has undertaken a major international audit of colorectal operations to understand which are most widely used techniques across the world, which appear to be associated with the best outcomes and where further research needs to be undertaken.

10 Oct 2018

Study suggests novel approach to treating adults with autism spectrum disorder

A team of scientists at Florida Atlantic University has uncovered a brain-signaling pathway that can be pharmacologically manipulated in genetically engineered mice to reverse an autism-related pathway.

8 Oct 2018

Frequent surveillance imaging not associated with improved overall postoperative survival

Cancer treatment continues to improve for many types of cancer, leading to increased life expectancy for many survivors.

5 Oct 2018

Aspirin shown to prevent the spread of cancer

New research by Cardiff University has demonstrated a role for Aspirin in the treatment of bowel, prostate and breast cancer.

1 Oct 2018

Promising vaccine may provide new treatment option for patients with HER2-positive cancers

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3.

30 Sep 2018

New European School of Coloproctology launched by ESCP

The European Society of Coloproctology’s (ESCP) Education Committee has launched a new training school to help surgeons continue their professional education and development in the latest techniques of their field.

28 Sep 2018

New study assessing SSI incidence paves way for future research into nursing outcomes

A recent study assessing the relationship between nursing specialty certification rates and surgical site infections provides an innovative option for future research exploring relationships between nursing and hospital procedures and medical and/or surgical adverse events.

26 Sep 2018

Hybrid operating room enables faster diagnosis, treatment of patients with lung cancer

Representing a paradigm shift in thoracic surgery, the hybrid operating room combines three techniques into a single appointment eliminating multiple clinical visits for improved patient experience and outcomes.

25 Sep 2018

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

The SR101 N-(3-[18F]Fluoropropyl) sulfonamide ([18F]SRF101) is a Sulforhodamine 101 derivative that was previously synthesized by our group.

25 Sep 2018

Researchers identify new genetic disorder in a human patient

Researchers from Michigan State University College of Human Medicine and physicians from Spectrum Health have identified for the first time in a human patient a genetic disorder only previously described in animal models.

21 Sep 2018

Study: Annual wellness visits improve delivery of preventive services in elderly population

new Harvey L. Neiman Health Policy Institute study assesses the effect of receiving an Annual Wellness Visit between 2011 and 2013 on the annual rate of eight preventive services recommended for the Medicare population following the AWV.