Myocardial Infarction News and Research

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Scientists take major step towards treatment for heart attack

A team of scientists at Karolinska Institutet and Harvard University has taken a major step towards treatment for heart attack, by instructing the injured heart in mice to heal by expressing a factor that triggers cardiovascular regeneration driven by native heart stem cells.

10 Sep 2013

Biomarker strategy in suspected ACS patients has potential to change clinical practice

An emergency department strategy that uses two biomarkers to triage patients with suspected acute coronary syndrome (ACS) can increase the rate of early, safe hospital discharge, according to results of the Biomarkers in Cardiology 8 (BIC-8) trial.

5 Sep 2013

Preventive PCI for patients with ST elevation myocardial infarction results in better outcomes

Heart attack patients with ST elevation who undergo a preventive procedure to unblock additional coronary arteries have significantly better outcomes than those whose treatment is confined to the culprit blockage only, according to the results of the Preventive Angioplasty in Myocardial Infarction (PRAMI) Trial

5 Sep 2013

TASTE trial questions the usefulness of thrombus aspiration after heart attack

Aspiration of the blood clot or "thrombus" that causes a heart attack before re-opening a patient's artery with a balloon catheter does not improve survival compared to performing balloon dilation and stenting alone according to the results of the Thrombus Aspiration in ST- Elevation myocardial infarction in Scandinavia (TASTE) trial.

5 Sep 2013

Multiple risk factors eliminate impact of AF on stroke risk, but more research is needed

Dr Benn Christiansen said: "We know that atrial fibrillation increases the risk of ischemic stroke. And in patients with atrial fibrillation or previous ischemic stroke, the risk of stroke increases with the number of risk factors.

5 Sep 2013

Golgi apparatus: New target for treatment of acute cerebral infarction

Expression of soluble CD40L has been shown to increase sig-nificantly in conditions such as stroke, myocardial infarction, unstable angina, high cholesterol, or other cardiovascular events. 95% of the circulating CD40L exists in activated platelets.

5 Sep 2013

Secondary prevention drugs produce decline in stroke risk after AMI in diabetic patients

The findings were presented at the ESC Congress today by Ms Stina Jakobsson from Sweden. They reveal that reperfusion therapy and secondary prevention drugs produced the decline and brought stroke risk after AMI closer to that of non-diabetics.

5 Sep 2013

Indicators of poor preoperative health predict risk of major medical complications

For older adults undergoing surgery for spinal stenosis, some simple indicators of poor preoperative health predict a high risk of major medical complications, reports a study in the September 1 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

4 Sep 2013

Findings challenge existing paradigms for prolonging antiplatelet therapy after PCI

Lead study investigators from Icahn School of Medicine at Mount Sinai presented their Patterns of Non-Adherence to Anti-Platelet Regimens in Stented Patients (PARIS) study findings at the ESC Congress 2013 in Amsterdam organized by the European Society of Cardiology.

3 Sep 2013

Study assesses relationship between BMI and CV events in hypertensive patients with diabetes

Low BMI is a risk factor for CVD in hypertensive patients with diabetes, according to research presented at the ESC Congress today by Dr Takanori Nagahiro from Japan. The findings provide evidence for an obesity paradox in hypertensive patients with glucose intolerance.

3 Sep 2013

Study finds reduction in incidence of STEMI after smoking ban implemented in Switzerland

Second-hand smoke increases the risk of coronary artery disease and acute myocardial infarction. For this reason, health policies aimed at reducing tobacco consumption and public smoke exposure are strongly recommended.

2 Sep 2013

Women are 25% less likely to die post TAVI than men, says doctor

Dr Sherif said: "Earlier studies on the impact of gender on outcome after transcatheter aortic valve implantation (TAVI) have had conflicting results. A Canadian study reported in 641 consecutive patients that female sex is associated with a better long-term and short-term survival after TAVI.1 An Italian study of 305 high risk patients found no gender differences in composite safety and efficacy endpoints at 30 days and one year after TAVI."2

2 Sep 2013

Low temperature triggers acute myocardial infarction

Professor Claeys said: "Air pollution and temperature changes are the most frequently reported environmental triggers for acute myocardial infarction (AMI). Epidemiologic studies have focused mainly on one environmental condition, but most environmental triggers are related to each other and may attenuate or reinforce the triggering effect of a single environmental factor."

2 Sep 2013

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Patients with type 2 diabetes and high cardiovascular risk due to recent acute coronary syndromes had similar rates of cardiovascular events when treated with the anti-diabetic agent alogliptin compared to placebo according to results of the Examination of Cardiovascular Outcomes with Alogliptin versus Standard of Care trial presented at the European Society of Cardiology Congress.

2 Sep 2013

Use of anticoagulant does not reduce ischemic events among patients undergoing PCI

Use of the novel anticoagulant otamixaban did not reduce ischemic events compared with unfractionated heparin plus eptifibatide but increased bleeding among patients with non-ST-segment elevation acute coronary syndromes undergoing a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), according to a study published by JAMA.

2 Sep 2013

Pre-treatment with prasugrel increases risk of bleeding without reducing risk of ischemic events

In patients with non-ST-elevation acute coronary syndrome (NSTE- ACS), pre-treatment with the P2Y12 antagonist prasugrel prior to catheterization, significantly increases the risk of life-threatening bleeding without reducing the risk of major ischemic events, according to the results of the ACCOAST (A Comparison of Prasugrel at PCI or Time of Diagnosis of Non-ST Elevation Myocardial Infarction) trial.

2 Sep 2013

CAD patients with very low LDL-C levels benefit from statin treatment

Dr Nakano said: "Many randomised clinical trials, such as Treating to New Targets (TNT) and PROVE IT-TIMI, have shown that aggressive cholesterol lowering with statins improves clinical outcomes in patients with CAD and high LDL-C levels.1,2 But until now it was not known whether aggressive lipid lowering with statins would also benefit CAD patients with very low LDL-C levels."

2 Sep 2013

High waist circumference associated with greatest risk of death in heart attack survivors

Having a big belly increases the risk of death in heart attack survivors, according to research presented at ESC Congress 2013 by Professor Tabassome Simon and Professor Nicolas Danchin from France.

2 Sep 2013

Deaths from cardiovascular disease higher in winter and lower in summer, says doctor

Dr Marques-Vidal said: "Deaths from cardiovascular disease are higher in winter and lower in summer. We decided to conduct a large scale study to see whether cardiovascular risk factors have a seasonal pattern which could explain the seasonality in deaths."

2 Sep 2013

Loyola's success in implementing standard of care for heart attack patients recognized by AHA

Loyola University Medical Center has received the American Heart Association's Mission: Lifeline Silver Receiving Quality Achievement Award, which recognizes Loyola's commitment and success in implementing an exceptional standard of care for heart attack patients.

29 Aug 2013

Myocardial Infarction News and Research

Scientists take major step towards treatment for heart attack

Biomarker strategy in suspected ACS patients has potential to change clinical practice

Preventive PCI for patients with ST elevation myocardial infarction results in better outcomes

TASTE trial questions the usefulness of thrombus aspiration after heart attack

Multiple risk factors eliminate impact of AF on stroke risk, but more research is needed

Golgi apparatus: New target for treatment of acute cerebral infarction

Secondary prevention drugs produce decline in stroke risk after AMI in diabetic patients

Indicators of poor preoperative health predict risk of major medical complications

Findings challenge existing paradigms for prolonging antiplatelet therapy after PCI

Study assesses relationship between BMI and CV events in hypertensive patients with diabetes

Study finds reduction in incidence of STEMI after smoking ban implemented in Switzerland

Women are 25% less likely to die post TAVI than men, says doctor

Low temperature triggers acute myocardial infarction

Anti-diabetic drug alogliptin meets primary endpoint in EXAMINE trial

Use of anticoagulant does not reduce ischemic events among patients undergoing PCI

Pre-treatment with prasugrel increases risk of bleeding without reducing risk of ischemic events

CAD patients with very low LDL-C levels benefit from statin treatment

High waist circumference associated with greatest risk of death in heart attack survivors

Deaths from cardiovascular disease higher in winter and lower in summer, says doctor

Loyola's success in implementing standard of care for heart attack patients recognized by AHA

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