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Gene mutation helps protect against malaria

New research suggests that not everyone who is bitten by a malaria-infected mosquito develops life threatening health problems according to scientists at the University of Toronto.

21 Apr 2008

Can IT fuel the race to the $1,000 human genome?

Ever wonder if you have a genetic disposition to a certain disease, or why a medicine works for your friend, but not for you?

21 Apr 2008

Mature B cells reprogrammed to stem-cell-like state

Fully mature, differentiated B cells can be reprogrammed to an embryonic-stem-cell-like state, without the use of an egg, according to a study published in the April 18 issue of Cell.

18 Apr 2008

Interaction networks: the new path to drug discovery

Although the pharmaceutical industry has dedicated enormous research efforts over the last 50 years to identify new targets and develop new active ingredients, these efforts have met with limited success.

17 Apr 2008

Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency

Fully mature, differentiated B cells can be reprogrammed to an embryonic-stem-cell-like state, without the use of an egg according to a study published in the April 18 issue of Cell.

17 Apr 2008

Breakthrough in migraine genetics

In a new study, published in the American Journal of Human Genetics, researchers were able for the first time to convincingly demonstrate a genomic locus to be linked to migraine susceptibility in two diverse populations.

17 Apr 2008

Discovery of critical detail of cellular defense against genetic mistakes

Researchers are closing in on a completed diagram of how human cells protect themselves against constant genetic mistakes that contribute to most diseases, according to a study to be published in the April 18 edition of the journal Cell.

17 Apr 2008

Global Alliance for Pharmacogenomics

Leaders at the National Institutes of Health and the Center for Genomic Medicine in Japan have signed a letter of intent creating a Global Alliance for Pharmacogenomics.

15 Apr 2008

Targeted therapy combo overcomes treatment resistance in liver cancer

Researchers at the University of Pennsylvania School of Medicine and Abramson Cancer Center reported at the annual meeting of the American Association for Cancer Research that combining two targeted therapies overcomes treatment resistance in liver cancer cell lines.

13 Apr 2008

New strategy rapidly describes outbreak strains with next-generation DNA sequencing

In the event of an outbreak or a bioterrorist attack, rapid identification of the genetic changes responsible for virulence or drug resistance is essential to mounting an effective response.

11 Apr 2008

Blood vessels: The pied piper for growing nerve cells

Researchers at Johns Hopkins have discovered that blood vessels in the head can guide growing facial nerve cells with blood pressure controlling proteins.

11 Apr 2008

Biomarkers may reduce the need for biopsies and personalize transplant patient care

Data presented at the 28th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) suggest the potential of a significant impact of using biomarkers to reduce the need for biopsies and personalize transplant patient care.

11 Apr 2008