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Brain scientist shedding light on learning, memory

Neurons spoke to Dr. Joe Z. Tsien when he was a sophomore college student searching for some meaningful extracurricular activity.

28 Mar 2008

Beetle genome opens the door to developmental research

The whole DNA sequence of the red flour beetle, familiar to many as an unwelcome visitor to the kitchen flour jar, has been published in Nature .

28 Mar 2008

Study examines association between type of genetic characteristics and cancer

Persons with a certain type of homozygosity (having two identical copies of the same gene, one inherited from each parent), may have a greater predisposition to cancer, according to a study in the March 26 issue of JAMA.

26 Mar 2008

New method for rapid screening large numbers of antigens

A team of Washington State University scientists has devised a method that could lead to the development of vaccines against some of the most troubling infectious diseases we face diseases that have so far been difficult or impossible to vaccinate against.

26 Mar 2008

A new form of inherited risk of cancer found

Like the subtext of a novel, the human genome sequence harbors more information than appears just in its "letters" of A, C, T and G. Since DNA is a data-packed molecule passed from generation to generation, comparing genome sequences among individuals also holds clues to ancestry.

26 Mar 2008

Microbes in the guts of carpenter ants could lead to better drugs

Scientists have discovered two key proteins that guide one of the two groups of pathogenic bacteria to make their hardy outer shells -- their defense against the world.

26 Mar 2008

Toward the ethical treatment of whole genome research participants

Recent technological developments have made it possible for scientists to sequence an entire human genome, but these advances may be a mixed blessing.

25 Mar 2008

New software finds 11 genetic variations to type 2 diabetes

Mathematicians at Michigan Technological University have developed powerful new tools for winnowing out the genes behind some of humanity's most intractable diseases.

25 Mar 2008

Researchers reveal hidden properties of an on-off switch that governs cell growth

Investigators at the Duke Institute for Genome Sciences and Policy have revealed the hidden properties of an on-off switch that governs cell growth.

25 Mar 2008

New genetic clue to Parkinson's disease

Researchers at Rhode Island Hospital and The Warren Alpert Medical School of Brown University have discovered a gene that could hold the key to developing new treatments for Parkinson's disease – a progressive and often debilitating movement disorder that affects as many as one million Americans.

24 Mar 2008

Toxic organophosphates appear to contribute to motor neuron disease

Motor neuron disease is a rare, devastating illness in which nerve cells that carry brain signals to muscles gradually deteriorate.

24 Mar 2008

Deadly genetic disease prevented before birth in zebrafish with genetic patch

By injecting a customized "genetic patch" into early stage fish embryos, researchers at Washington University School of Medicine in St. Louis were able to correct a genetic mutation so the embryos developed normally.

24 Mar 2008

Disruption of the Contactin 4 gene on chromosome 3 may be linked to autism spectrum disorder

Eli Hatchwell, M.D., Ph.D., Associate Professor of Pathology at Stony Brook University Medical Center, and colleagues have found that a disruption of the Contactin 4 gene on chromosome 3 may be linked to autism spectrum disorder (ASD).

20 Mar 2008

New method to determine the “selective signature” of a gene

Scientists at MIT have come up with a mathematical approach for analyzing a protein simultaneously in a set of ecologically distinct species to identify occurrences of natural selection in an organism's evolution.

19 Mar 2008

$Variants of the gene LRP5 associated with increased risk of bone fractures, low bone mineral density$

Variants of the gene LRP5 associated with increased risk of bone fractures, low bone mineral density

Results from a large study indicate that variants of the gene LRP5 are associated with a significant increase in the risk of fractures, by up to 20 percent, and lower levels of bone mineral density in the spine and hip, according to a study in the March 19 issue of JAMA, a theme issue on Genetics and Genomics.

19 Mar 2008

Silencing gene in tobacco plants reduces harmful carcinogens

In large-scale field trials, scientists from North Carolina State University have shown that silencing a specific gene in burley tobacco plants significantly reduces harmful carcinogens in cured tobacco leaves.

19 Mar 2008

At home genomic tests for disease risk may be premature

The recent marketing of "at home" genomic tests for disease risk may be premature, according to Dr. Kenneth Offit, MD, MPH, Chief of the Clinical Genetics Service at Memorial Sloan-Kettering Cancer Center (MSKCC).

19 Mar 2008

Zebrafish enables cell regeneration studies to help understand, treat human disease

One aquarium fish's uncanny ability to regenerate essentially any cell type has given scientists a way to mimic cell loss that occurs in diseases such as Parkinson's and diabetes then watch how the fish make more of them.

18 Mar 2008

Surprising discovery from first large-scale analysis of biodiversity and biogeography of viruses

Viruses and bacterial viruses (known as phages) are among the most abundant life forms on the planet.

18 Mar 2008

Scientists identify potential therapy targets for schistosomiasis

A research team supported by the National Institutes of Health (NIH) Roadmap and the National Institute of Allergy and Infectious Diseases (NIAID) has identified chemical compounds that hold promise as potential therapies for schistosomiasis, a parasitic disease that afflicts more than 200 million people worldwide.

18 Mar 2008