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Discovery of multiple genes linked to systemic lupus erythematosus

A landmark genetic study has identified multiple genes linked to systemic lupus erythematosus (SLE), or lupus, a debilitating autoimmune disease that affects an estimated 1.4 million Americans.

21 Jan 2008

Genome scan shows Polynesians and Micronesians have almost no genetic relation to Melanesians

The origins and current genetic relationships of Pacific Islanders have generated interest and controversy for many decades.

21 Jan 2008

Genetic diversity of European Americans and disease gene mapping

Labels such as "European American", "white", or "Caucasian" are often viewed as representing a homogeneous category in gene mapping studies and census reports, but each of these labels actually groups together multiple populations, which have diverse origins due to the complex history of European immigration to the United States.

21 Jan 2008

Previously unknown Merkel cell polyomavirus linked to deadly skin cancer

A new strategy to hunt for human viruses described in this week's issue of the journal Science by the husband-and-wife team who found the cause of Kaposi's sarcoma has revealed a previously unknown virus strongly associated with another rare but deadly skin cancer called Merkel cell carcinoma.

18 Jan 2008

Previously unknown chromosomal abnormalities play substantial role in autism

Genome-wide scans of families affected by autism spectrum disorder (ASD) have revealed new evidence that previously unknown chromosomal abnormalities have a substantial role in the prevalent developmental disorder, according to a report published online Jan. 17th in the American Journal of Human Genetics, a publication of Cell Press.

18 Jan 2008

Scientists focus on Epstein-Barr virus

Epstein-Barr virus (EBV) is a human-pathogenic virus which belongs to the herpes virus family.

18 Jan 2008

New technique could dramatically lower costs of DNA sequencing

Using computer simulations, researchers at the University of Illinois have demonstrated a strategy for sequencing DNA by driving the molecule back and forth through a nanopore capacitor in a semiconductor chip.

16 Jan 2008

Gender differences in liver cancer

A fundamental difference in the way males and females respond to chronic liver disease at the genetic level helps explain why men are more prone to liver cancer, according to MIT researchers.

16 Jan 2008

Genetic differences may explain response to multiple sclerosis treatment

By comparing the DNA of patients with multiple sclerosis whose symptoms are reduced by interferon beta therapy to the DNA of those who continue to experience relapses, researchers may have identified important genetic differences between the two, according to an article posted online that will appear in the March 2008 print issue of Archives of Neurology.

16 Jan 2008

Genetic differences may help explain response to multiple sclerosis treatment

15 Jan 2008

6,000 genes help determine body weight

Reporting in the online journal BMC Genetics, researchers from the Monell Center have for the first time attempted to count the number of genes that contribute to obesity and body weight.

15 Jan 2008

Discovery of seven new genes that influence blood cholesterol levels

An international study of 20,000 people found seven new genes that influence blood cholesterol levels, a major factor in heart disease, and confirmed 11 other genes previously thought to influence cholesterol.

15 Jan 2008

Researchers associate six new genetic variants with heart disease risk factor

Using new techniques for rapidly scanning the human genome, researchers have associated levels of cholesterol and triglycerides, two fats in the blood, to 18 genetic variants, six of which represent new DNA regions never before associated with the traits.

15 Jan 2008

New genetic variations associated with lipid levels, risk for coronary artery disease

Environmental and genetic factors influence a person's blood fat, or lipid levels, important risk factors for coronary artery disease (CAD). While there is some understanding of the environmental contribution, the role of genetics has been less defined.

14 Jan 2008

Study suggests link between genetic basis of height and arthritis

In studies involving more than 35,000 people and a survey across the entire human genome, an international team supported in part by the National Institutes of Health (NIH) has found evidence that common genetic variants recently linked to osteoarthritis may also play a minor role in human height.

14 Jan 2008

Dissecting the genetic components of adaptation of E. coli to the mouse gut

New insights into the evolutionary mechanisms that facilitate the remarkably fast adaptation of intestinal bacteria within their natural environment are provided in the January issue of PLoS Genetics by researchers from INSERM and INRA at University Paris Descartes.

14 Jan 2008