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Paracentesis performed in an outpatient setting by gastrointestinal endoscopy assistants is safe

Large-volume paracentesis is a treatment used to remove excess fluid in the abdominal cavity resulting from such conditions as cirrhosis of the liver or cardiac failure. It is normally performed as an inpatient procedure due to possible complications, which may include infection, bleeding, and bowel perforation.

18 Aug 2004

Organ transplant recipients infected with West Nile virus develop more severe neurological illness

West Nile virus is an infection which in the last three years has had a significant impact in the United States. The virus is spread from birds to humans via mosquito bites. Symptoms include headache, fever and disorientation, and the disease can cause serious illness in a small percentage of infected people.

18 Aug 2004

New imaging technique may help cystic fibrosis sufferers

Now, Jefferson Lab scientists have used their expertise to build a small animal medical imager that's helping researchers develop a new gene therapy technique for cystic fibrosis.

15 Aug 2004

British team and NASA plan to take stem cells into space

The $US1 million project aims to explore ways to protect astronauts from space radiation in preparation for a manned mission to Mars in 2020.

12 Aug 2004

WHO tackles the parasitic disease Leishmaniasis in Afghanistan

A rapid intervention by the World Health Organization and its partners, the Massoud Foundation and HealthNet International, in Kabul, Afghanistan, made possible by a donation from the Belgian government, should dramatically reduce the incidence of leishmaniasis in less than two years.

10 Aug 2004

Binge drinking accounts for a substantial number of deaths each year in the United States

Binge drinking and harmful drinking, including both medium to high levels of regular alcohol consumption, account for a substantial number of deaths each year in the United States.

9 Aug 2004

Liver transplantation outcomes have significantly improved for patients with hepatitis B

Since the early 1990s, therapeutic options for patients undergoing liver transplantation for hepatitis B have evolved to include HBV immune globulin (HBIG) and lamivudine.

9 Aug 2004

Significant advance in the understanding of the hepatitis C virus (HCV)

Researchers have made a significant advance in the understanding of the hepatitis C virus (HCV) by identifying new genetic factors associated with clearing the virus spontaneously without the necessity for additional treatment.

9 Aug 2004

Correlation between HCV viral load and severity of liver disease

The significance of hepatitis C virus (HCV) serum titers (HCV viral load) has been examined in several clinical situations. There is much evidence that patients with a lower viral load have better response rates to anti-viral therapy compared to those with higher levels.

9 Aug 2004

Self-recovery from Hep C infection linked to genes that suppress action of killer immune cells

In a study to be published in Science online Aug. 6, researchers at Johns Hopkins have found that genes involved in suppressing the body's defensive "killer" immune cells are a potential key factor in spontaneous recovery from hepatitis C.

5 Aug 2004

PET is a more accurate way to diagnose recurrent melanoma than the present, standard procedures

A new study using positron emission tomography (PET) determined PET is a more accurate way to diagnose recurrent melanoma than the present, standard procedures.

5 Aug 2004

Mefloquine, an anti-malarial drug plays a critical role in movement, vision and memory

Brown University researchers have discovered that mefloquine, an anti-malarial drug, blocks two gap junction proteins, or connexins, in low doses and with very few side effects in the brains of laboratory mice.

5 Aug 2004

Metabasis Therapeutics announces multi-center Phase 2 study to evaluate the orally administered antiviral compound remofovir mesylate

Metabasis Therapeutics has announced the initiation of a multi-center, multi- national Phase 2 study to evaluate the orally administered antiviral compound remofovir mesylate in chronic hepatitis B (HBV) infected patients.

3 Aug 2004

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Early intervention with a novel kind of "smart gene therapy" might effectively prevent the organ damage commonly suffered by heart attack victims, suggests a new animal study by researchers at Brigham and Women's Hospital in Boston and Duke University Medical Center.

2 Aug 2004

Researchers have secured more than $19.4 million for their work on cardiovascular and liver diseases and HIV/AIDS

Sydney University medical researchers have secured more than $19.4 million for their work on cardiovascular and liver diseases and HIV/AIDS in the latest round of National Health and Medical Research Council program grants.

2 Aug 2004

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

By altering the expression of a single -- albeit different – gene, Drs. Roger Davis (UMASS Medical School, USA) and Ying-Hue Lee (Academia Sinica, Taiwan) have succeeded in creating two different strains of transgenic mice that don't gain weight, even when fed fat-laden, high calorie diets.

2 Aug 2004

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Eli Lilly and Company have announced that the Oncologic Drugs Advisory Committee (ODAC) of the U.S. Food and Drug Administration positively endorsed Alimta® (pemetrexed), an antifolate, for accelerated approval in the second-line treatment of non-small cell lung cancer.

29 Jul 2004

Study shows safe, effective therapy for previously untreated patients with HIV & hepatitis C

An international study with nearly 900 patients co-infected with Human Immunodeficiency Virus (HIV) and hepatitis C virus (HCV) has shown that HCV can be treated effectively and safely, without compromising the patient’s HIV therapy.

29 Jul 2004

New drug combination more effective than the previous generation of hepatitis C/HIV therapy

A new study reveals the highest efficacy rates ever reported among patients co-infected with hepatitis C and HIV treated with pegylated interferon and ribavirin.

28 Jul 2004

FDA approval for VYTORIN for the treatment of high LDL cholesterol (LDL-C)

Merck/Schering-Plough Pharmaceuticals has announced that the U.S. Food and Drug Administration has approved VYTORIN™ (ezetimibe/simvastatin) for the treatment of high LDL cholesterol (LDL-C) in patients with primary hypercholesterolemia or mixed hyperlipidemia as adjunctive therapy to diet when diet alone is not enough.

26 Jul 2004

Liver News and Research

Paracentesis performed in an outpatient setting by gastrointestinal endoscopy assistants is safe

Organ transplant recipients infected with West Nile virus develop more severe neurological illness

New imaging technique may help cystic fibrosis sufferers

British team and NASA plan to take stem cells into space

WHO tackles the parasitic disease Leishmaniasis in Afghanistan

Binge drinking accounts for a substantial number of deaths each year in the United States

Liver transplantation outcomes have significantly improved for patients with hepatitis B

Significant advance in the understanding of the hepatitis C virus (HCV)

Correlation between HCV viral load and severity of liver disease

Self-recovery from Hep C infection linked to genes that suppress action of killer immune cells

PET is a more accurate way to diagnose recurrent melanoma than the present, standard procedures

Mefloquine, an anti-malarial drug plays a critical role in movement, vision and memory

Metabasis Therapeutics announces multi-center Phase 2 study to evaluate the orally administered antiviral compound remofovir mesylate

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Researchers have secured more than $19.4 million for their work on cardiovascular and liver diseases and HIV/AIDS

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Study shows safe, effective therapy for previously untreated patients with HIV & hepatitis C

New drug combination more effective than the previous generation of hepatitis C/HIV therapy

FDA approval for VYTORIN for the treatment of high LDL cholesterol (LDL-C)

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